Also known as: Desloratadine
Desloratadine and pseudoephedrine is a combination of two medicines used to treat nasal congestion (stuffy nose), sneezing, and runny nose caused by hay fever.
Desloratadine works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.
The pseudoephedrine causes narrowing of blood vessels. This leads to clearing of nasal congestion, but it may also cause an increase in blood pressure in patients who have high blood pressure.
This medicine is available only with your doctor's prescription.
Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .
Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.
Not taking over-the-counter antihistamines and decongestants while taking desloratadine and pseudoephedrine combination.
When taking desloratadine and pseudoephedrine extended-release tablet:
Swallow it whole. Do not crush, break, or chew before swallowing.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
For oral dosage form (extended-release tablets [12 hour]): For nasal congestion or rhinorrhea Adults and teenagers—Oral, one tablet (2.5 milligrams desloratadine, 120 milligrams pseudoephedrine) two times a day 12 hours apart, taken with or without a meal Children 4 years of age and older—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .
For oral dosage form (extended-release tablets [24 hour]): For nasal congestion or rhinorrhea Adults and teenagers—Oral, one tablet (5 milligrams desloratadine, 240 milligrams pseudoephedrine) daily, taken with or without a meal Children 4 years of age and older—Use and dose must be determined by your doctor. Children and infants up to 4 years of age—Use is not recommended .
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose may cause anxiety, trouble sleeping, headache, vomiting, thirst, muscle weakness, fast or pounding heartbeats, hallucinations, shallow breathing, or a seizure.
Keep out of the reach of children.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Do not keep outdated medicine or medicine no longer needed.
Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.