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Aclovir (Acyclovir)
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Aclovir

Aciclovir (ACV) is an antiviral medication. It is primarily used for the treatment of herpes simplex virus infections, chickenpox, and shingles. Other uses include prevention of cytomegalovirus infections following transplant and severe complications of Epstein-Barr virus infection.

Other names for this medication:
Accrivir, Aciherpin, Acirax, Acivir, Acvirax, Acycloguanosine, Acyclor, Acyclovir, Acylab, Alovir, Axovir, Cevirin, Civir, Clovir, Clovirax, Clyvir, Cutivir, Cycloex, Cyclopiz, Herpex, Herporax, Herpovir, Kayvir, Lovir, Nisivir, Ocuvir, Okavir, Ophtrhovir, Oveer, Psyvir, Ridoherp, Rivol, Rovir, Rowapil, Setuvir, Spaclovir, Trikase, Virclo, Viroxit, Virucid, Vivorax, Zovir, Zoylex

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Also known as: Acyclovir

Description

{name} (acyclovir) is an antiviral drug. Acyclovir slows the growth and spread of the herpes virus in the body.

{name} is used to treat infections caused by herpes viruses, such as genital herpes, cold sores, shingles, and chickenpox.

{name} will not cure herpes, but it can lessen the symptoms of the infection.

Dosage

Patient information about the treatment of herpes, chickenpox, or shingles is available with this medicine. Read it carefully before using this medicine.

Acyclovir is best used as soon as possible after the symptoms of herpes infection or shingles (for example, pain, burning, blisters) begin to appear.

If you are taking acyclovir for the treatment of chickenpox, it is best to start taking acyclovir as soon as possible after the first sign of the chickenpox rash, usually within one day.

Acyclovir capsules, tablets, and oral suspension may be taken with meals or on an empty stomach.

Acyclovir is best taken with a full glass (8 ounces) of water.

If you are using acyclovir oral suspension, use a specially marked measuring spoon or other device to measure each dose accurately. The average household teaspoon may not hold the right amount of liquid.

To help clear up your herpes infection, chickenpox, or shingles, keep taking acyclovir for the full time of treatment, even if your symptoms begin to clear up after a few days. Do not miss any doses. However, do not use this medicine more often or for a longer time than your doctor ordered.

If you are taking acyclovir capsules, tablets, or oral suspension, you should drink plenty of water to avoid becoming dehydrated.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules, oral suspension, or tablets): For treatment of genital herpes: Adults and children 12 years of age and older—200 milligrams (mg) five times a day for ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For prevention of recurrent outbreaks of genital herpes infections: Adults and children 12 years of age and older—200 to 400 mg two to five times a day for five days or up to twelve months, depending on how often your outbreaks of infection occur. Children up to 12 years of age—Use and dose must be determined by the doctor. For treatment of chickenpox: Adults and children who weigh over 88 pounds (40 kilograms)—800 mg four times a day for five days. Children 2 years of age and older and weighing 88 pounds (40 kilograms) or less—Dose is based on body weight and must be determined by the doctor. The usual dose is 20 mg per kilogram (kg) of body weight, up to 800 mg, four times a day for five days. Children up to 2 years of age—Use and dose must be determined by the doctor. For treatment of shingles: Adults and children 12 years of age and older—800 mg five times a day for seven to ten days. Children up to 12 years of age—Use and dose must be determined by the doctor. For injection dosage form: For treatment of herpes of the brain, genitals, or mucous membranes, or for the treatment of shingles: Adults and children 12 years of age and older—Dose is based on body weight and must be determined by the doctor. The usual dose is 5 to 10 mg of acyclovir per kg (2.3 to 4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period, and repeated every eight hours for five to ten days. Children up to 12 years of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg to 20 mg of acyclovir per kg (4.5 mg to 9.1 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for seven to ten days. For treatment of widespread herpes virus infection in newborns: Infants from birth to 3 months of age—Dose is based on body weight and must be determined by the doctor. The usual dose is 10 mg of acyclovir per kg (4.5 mg per pound) of body weight, injected slowly into a vein over at least a one-hour period and repeated every eight hours for ten days.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Aclovir dosage information

Side effects

The most common side effects associated with Aclovir are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid getting this medication in your eyes, nose, or mouth. If this does happen, rinse with water. When treating a cold sore, apply the medication only to the outer part of your lips.

Avoid using other medications on the areas you treat with Aclovir Topical unless your doctor tells you to.

Using Aclovir Topical will not prevent you from passing genital herpes to other people. Herpes infections are contagious and you can infect other people even while you are using acyclovir.

Avoid sexual intercourse or use a latex condom to help keep you from spreading the virus to others. Avoid letting infected areas come into contact with other people. Avoid touching an infected area and then touching your eyes. Wash your hands frequently to prevent the spread of infection.

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Comparison of induced sputum with bronchial wash, bronchoalveolar lavage and bronchial biopsies in COPD. Pathological processes affecting the ICA, in association with an ipsilateral fetal posterior cerebral artery (PCA), resulting in parieto-occipital strokes are rarely reported. Localization of Simian immunodeficiency virus-infected cells in the genital tract of male and female Rhesus macaques. Cellular 5-LOX activation was obtained by adding calcium ionophore (A23187) into the pouch thus providing a novel model to evaluate the efficacy and selectivity of 5-LOX inhibitors. Postmortem examination did not reveal macroscopic changes of major organs. The clinical data of 40 adult patients who had undergone operations for isthmic spondylolithesis from June 1977 through June 1994 were reviewed.

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Northern hybridization using the PCR products as probes confirmed that one transcript was tab moduretic dosage actually induced by HWC treatment. However, for hyperalphalipoproteinemia patients the levels of large HDL and serum dolichol were increased, and serum dolichol was mainly associated with the large HDL fraction. There is a robust empirical evidence base supporting the acute efficacy of electroconvulsive therapy (ECT) for severe and treatment resistant depression. In addition, the strategy can be used to prepare other HSP ceramic scaffolds, indicating a universal application for tissue engineering, mechanical engineering, catalysis, and environmental materials. Since the transcription factor GATA-3 is essential for TH2 cell development and the production of several TH2 type cytokines this intracellular molecule represents a new promising target for therapeutic intervention in asthma that might even effect airway remodelling. A randomized controlled trial was conducted with the objectives of to find out the incidence of feed intolerance in vigorous neonates with MSAF who received gastric lavage (GL) as compared to those in whom it was not performed.

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