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Alprastan (Alprazolam)

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Alprastan is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Alprastan is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Alprastan may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Albiz, Alpkair, Alprax, Alpron, Alprowon, Alsert, Altin, Alzolam, Alzopax, Anxilam, Anxizam, Anxyl, Anzal, Anzilum, Ateez, Azicalm, Betapax, Calmef, Copax, Cozac, Dazolam, Elflu, Elzopam, Endolam, Enxolam, Ezoprax, Fluti, Fluxozam, Procalm, Sertamax, Setex, Silam, Sinozol, Suzilam, Tenschem, Tensyl, Tenzorid, Unixl, Viprax, Zedep

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Usual Adult Dose for Anxiety:

Immediate-release tablets: 0.25 to 0.5 mg orally administered 3 times a day -Maximum dose: 4 mg/day

Usual Adult Dose for Panic Disorder:

Immediate-release tablets: 0.5 mg orally administered 3 times a day -Maximum dose: 10 mg/day Extended-release tablets: -Initial dose: 0.5 to 1 mg orally once a day -Maintenance dose: 3 to 6 mg orally per day, preferably in the morning -Maximum dose: 10 mg/day Comments: -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage. -The daily dosage may be decreased by no more than 0.5 mg every 3 days; however, some patients may require an even slower dosage reduction. -The dose of extended-release tablets may be increased at intervals of 3 to 4 days in increments of no more than 1 mg per day. -The times of administration should be distributed as evenly as possible throughout the waking hours.

Usual Geriatric Dose for Anxiety:

Elderly or debilitated patients: Immediate-release tablets: 0.25 mg orally administered 2 or 3 times a day.

Usual Geriatric Dose for Panic Disorder:

Elderly or debilitated patients: Immediate-release tablets: -Initial dose: 0.25 mg orally administered 2 or 3 times a day Extended-release tablets: -Initial dose: 0.5 mg orally once a day Comments: -If side effects develop, the dose may be lowered. -The lowest possible effective dose should be administered and the need for continued treatment reassessed frequently. -Dosage should be reduced gradually when discontinuing therapy or when decreasing the daily dosage.

Detailed Alprastan dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprastan XR dosage information

Side effects

The most common side effects associated with Alprastan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not drink alcohol while taking Alprastan XR. This medication can increase the effects of alcohol. Alprastan XR can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Grapefruit and grapefruit juice may interact with Alprastan XR and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Severe acute measles pneumonitis: virus isolation in bronchoalveolar lavage fluid. From a pharmacological point of view, the key factor of the efficacy of antibiotic prophylaxis is to attain bactericidal levels of antibiotic in serum and tissues (target site) during the whole intraoperative and early postoperative period. MGAP is applied to assembled nucleotide sequence datasets that are provided via the IMG submission site. Type 2 neurons have small somata and short processes, and can be subdivided on the basis of soma size into dense and light staining categories. Surface electromyograms(EMG) during test contractions (TCs) were studied to assess the muscle strain in simulated mushroom picking. Approach to the Patient with a Suspected Cutaneous Adverse Drug Reaction. Participation in OLTA was associated with better self-rated health and higher life satisfaction regardless of gender or age. Malonylglucoside of all the aglycones, total genistein (TGin), and total daidzein (TDin) showed strong correlation with total isoflavones, whereas acetylglucoside and aglycone levels did not significantly correlate with total isoflavone.

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Recombinant antibodies against tetanus neurotoxin can be useful in tetanus management. Melanosome Motility in Fish Retinal Pigment Epithelial (RPE) Cells. In this work, functional V2O5-C-SnO2 hybrid nanobelts (VCSNs) with a stable structure are introduced where the ultradispersed SnO2 nanocrystals are tightly linked with glucose on the V2O5 surface. Polycystin-1 localized in the basal body of Tg737(orpk/orpk) endothelial cells is insufficient for a fluid shear stress response. Conversations in Cardiology is a new use of modern email communication to facilitate transfer of medical knowledge. Mesenchymal stem cells (MSCs) have been shown to improve tissue regeneration in several preclinical and clinical trials. The specific features of the anatomical structure of the artery of labyrinth (an anatomical and topographical study).

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A microsatellite-based estimation of clonal diversity and population subdivision in Zostera marina, a marine flowering plant. Self-reported and clinician-rated ADHD symptom data from 105 adults in the community already receiving medication treatment who were entering cognitive behavioral therapy studies were examined. The increase of histamine content in both phases were not inhibited by pre-treatment of emedastine difumarate (EME), an anti-allergic drug. Gastrointestinal parasitism of goats in hilly region of Meghalaya, India. Using a specific antibody for UNC-60B, we found varying protein levels of UNC-60B in mutant animals, and that UNC-60B was expressed in embryonic muscles. Aspirin responsiveness in acute brain ischaemia: association with stroke severity and clinical outcome. Settings were modified to compare fixed versus randomly varied stimulus repetition rate, as well as 30 Hz and 100 Hz low pass filters.

