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Alpranex (Alprazolam)

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Alpranex is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alpranex is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alpranex may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Aleez, Alpanol, Alprasert, Alprine, Alprocalm, Alpronit, Alprop, Alprowon, Altin, Altrex, Alzex, Alzoft, Alzopax, Alzot, Ambutech, Anxico, Anxorel, Anzilum, Betapax, Censir, Depser, Endolam, Enxolam, Erazol, Exiten, Fludep, Fluwel, Fluxin, Fultop, Golprax, Himzolam, Hipose, Kaprolam, Luzarn, Mebaspa, Meloprax, Morecalm, Orten, Pralam, Sertamax, Somnirest, Trapose, Trika, Xylonite, Zocam, Zolar, Zolipax, Zolran, Zopax, Zopic

Similar Products:
Colcrys, Nexium, Wellbutrin, Antivert, Celexa, Bactrim, Ilosone, Terramycin

Also known as: Alprazolam


{name} (alprazolam) is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). It is thought that alprazolam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is used to treat anxiety disorders and anxiety caused by depression.

{name} is also used to treat panic disorders with or without a fear of places and situations that might cause panic, helplessness, or embarrassment (agoraphobia).

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alpranex XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Alpranex XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpranex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Since the knowledge about MRI of the inferior alveolar nerve (IAN) is limited, this pilot study aims to identify the prospects and limitations of MRI of the IAN, with special consideration of metal artifacts. Supportive drug measures in the rehabilitation of patients with heart diseases. As a measurement we had brainstem auditory evoked potentials (BAEPs), which include deep generators in the brainstem and midbrain. We have also performed and described a simplified method of polyethylene glycol (PEG) precipitation of an insulin bound antibody in the serum. The disparity of nomenclature and heterogeneity of research methods may contribute to general misunderstanding and confusion and impede the ability to generate high-quality evidence regarding the unique stressors experienced by personnel working with animals. Primary independent variables were start time (morning or evening) and method (prostaglandin or oxytocin). Angiographically defined primary angiitis of the CNS: is it really benign?. Regulation of alloimmune Th1 responses by the cyclin-dependent kinase inhibitor p21 following transplantation. Although indiscriminate ligation of the patent ductus arteriosus in all patients is not supported by the available information, the recent suggestion declaring the ductus harmless is not supported either.

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However, because many environmental and adverse social exposures disproportionately affect minorities, understanding the role that epigenetics plays in the human response to these exposures that often result in disease, is critical to reducing disparities in morbidity and mortality. Sensitive detection of Escherichia coli O157:H7 in food and water by immunomagnetic separation and solid-phase laser cytometry. Finally, we measure the thermal fluctuations of the nanocantilevers in water and compare the observed dissipation and frequency shifts with theoretical predictions. Both digital in-line holography (DIH) and zone plate-based microscopy have received considerable interest as powerful imaging tools. Electrical stimulation of the previously axotomized sciatic nerve at A-fiber intensity resulted in many labeled profiles in laminae I-V of the lumbar spinal cord on the experimental as compared to the contralateral side. We observe that RCL2 and KINFix offer comparable histomorphology and superior template for molecular analyses than formalin. Frequently, many of these metabolic manifestations, or what has been termed Syndrome X, antecede the development of overt diabetes by many years. P53 expression in the HuH7 and HepG2 cell lines increased after internal and external irradiation with iodine-131. High-resolution CT scans of the temporal bones and vestibulocollic responses in sternocleidomastoid to both clicks and transmastoid galvanic stimulation (3 mA/2 msec) were studied in four patients with the Tullio phenomenon (one bilateral).

