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Aldezole (Metronidazole)

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Aldezole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Other names for this medication:
Amebidal, Aminidazole, Amodis, Amotein, Anabact, Anaerobex, Anerobia, Arilin, Asuzol, Deprocid, Dumozol, Entizol, Etronil, Filmet, Flagystatine, Flazol, Geloderm, Gnostol, Gynomix, Gynotran, Litagyl, Menizol, Metazole, Metral, Metrobac, Metrolotion, Metronex, Metronid, Metrosept, Metrosil, Metrovax, Metrozin, Missilor, Negazole, Nidazole, Nidazyl, Nipazol, Otrozol, Repligen, Rodogyl, Rosasol, Rovamet, Torgyl, Trichostatic, Tricofin, Unigyl

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Also known as: Metronidazole


Aldezole (generic name: Metronidazole) is an antibiotic that belongs to a group of medicines called nitroimidazoles.

Aldezole is used for the treatment of susceptible anaerobic bacterial and protozoal infections in the following conditions: amebiasis, symptomatic and asymptomatic trichomoniasis; skin and skin structure infections; CNS infections; intra-abdominal infections (as part of combination regimen); systemic anaerobic infections; treatment of antibiotic-associated pseudomembranous colitis (AAPC); bacterial vaginosis; as part of a multidrug regimen for H. pylori eradication to reduce the risk of duodenal ulcer recurrence.


Aldezole 250-mg tablets are round, blue, film coated, with SEARLE and 1831 debossed on one side and Aldezole and 250 on the other side; bottles of 50, 100, and 2,500. Aldezole 500-mg tablets are oblong, blue, film coated, with Aldezole debossed on one side and 500 on the other side; bottles of 50, 100, and 500.


In cases of overdose in adults, the clinical symptoms are usually limited to nausea, vomiting, ataxia and slight disorientation. In a preterm newborn, no clinical or biological sign of toxicity developed.

There is no specific treatment for Aldezole overdose, Aldezole infusion should be discontinued. Patients should be treated symptomatically.


Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Aldezole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of metronidazole injection in the elderly. However, elderly patients are more likely to have unwanted effects and age-related liver, kidney, or heart problems, which may require caution and an adjustment in the dose for patients receiving metronidazole injection.

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Ang II increased IL-6 mRNA expression via NF-kappaB and CREB in an extracellular signal-regulated kinase (ERK)-dependent manner in rat VSMCs. Our analyses promote the understanding of the genome polymorphism of the Beijing family strains and provide the molecular genetic basis for their wide dissemination capacity and drug resistance. Although improvements in image quality were measured and the artifact was less pronounced, the artifact was still present. Wiki-based clinical practice guidelines for the management of adult onset sarcoma: a new paradigm in sarcoma evidence. Potent antinociceptive effects of kelatorphan (a highly efficient inhibitor of multiple enkephalin-degrading enzymes) systemically administered in normal and arthritic rats. Early auditory evoked potentials (EAEPs) were measured in rabbits. Giant enhancement of the optical second-harmonic emission of WSe(2) monolayers by laser excitation at exciton resonances. Calibration curve corresponding to analyte concentration ranging from 0.3 to 25 microg mL(-1) was obtained with a limit of detection 0.1 microg mL(-1). Furthermore, CHD patients with two different patterns in Traditional Chinese Medicine clinical practices could be classified by the corresponding metabolic profiles, and several potential biomarkers were discussed. She had severe hyperemesis, palpitation at 6 weeks of gestation and many episodes of paroxysmal VT, but no apparent organic heart disease.

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To develop a new therapeutic monoclonal Antibody (mAb) for Hodgkin lymphoma (HL), we immunized a BALB/c mouse with live HL cell lines, alternating between two HL cell lines. Outcomes were assessed by questionnaire evaluation, physical examination, and radiographs. A computational model of the eye was developed such that 21 factors could be varied independently or simultaneously. Undifferentiated carcinoma of the colon containing exocrine, neuroendocrine and squamous cells. ON axon number was significantly increased in the un-injected eye but decreased in the KA-injected eye. Finding features for real-time premature ventricular contraction detection using a fuzzy neural network system.

