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Aldezole (Metronidazole)
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Aldezole

Aldezole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

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Also known as: Metronidazole

Description

Aldezole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Aldezole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.

Dosage

Aldezole 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Aldezole and 250 on the other side; bottles of 50, 100, and 2,500. Aldezole 500-mg tablets are oblong, blue, film coated, with Aldezole debossed on one side and 500 on the other side; bottles of 50, 100, and 500.

Overdose

In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Aldezole overdose, Aldezole infusion should be discontinued. Patients should be treated symptomatically.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Aldezole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metronidazole injection in the elderly. However, elderly patients are more likely to have unwanted effects and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving metronidazole injection.

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Ang II increased IL-6 mRNA expression via NF-kappaB and CREB in an extracellular signal-regulated kinase (ERK)-dependent manner in rat VSMCs. Our analyses promote the understanding of the genome polymorphism of the Beijing family strains and provide the molecular genetic basis for their wide dissemination capacity and drug resistance. Although improvements in image quality were measured and the artifact was less pronounced, the artifact was still present. Wiki-based clinical practice guidelines for the management of adult onset sarcoma: a new paradigm in sarcoma evidence. Potent antinociceptive effects of kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats. Early auditory evoked potentials (EAEPs) were measured in rabbits. Giant enhancement of the optical second-harmonic emission of WSe(2) monolayers by laser excitation at exciton resonances. Calibration curve corresponding to analyte concentration ranging from 0.3 to 25 microg mL(-1) was obtained with a limit of detection 0.1 microg mL(-1). Furthermore, CHD patients with two different patterns in Traditional Chinese Medicine clinical practices could be classified by the corresponding metabolic profiles, and several potential biomarkers were discussed. She had severe hyperemesis, palpitation at 6 weeks of gestation and many episodes of paroxysmal VT, but no apparent organic heart disease.

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To develop a new therapeutic monoclonal Antibody (mAb) for Hodgkin lymphoma (HL), we immunized a BALB/c mouse with live HL cell lines, alternating between two HL cell lines. Outcomes were assessed by questionnaire evaluation, physical examination, and radiographs. A computational model of the eye was developed such that 21 factors could be varied independently or simultaneously. Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells. ON axon number was significantly increased in the un-injected eye but decreased in the KA-injected eye. Finding features for real-time premature ventricular contraction detection using a fuzzy neural network system.

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Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis. Whether susceptibility for other cardiomyopathies, such as dilated cardiomyopathy, can be conferred by mutations in JPH2 warrants investigation. Cell proliferation was quantified by incorporation of 3H-thymidine. The concept of endocrine disruption emerged over a decade ago with the observation that several natural or industrial compounds can interfere with estrogen and androgen signaling, and thereby affect both male and female reproductive functions. Patients may present with clear indications for surgery, but most require balancing benefits against intraoperative and late complications. Dexlansoprazole MR is highly effective in healing EO and offers benefits over lansoprazole, particularly in moderate-to-severe disease. Remaining root dentin thickness in mesiobuccal canals of maxillary first molars after attempted removal of broken instrument fragments. A second threshold for the mobility exists which has a lower value as the ratio between diffusion coefficients decreases. The concordant alternans which was transformed from a discordant one by a VPB was not remarkably potentiated by a VPB, or by prolongation or shortening of the cycle length.

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A total of 1361 patients underwent thyroid surgery between May 1994 and December 2007 at a single institution. Chronically nitrate-loaded riparian buffer zones show high N(2)O emissions. The authors give an account of twelve cases of inflammatory acute abdominal attacks which complicated the course after abdominal operations. A 45-year-old female with oophoritis (pelvic inflammatory disease) caused by Campylobacter fetus (C. The aim of this study was to evaluate the incidence and the characteristics of the infections of ascitic fluid in cirrhotic patients at the moment of hospital admission. Perivascular and parenchymal inducible nitric oxide synthase expression increased up to 24 h in the striatum, whereas in the corpus callosum inducible nitric oxide synthase expression was maximal after 16 h. Stem cell therapy for heart failure: Ensuring regenerative proficiency. This underscores the importance of aggressive diagnostic evaluation of posttransplant cholestasis.