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The aim of this study was to develop a cell-surface display system for foreign antigens on the surface of a Lactococcus lactis strain using an H and W domain of PrtB from Lactobacillus delburueckii subsp. Furthermore, it provides a biologically plausible and statistically robust means of developing continuous reference ranges from early childhood to old age. Bioactivity response of Ta1-xOx coatings deposited by reactive DC magnetron sputtering. In adulthood, the rats were tested on the Whishaw tray reaching task, activity box, novel object recognition, and elevated plus maze. Ultrasonic-assisted enzymatic hydrolysis can be applied to obtain favorable antioxidant hydrolysates from porcine liver with potential applications in food products for preventing lipid oxidation. Study of the entry of isolated metaphasic chromosomes into mammalian cells. The mice further exhibit reduced circulating adiponectin levels that ultimately lead to impaired lipid clearance, and inflamed and fibrotic white adipose tissues. Sex differences in adenosine deaminase activity of stroke patients. Using the transient-time correlation function formalism, we show how NEMD simulations can be extended to study the rheological properties of liquid copper subjected to low, experimentally accessible, shear rates. The reasons leading physicians to choose DS were large thrombus burden on top of resolution of chest pain and normalization of the ECG.

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OLV in pigs results in a substantial V/Q mismatch, hyperperfusion, and alveolar damage in the dependent lung and may thus contribute to gas exchange impairment after thoracic surgery. In particular, phospholipase A2 homologues appear to play an important role. APOE and CETP TaqIB polymorphisms influence metabolic responses to Hibiscus sabdariffa L. Senescent stromal cells induce cancer cell migration via inhibition of RhoA/ROCK/myosin-based cell contractility. Serum levels of valproic acid during delivery in mothers and in umbilical cord - correlation with birth length and weight.

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Molecular therapies are also discussed with particular attention to drug delivery methods and gene therapies. Without conventional antigen-loading, DCs derived from the minigene-modified hPSCs were ready to prime a tumour antigen-specific T cell response and further expand these specific T cells in restimulation processes. The PERG N95:P50 ratio was subnormal in keeping with retinal ganglion cell involvement. In addition, other strategies, which make the design process simpler and more robust, are introduced. Moreover, RhoD(G26V) microinjected into fertilized eggs and embryos of Xenopus laevis caused cleavage arrest only in the injected cells, and the uncleaved cells contained multiple nuclei.

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Assessment of clinical features, radiological and imaging of osteoarthropathy in MPS type II and their evolution under ERT. Participants underwent 4.7 Tesla functional magnetic resonance imaging (fMRI) while performing an emotional Go/NoGo task. If this view is accepted, it has great implications for paediatric practice. We integrated an open-source platform for mobile data collection commonly used in the developing world with an open-source, standard platform for electronic data capture in clinical trials. Separation and identification of antibacterial chamomile components using OPLC, bioautography and GC-MS. He had an eight-year history of chronic diarrhoea, which pre-dated the HIV diagnosis and did not improve after the introduction of combination antiretroviral therapy. The imaging modalities reviewed include ultrasonography, technetium-99m sestamibi imaging, and four-dimensional computed tomography. On the contralateral femur, 6 grafts were stabilized with a calcium triglyceride osteoconductive bone cement. Immunoprecipitation and Western blot analyses show that these chimeric proteins were recognized by HIV-1 positive human sera and antisera raised against V3 peptides, as well as by rabbit anti-gp120 serum. The mean of the solute flux through membrane pores depends on the random distribution and permeability of the pores.

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Self-rating by the patient, rating by the observer, expression and behaviour and somatic indicators are taken into consideration. Genomic DNA was also isolated from each of the 12 tumors and amplified using PCR CLDN1 specific primers. The prophylactic use of intravitreal antivascular endothelial growth factors (anti-VEGF) drugs and steroids in these patients, even if effective, brings some concerns with regard to possible side effects. Pharmacoeconomic Analysis Of Various Treatment Strategies For Patients With Chronic Venous Insufficiency Of The Lower Limbs. Effect sizes were generated as standardized mean differences of cytokine concentrations between patients with PD and healthy controls and converted to the Hedges g statistic. A new model for effective oxygen diffusivity of parenchyma tissue is proposed that not only accounts for the tortuosity of interconnected voids, but also for significant diffusion across cells where the void network is not connected. Intractable skin necrosis sometimes causes lethal sepsis because it progresses rapidly as a result of mechanical stress. Pathological examination of the specimen of rectal carcinoma retains a very strong prognostic value after preoperative radiation therapy. A 30-min soaking period prior to fecal flotation for 15 min allowed fecal pellets to soften and facilitated efficient egg isolation.