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Gorlin effective orifice areas greater than 0.3 cm(2) have not viscosity effect. ADAM8 (a disintegrin and metalloproteinase 8) protein promotes the invasive and metastatic phenotype of triple-negative breast cancer (TNBC) cells. Unified origin for the 3D magnetism and superconductivity in NaxCoO2. Advances in the pharmacologic management of early Parkinson disease. Use of the PFA-100 apparatus to assess platelet function in patients undergoing PTCA during and after infusion of c7E3 Fab in the presence of other antiplatelet agents. The orientation of the scan planes and the scan parameters including thickness, number of slices and mAs were varied according to the assumed diagnostic problems. In conclusion, the present study provides evidence for the existence of volume flow dependent preferential pathways for leukocyte passage across the capillary network in the rat cremaster muscle. Moreover, despite uptake increasing over exposure time, the cell characteristics exhibit changes predominately after the first 24 hours, highlighting that the cell responses to nanoparticle exposure are not cumulative. Estimates of diagnosed PLWH in New York City and other 19 jurisdictions based on HIV case reporting were compared with those based on HIV laboratory reporting.

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Loss of PLZF expression in prostate cancer by immunohistochemistry correlates with tumor aggressiveness and metastasis. Whether susceptibility for other cardiomyopathies, such as dilated cardiomyopathy, can be conferred by mutations in JPH2 warrants investigation. Cell proliferation was quantified by incorporation of 3H-thymidine. The concept of endocrine disruption emerged over a decade ago with the observation that several natural or industrial compounds can interfere with estrogen and androgen signaling, and thereby affect both male and female reproductive functions. Patients may present with clear indications for surgery, but most require balancing benefits against intraoperative and late complications. Dexlansoprazole MR is highly effective in healing EO and offers benefits over lansoprazole, particularly in moderate-to-severe disease. Remaining root dentin thickness in mesiobuccal canals of maxillary first molars after attempted removal of broken instrument fragments. A second threshold for the mobility exists which has a lower value as the ratio between diffusion coefficients decreases. The concordant alternans which was transformed from a discordant one by a VPB was not remarkably potentiated by a VPB, or by prolongation or shortening of the cycle length.

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ER expression in the gingiva is probably not related to the presence or absence of estrogen supplementation. Most likely this will come from larger studies involving prospective randomization to treatment based on genotype. Immunohistochemical studies localized the renin-immunoreactive substance to cells in the inner region of the cortex. Resistance of the targets could be at least partly attributed to the incapacity of effector cells to bind to them. Steps that can be taken to confirm the validity for a particular application, setting, or population are described. Elution of group-specific substance A from RBC of various subgroups of A and its effect on the agglutination of AX RBC. gammaGTase I and II were released from a wall and membrane fraction of a tomato fruit extract with 1.0 M NaCl, suggesting that they are peripheral membrane proteins. These results suggest that opioid and alpha adrenergic agonists act on separate receptors to produce a synergistic inhibition of the transmission of nociceptive information at the spinal level.

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ACT partner drugs and nonartemisinin regimens with longer prophylactic times could result in a larger impact in higher-transmission settings, although their long term benefit must be evaluated in relation to the risk of development of parasite resistance. Oral and oropharyngeal squamous cell carcinoma (OOSCC) has been linked to high-risk HPV strains. We can detect the SLN and lymphatic flow near to tumors without shine-through effect, especially in the head and neck regions. To investigate the clinical significance of serum Tu M2-PK and CA19-9 detection in the diagnosis of cholangiocarcinoma. Biodistribution and pharmacokinetics of transgenic pig-produced recombinant human factor IX (rhFIX) in rats.