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Alphafetoprotein, cholinesterases and rapidly adhering cells in the prenatal diagnosis of neural tube defects. In vitro and in vivo evaluation of a bondable compact for the prolonged delivery of triamcinolone acetonide to the oral cavity in patients with lichen planus. The final diagnosis was always made by a critical events committee (CEC) using standard criteria. A central role for adenosine in the hypotension elicited by hypoxia in anesthetized rats. It has been reported about poor prognosis in patients with advanced hepatocellular carcinoma (HCC) refractory to hepatic arterial infusion chemotherapy (HAIC). Generally, 5- azaC has its greatest effect on the inactive chromosome regions that are typically late-replicating prior to 5- azaC treatment.

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The aim of this study was to analyze the long-term results of the surgical management of craniopharyngioma in children by reviewing a series of patients consecutively treated in a single institution, and to assess the efficacy of intratumoral chemotherapy with interferon-alpha. Finally, R79x expression correlated with loss of expression of HSP90, a protein relevant to cardiomyocyte apoptosis. Hypoglobulinemia in resting, conditioned sled dogs may reflect the immunosuppressive or catabolic effects of intense endurance training. Characterisation of drug resistance of nosocomial ESBL-producing E. Enhanced M6a-Ib expression in the medial prefrontal cortex (in areas prelimbic and infralimbic cortex) might be interpreted as a compensatory mechanism in response to changes in axonal projections from the hippocampus. DNA binding specificities of transcription factors (TFs) are a key component of gene regulatory processes. Most normal cells stimulated to grow by v-H-ras also cloned poorly in agar, and only rare cells were tumorigenic. A simple and reliable DNA extraction method for dry seeds of Brassica napus has been developed in our laboratory. The method is illustrated in seven patients undergoing upper thoracic spinal reconstruction to define a surgical approach without sternotomy or thoracotomy.

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Logistic regression performed the best for AKI detection (AUC 0.743) and was a close second to the ensemble for AKI prediction (AUC ensemble: 0.664, AUC logistic regression: 0.660). Carbon dioxide contrast enhancement for C-arm CT utility for treatment planning during hepatic embolization procedures. During its infusion, HDM bound heavily within the glomerular basement membrane, and binding of the cationic probes was virtually abolished. Our study is the first to examine gene pairs involved in all recurrent chromosomal translocations observed in tumor cells, and to correlate the location of more than half of breakpoints to positions of known fragile sites. Avoidable waste of research related to inadequate methods in clinical trials. Pseudocyst formation is a well-recognized complication of pancreatitis. The pattern of RNFL thinning seems to be a useful biomarker to identify vigabatrin toxicity. We investigated whether FDP-Sr could be promising in treating diabetic testopathy. Substantia nigra cells, however, give rise to more highly collateralized axons and single cells may simultaneously innervate different regions of cortex as well as subcortical sites.

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To verify whether abdominal pressure during urination represents an important factor in the postoperative development of inguinal hernia after radical retropubic prostatectomy. A comparative study between indobufen and acetylsalicylic acid on beta-thromboglobulin, platelet factor 4 and platelet aggregation in patients with transient ischemic attacks. Recent investigations indicate a potential role of adipocitokines originating from visceral adipose tissue: adiponectin, leptin, resistin and dipepetidyl peptidase-4 (DPP-4) activity in the development of microvascular complications in diabetes. Previous studies have shown that TP508 can accelerate musculoskeletal tissue repair including fracture healing. A systematic review of the PubMed database was performed using the search terms Optos, optomap, panoramic, ultra-widefield, wide-angle, and ellipsoid mirror. Modeling embryo development of Sitona discoideus Gyllenhal (Coleoptera: Curculionidae) under constant temperature. The differentiation-inducing effects of ATRA were not dependent on class I PI3K/mTOR. Moreover, studies in the skin microvasculature suggest that this microvascular dysfunction contributes significantly to the pathogenesis of diabetic foot.

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The present study shows that several European or northeast Atlantic hydroid species, Sertularella conica Allman, 1877, Sertularella rugosa (Linnaeus, 1758), Sertularella tenella Alder, 1856, Sertularella polyzonias (Linnaeus, 1758), and Sertularella fusiformis (Hincks, 1861) have been incorrectly reported from the west coast of North America and suggests that assumptions of cosmopolitanism of some species require verification by continuing refinement of regional species-level taxonomy. Persistent pulmonary hypertension of the newborn: therapeutical approach. This paper will review these risk factors as many are modifiable and care should be taken to address such factors in order to decrease the chance of infection. A clinical model to identify patients with high-risk coronary artery disease. Little is known about the mechanisms dilantin drug class of topiramate-induced weight loss and decreased appetite in children with epilepsy in China and abroad.

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