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We screened 1,000 healthy people, using a previously developed differential PCR method combined with single-strand conformation polymorphism and amplification-created restriction site methods for the carrier detection of the CYP21 gene deficiency. Severity prediction rules in community acquired pneumonia: a validation study. Neural mechanism of optokinetic nystagmus (input of the superior colliculus). CR1 and CR2 were present in the CR elicited by the brachium pontis CS. Three important advances have expanded greatly the power of the technique, and permitted its implementation on modern synchrotron radiation beamlines. We construct adenovirus vectors containing the lumican gene by gateway recombinant cloning technology, which provides a basis for investigating the role of lumican gene in the pathogenesis of high myopia.

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The calculated phonon dispersions compare better with experiment than earlier results obtained from dynamical mean-field theory. Anti-CD28 ligation alone was capable for co-operating with Grb-2 or Grb-2-Vav1. To assess the levels of quality of life (QoL) in major depressive disorder (MDD) patients treated with either duloxetine or a selective serotonin reuptake inhibitor (SSRI) as monotherapy for up to 6 months in a naturalistic clinical setting mostly in the Middle East, East Asia, and Mexico. There is currently no effective medical treatment to reduce or prevent hypertrophic scarring. We conducted semi-structured interviews with 12 midwives and 12 pregnant women from two regions in NSW in 2008-09 to explore attitudes towards alcohol consumption during pregnancy, and the factors that may encourage or inhibit women from following the recommendation to abstain from drinking while pregnant. In this study, the cellular expression of the NMDAR1 (NR1) and NMDAR2A and B (NR2A and B) subunits was investigated in the human cerebral cortex by immunocytochemistry with antibodies that recognize the NR1 or the NR2A and B subunits of the NMDA receptor. Compound synthesis was confirmed by IR, NMR, UV-vis and emission spectroscopy. One of the most important goals of condensed matter physics is materials by design, i.e. The brackets were debonded with a sharp-edged debonding pliers in a universal testing machine. Parkinsonism may occur after brain lesions such as subarachnoid hemorrhage (1), hydrocephalus (2,3), slit ventricle (4), or shunt revision (5).Until now, pathogenesis remains unclear.

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Even the activated p53delta30 variant, which lacks the self-inhibiting carboxy terminal domain, has a half-life of only 8 min at 37 degrees C in vitro. Research Progress on Notch Signal Pathway in Acute Graft-Versus-Host Disease -Review. In another series, kindling acquisition was compared among three thalamic sites as well as with the amygdala and hippocampus. This article reviews the demographics, presentation, cause, clinical findings, and treatment of 12 cases of cervical necrotizing fasciitis of odontogenic origin. The aim of the present study was to investigate whether CMV infection is related to abdominal aortic aneurysm rupture. Additionally, seven of the NC-genes showed signs of relaxation of purifying selection in the famously species-rich lineage of cichlid fishes. A-MQD was an effective treatment for pain, and this study treatment was associated with improvement of both objective and subjective sleep parameters in participants with chronic osteoarthritic pain. yolk and albumen) and had reduction in the number of positive eggshell surfaces. The results were not affected by the duration of TCs and the parts during the TCs.

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C-statistic ranged from low of 0.709 (sepsis severity score) to high of 0.838 (Angus cohort), suggesting good to excellent model discrimination. Men underwent baseline DW-MRI in addition to standard sequences. As long as evidence for effectiveness is weak, SLIT cannot be firmly recommended in clinical practice. Variations in the normal anatomic osseous contours, including those related to the medial and lateral condyles, were present in all specimens. Umbilical metastasis of mucinous adenocarcinoma of the colon diagnosed by fine needle aspiration cytology. Algorithms for computing the convex basis and elementary modes developed earlier are briefly reviewed.