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The spore-bearing alkaliphilic Bacillus species constitute a large, heterogeneous group of microorganisms, important for their ability to produce enzymes, antibodies and metabolites of potential medical use. hawaiiensis is very rarely reported in Europe, it is one of the major rhinosinusitis agents in areas with a relatively warmer climate, such as India or Southwestern USA. Altered lung function might have an influence on PtcO2, and thus affect the oxygen challenge test. Inclusion for analysis was a clinical history of shoulder trauma and electrophysiological evidence of nerve injury. Rhodiola imbricata is a medicinal plant, native to mountainous regions of Asia, parts of Europe, and the Arctic. The findings of 27 cases described in the literature are discussed with special reference to the histological findings of the intestinal wall. Lingual orthodontic treatment and absolute anchorage to correct an impacted maxillary canine in an adult. On-line solid phase extraction coupled to capillary LC-ESI-MS for determination of fluoxetine in human blood plasma. Results indicate that oxybutynin XL is the dominant therapeutic option under a wide range of alternative inputs and assumptions.

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A total of 1361 patients underwent thyroid surgery between May 1994 and December 2007 at a single institution. Chronically nitrate-loaded riparian buffer zones show high N(2)O emissions. The authors give an account of twelve cases of inflammatory acute abdominal attacks which complicated the course after abdominal operations. A 45-year-old female with oophoritis (pelvic inflammatory disease) caused by Campylobacter fetus (C. The aim of this study was to evaluate the incidence and the characteristics of the infections of ascitic fluid in cirrhotic patients at the moment of hospital admission. Perivascular and parenchymal inducible nitric oxide synthase expression increased up to 24 h in the striatum, whereas in the corpus callosum inducible nitric oxide synthase expression was maximal after 16 h. Stem cell therapy for heart failure: Ensuring regenerative proficiency. This underscores the importance of aggressive diagnostic evaluation of posttransplant cholestasis.

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Alphafetoprotein, cholinesterases and rapidly adhering cells in the prenatal diagnosis of neural tube defects. In vitro and in vivo evaluation of a bondable compact for the prolonged delivery of triamcinolone acetonide to the oral cavity in patients with lichen planus. The final diagnosis was always made by a critical events committee (CEC) using standard criteria. A central role for adenosine in the hypotension elicited by hypoxia in anesthetized rats. It has been reported about poor prognosis in patients with advanced hepatocellular carcinoma (HCC) refractory to hepatic arterial infusion chemotherapy (HAIC). Generally, 5- azaC has its greatest effect on the inactive chromosome regions that are typically late-replicating prior to 5- azaC treatment.

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The aim of this study was to analyze the long-term results of the surgical management of craniopharyngioma in children by reviewing a series of patients consecutively treated in a single institution, and to assess the efficacy of intratumoral chemotherapy with interferon-alpha. Finally, R79x expression correlated with loss of expression of HSP90, a protein relevant to cardiomyocyte apoptosis. Hypoglobulinemia in resting, conditioned sled dogs may reflect the immunosuppressive or catabolic effects of intense endurance training. Characterisation of drug resistance of nosocomial ESBL-producing E. Enhanced M6a-Ib expression in the medial prefrontal cortex (in areas prelimbic and infralimbic cortex) might be interpreted as a compensatory mechanism in response to changes in axonal projections from the hippocampus. DNA binding specificities of transcription factors (TFs) are a key component of gene regulatory processes. Most normal cells stimulated to grow by v-H-ras also cloned poorly in agar, and only rare cells were tumorigenic. A simple and reliable DNA extraction method for dry seeds of Brassica napus has been developed in our laboratory. The method is illustrated in seven patients undergoing upper thoracic spinal reconstruction to define a surgical approach without sternotomy or thoracotomy.

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Logistic regression performed the best for AKI detection (AUC 0.743) and was a close second to the ensemble for AKI prediction (AUC ensemble: 0.664, AUC logistic regression: 0.660). Carbon dioxide contrast enhancement for C-arm CT utility for treatment planning during hepatic embolization procedures. During its infusion, HDM bound heavily within the glomerular basement membrane, and binding of the cationic probes was virtually abolished. Our study is the first to examine gene pairs involved in all recurrent chromosomal translocations observed in tumor cells, and to correlate the location of more than half of breakpoints to positions of known fragile sites. Avoidable waste of research related to inadequate methods in clinical trials. Pseudocyst formation is a well-recognized complication of pancreatitis. The pattern of RNFL thinning seems to be a useful biomarker to identify vigabatrin toxicity. We investigated whether FDP-Sr could be promising in treating diabetic testopathy. Substantia nigra cells, however, give rise to more highly collateralized axons and single cells may simultaneously innervate different regions of cortex as well as subcortical sites.