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Production of the angiotensin I converting enzyme inhibitory peptides and isolation of four novel peptides from jellyfish (Rhopilema esculentum) protein hydrolysate. Balance of two secretion pathways of nerve growth factor in PC12 cells changes during the progression of their differentiation, with a decrease in constitutive secretion in more differentiated cells. Axial-bonding heterotrimers based on tetrapyrrolic rings: synthesis, characterization, and redox and photophysical properties. Plasma and urine pharmacokinetic samples were collected at defined times. Uptake and distribution of rubidium-86 and potassium-43 in mice and rats--an autoradiographic study. However, when the initial concentration of the inert particles is uniform and high, we show that additional influence of interference between reaction and correlated diffusion accelerates the transient decay of the survival probability in the diffusion-controlled limit. Live embryos pre-incubated with serotonin showed a higher mitochondrial potential, indicating that it can modulate mitochondrial potential. Drug discovery and development process is nowadays conducted in relatively standardised sequence of phases, starting with Discovery and being followed by Preclinical, Clinical and Non-Clinical Development. Inhibition of myocardial inward rectifier potassium current by propylbutyldopamine.

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We examined the impact on glucose and lipid profiles of treating Chinese patients using pegylated interferon (Peg-IFN)-a and ribavirin (RBV). We retrospectively analyzed 50 pathologically confirmed intramuscular masses on MRI. Evaluation of noradrenaline and atrial natriuretic hormone concentration in blood serum of pharmacologically untreated patients with chronic heart failure. Interviews with two samples of German hospital psychiatrists were undertaken to study treatment patterns with respect to antipsychotic nonresponse. We describe the development of imaging assays to investigate these host-pathogen interactions through gene perturbation screens, which could lead to the identification of novel effectors of cordarone 200 mg tabletti the host response to bacterial infection. Hepatocyte growth factor is elevated in chronic lung injury and inhibits surfactant metabolism.

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Low-speed motor vehicle crashes--marginal values for whiplash-associated disorders. Recently, honey bee colonies have often collapsed when introduced in greenhouses for pollination in Japan. We introduce a case of traumatic dislocation of the posterior tibial tendon with avulsion fracture of the medial malleolus in a 52-year-old female patient who was treated surgically with periosteal flap and suture anchor fixation. Arriving at correct conclusions: the importance of association, causality, and clinical significance. A 45-year-old man who had hypertension, hyperthyroidism, and bronchial asthma was admitted to our hospital because of a low-grade fever and chest pain. We aimed to validate these findings in the modern era of PAH treatment and additionally to assess the relation of qR in V1 to PAH severity.

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This second case responded well to surgical tenotomy but tissue biopsies were not obtained to permit microscopic assessment of the underlying pathologic process. Diabetic neuropathy in visceral organs such as the gastrointestinal (GI) tract is still poorly understood, despite that GI symptoms are among the most common diabetic complications. Early detection of kidney dysfunction is important to improve risk stratification of atherosclerotic disease. 57 patients (48 men, 9 women, mean (SD) age 46 (7) years who required surgical treatment of chronic alcoholic pancreatitis between January 1977 and October 1995. CT and MR imaging have an important role in establishing the diagnosis of mesenteric ischemia. Specifically during mitosis, we found novel actin-containing structures (mitosis-specific dynamic actin structures, MiDASes) underneath the nuclei and centrosomes. Clinicopathological study of recurrent uterine cervical squamous-cell carcinoma. Bradykinin generation may explain hypotension during LDL apheresis observed in patients taking angiotensin converting enzyme (ACE) inhibitors. In particular, the seasonal patterns in temperature-related deaths will be shifted. These studies have fundamentally changed diamox dose altitude sickness our view about the endocytotic role of caveolae.

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Data were systematically obtained on 1520 patients admitted to 75 UK hospitals between May 2009 and January 2010. To examine whether perceptual grouping on the basis of orientation can be performed simultaneously with or only subsequently to grouping according to colour or luminance, we tested whether subjects are able to segregate arrays of texture elements that differ from surrounding elements by conjunctions of either (i) colour and orientation, or (ii) luminance contrast and orientation, or (iii) luminance contrast polarity and orientation. The current study assessed for changes in peak oxygen uptake during cardiopulmonary exercise testing after CTO-PCI. Effectiveness and safety of 30 mg versus 40 mg stavudine regimens: a cohort study among HIV-infected adults initiating HAART in South Africa. Chronic administration of high doses of ND can alter serum FSH, LH and testosterone and hematological parameters in male rats. Correlation of brain uptake with the relative density of mGluR1 transcript allows specific receptor binding of a radioligand to be quantified without injecting pharmacologic doses what happens if you take 20 mg of zyrtec of a blocking agent. Abundant decidual IGFBP-1 may interact with the IGF-II-expressing, protease-secreting trophoblast to modulate invasion. Eco-evolution in size-structured ecosystems: simulation case study of rapid morphological changes in alewife. In vitro treatment with a Jagged1 agonist peptide modulated the T-cell activation network in PBMCs from patients with MS. In conclusion, an effective therapy may be possible using hepatic arterial infusion chemotherapy of cisplatin in patients with biliary cystadenocarcinoma for whom surgical treatment is not suitable.

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