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Here we show that influenza virus replication in mouse bone marrow-derived DCs is abortive, despite viral genome transcription and replication occurring for each gene segment and viral hemagglutinin and nucleoprotein, at least, being produced. Can Abdominal Wall Reconstruction Be Safely Performed Without Drains?. These regions are deformable and give rise to bidirectionally polarized nuclear spins as spin-resolved electrons flow across their boundaries. Fluorescent red is the best candidate for trap color, while clear and white are the least desirable. When consent is not enough: the construction and development of the modern concept of autonomy. Fungal Endophyte Diversity and Bioactivity in the Indian Medicinal Plant Ocimum sanctum Linn. A personalized treatment strategy formalizes evidence-based treatment selection by mapping patient information to a recommended treatment. This study aimed to assess whether patients with minimal streak or dot exudates within one disc diameter of the fovea can be monitored in a screening programme without compromising visual acuity.

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Objective changes in motor function during placebo treatment in PD. The treatment modality (primary or salvage LDLT) was not observed to affect overall or disease-free survival significantly on multivariate analysis. Haemorrhagic cystitis: incidence and risk factors in a transplant population using hyperhydration. The findings suggest that general practitioners order pathology and imaging tests more often during first presentations of GI symptoms, and often refer patients when GI symptoms are unresolved. Magnetic interactions in compositionally modulated nanowire arrays. Yet, renal mass biopsy is associated with limitations and, as such, may not be appropriate for all patients. The molecular basis for genetic polymorphism of human deoxyribonuclease II (DNase II): a single nucleotide substitution in the promoter region of human DNase II changes the promoter activity. Construction work involves significant physical, mental, and temporal task demands. These agents appear to have a beneficial effect on melasma improvement. These data suggest that proposals to increase district size to increase competition among transplant programs could result in improved organ utilization over time by incentivizing the use of marginal donor organs and increasing access to transplantation.

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To assess the sustained release behavior of doxorubicin from the nanoparticles, we have developed a new simple method based on the permeability coefficient of a synthetic membrane mounted on Franz diffusion cell system. The significant increase in throughput and reduction in cost required us to address some fundamental questions, such as how many transcript tags do we have to sequence for a given transcriptome?. Bidirectional sex change probably evolved from gonochorism in a common ancestor of Trimma and Priolepis. The interaction of the OpaA protein of Neisseria gonorrhoeae MS11mk with heparan sulphate-containing proteoglycan receptors on Chang conjunctiva epithelial cells was examined using isolated receptor binding and cell adherence/internalization assays. Development and application of HPLC-RI and HPLC-MS/MS based methods for quantification of residual deoxycholate levels in pneumococcal polysaccharides. His relapse was localized to the nimotop 30 mg indication pelvis, managed with robotic surgery, and achieved a complete resection with tumour markers normalized.

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The purpose of this study was to determine the usefulness of laparoscopic ultrasound (LUS) during laparoscopic adrenalectomy (LA) and to define the ultrasound imaging characteristics of various adrenal tumors. The most promising derivatization approaches are evaluated, and the strengths and limitations of these approaches are discussed. The expression of iNOS mRNA and protein was examined using reverse-transcription polymerase chain reaction and Western blot analysis. The electrophoretic and chromatographic profiles of the four other variants are normal and do not show any anomalies, and their identification was only possible with sequencing. Electron microscopic observation showed that apoptotic cell death occurred in certain cells in the myometrium bearing adenomyotic changes. In this study, we develop a reliable behavioral marker tool for assessing nontechnical skills that are critical to the success of ward-based multidisciplinary healthcare teams. The aim of this study was to develop an efficient quantitative method for the determination of acetaldehyde (AA) and formaldehyde (FA) contents in solid and liquid food matrices. The standard approach to vascular trauma involves arterial exposure and reconstruction using either a vein or polytetrafluoroethylene graft. Thus, the site-specific fucosylation of the N-linked oligosaccharide on the tailpiece of the alpha1 chain became evident for normal human serum IgA1. Here, we report the synthesis of the derivatives of conjugate 1 and demonstrate that these epigenetically active molecules could be developed to improve the induction of pluripotency factors.

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