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To verify whether abdominal pressure during urination represents an important factor in the postoperative development of inguinal hernia after radical retropubic prostatectomy. A comparative study between indobufen and acetylsalicylic acid on beta-thromboglobulin, platelet factor 4 and platelet aggregation in patients with transient ischemic attacks. Recent investigations indicate a potential role of adipocitokines originating from visceral adipose tissue: adiponectin, leptin, resistin and dipepetidyl peptidase-4 (DPP-4) activity in the development of microvascular complications in diabetes. Previous studies have shown that TP508 can accelerate musculoskeletal tissue repair including fracture healing. A systematic review of the PubMed database was performed using the search terms Optos, optomap, panoramic, ultra-widefield, wide-angle, and ellipsoid mirror. Modeling embryo development of Sitona discoideus Gyllenhal (Coleoptera: Curculionidae) under constant temperature. The differentiation-inducing effects of ATRA were not dependent on class I PI3K/mTOR. Moreover, studies in the skin microvasculature suggest that this microvascular dysfunction contributes significantly to the pathogenesis of diabetic foot.

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Decline in serum antibody to the capsule of Haemophilus influenzae type b in the immediate postimmunization period. Optimizing PMTCT service delivery in rural North-Central Nigeria: protocol and design for a cluster randomized study. In contrast to the relative stability of tumorigenicity in such variants cultured in vivo, the tumorigenicity of these variant clones passaged in vivo was variable, depending on the variant clone. Among them, eight glycoproteins showed greater than 2-fold elevations in cancer BAL, including Neutrophil elastase (NE), Integrin alpha-M, Cullin-4B, Napsin A, lysosome-associated membrane protein 2 (LAMP2), Cathepsin D, BPI fold-containing family B member 2, and Neutrophil gelatinase-associated lipocalin. A flexible catheter was introduced transcutaneously or transconjunctivally into the extra- or intraconal space. Tryptic digestion is an important component of most proteomics experiments, and trypsin is available from many sources with a cost that varies by more than 1000-fold.

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Early diagnosis, prompt delivery and intensive supportive treatment are critical for improving the prognosis of AFLP. The neuronal uptake site appears to be functionally (and perhaps anatomically) located outside the synaptic cleft, between intrajunctional alpha 1-postsynaptic receptors and extrajunctional alpha 2-adrenoceptors. The Adverse Outcome Index and the rate of uncomplicated vaginal delivery were used to measure overall birth health. Left pyriform sinus fistula complicated by acute suppurative thyroiditis: report of a case. These observations may reflect a clinical situation likely to occur as trough plasma concentrations of protease inhibitors fall below the IC100 for HIV, highlighting the need for adherence to drug regimens containing these inhibitors. This two-way analysis did not show any correlation that might help to identify a subgroup of patients with APC mutation that may be considered attenuated.

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The currently available evidence is insufficient to reliably assess the potential of radioiodine treatment for differentiated thyroid carcinoma with thyroglobulin positive and radioactive iodine negative metastases. Combining subcellular localization predictions and comparisons with desaturases from other organisms like Arabidopsis, we propose a scheme at the whole cell level, including features that are likely specific to secondary endosymbionts. In this article, we review and compare several of the HF risk prediction tools currently available, highlighting their clinical utilities and potential shortcomings. Relatively little is known about the epidemiology of generalized convulsive status epilepticus (GCSE) in acute ischemic and hemorrhagic stroke. The sugar specificity assay indicated that lectin belongs to Gal/Gal NAc-specific group. units could not be activated antidromically from the dorsal columns at stimulus strengths up to 30 V or thirty times threshold for their antidromic excitation from the dorsolateral funiculus. To keep up with the fast development of this field, it is necessary to summarize the construction, characterization, and application of biomimetic smart nanopores/nanochannels.

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A new concept, involved site radiation therapy (ISRT), is introduced as the standard conformal therapy for the scenario, commonly encountered, wherein optimal imaging is not available. Demonstration of characteristic translocations by molecular studies differentiates CNS-EES from cPNET and help clinicians make informed decisions regarding therapy. Extracellular matrix glycoproteins were preserved after decellularization with SDS, triton X-100 and sonication, whereas proteoglycans were not affected by any of the decellularization protocols. Dihydropyridine BAY-K-8644 activates chromaffin cell calcium channels. Estrogen receptor was positive in all cases tested, as was D240 expression in the lymphatic endothelium lining the spindle cell bundles. Increased peripheral alpha-adrenergic response and decreased beta-2-adrenergic response are related to increased vascular tone and result in atherosclerosis. Long-term effects of peroxisome proliferator-activated receptor ligand bezafibrate on N-terminal pro-B type natriuretic peptide in patients cleocin type of antibiotic with advanced functional capacity impairment. HN001 exhibits a much stronger effect than HN019 in this respect.

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An expandable metal stent has been used to treat bronchial collapse due to polychondritis in one patient and extrinsic bronchial compression secondary to bronchogenic tumour in another. Results suggested the occurrence of nine different phylotypes belonging to Type II methanotrophs in the enriched cultures. Lower linoleic acid content was associated with increased risk for non-fatal events. Evidence for two functionally different fibrinogen receptors on hemopoietic cells: the glycoprotein IIb-IIIa and the mitogenic fibrinogen receptor. The higher concentration of irinotecan caused almost seven-time increase, while the lower one caused a five-time increase of the basal sister chromatid exchange frequency, accompanied with significant lowering of the lymphocyte proliferation index.

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The present study shows that several European or northeast Atlantic hydroid species, Sertularella conica Allman, 1877, Sertularella rugosa (Linnaeus, 1758), Sertularella tenella Alder, 1856, Sertularella polyzonias (Linnaeus, 1758), and Sertularella fusiformis (Hincks, 1861) have been incorrectly reported from the west coast of North America and suggests that assumptions of cosmopolitanism of some species require verification by continuing refinement of regional species-level taxonomy. Persistent pulmonary hypertension of the newborn: therapeutical approach. This paper will review these risk factors as many are modifiable and care should be taken to address such factors in order to decrease the chance of infection. A clinical model to identify patients with high-risk coronary artery disease. Little is known about the mechanisms dilantin drug class of topiramate-induced weight loss and decreased appetite in children with epilepsy in China and abroad.

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Targeted FSW interventions are associated with reductions in syphilis risk and STI treatment is associated with reduced HIV risk. Visual modulation of vestibularly-triggered air-righting in the rat. Delivery for women with a previous cesarean: guidelines for clinical practice from the French College of Gynecologists and Obstetricians (CNGOF). Restriction of the protein intake resulted in a marked reduction of the metabolite excretion. These include the slow diffusion and/or instability of the inducer, the time of loss of competence of animal cells to respond to induction, and the amount of vegetal tissue that releases inducer for a limited time. A circuit supporting concentration-invariant odor perception in Drosophila. By listing all nuclear sizes according to their relative frequencies it provided tricor 145 mg a measure for core size variability as a correlate of nuclear pleomorphism. Visuo-spatial processing in a dynamic and a static working memory paradigm in schizophrenia. Unlike the current approaches to asynchronous BCI systems that make use of windowed versions of the EEG data combined with static classifiers, the methods proposed here are based on discriminative models that allow sequential labeling of data.

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18 patients with advanced osteochondral lesions of the elbow treated by autologous osteochondral autograft cylinders and a minimum follow-up of 36 months were included in the study. Random capillary blood glucose cut points for diabetes and pre-diabetes derived from community-based opportunistic screening in India. Atrial fibrillation (AF) is the most common arrhythmia worldwide and has a complex association with physical fitness. Similarly, on IL-8 promoter activity, IGF-I exerted synergistic effects with IL-1beta, but not with TNFalpha. Infants weighing 1,000 grams or less at birth: developmental outcome for ventilated and nonventilated infants. Upon subcellular distribution the latter form of the enzyme is associated with a cell-surface membrane-enriched fraction.

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