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Alpron (Alprazolam)
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Alpron

Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alpron, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alpron is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alfresh, Alpam, Alpramax, Alprocalm, Alprotame, Alzolite, Alzopax, Alzotime, Ambulax, Anxit, Azicalm, Cooltime, Depten, Endolam, Ezoprax, Fledore, Kaprolam, Kurelam, Luzarn, Nitril, Normatine, Optizole, Plxna, Prolam, Prozam, Prozolam, Synozolam, Tenfree, Welnorm, Zolin

Similar Products:
Retin, Mobic, Fosamax, Prilosec, Clozaril, Lamictal, Myambutol

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results.

Do not crush, chew, or break an extended-release tablet. Swallow the pill whole. It is specially made to release medicine slowly in the body. Breaking the pill would cause too much of the drug to be released at one time.

Measure the liquid form of Alpron with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not swallow the orally disintegrating tablets whole. Allow it to dissolve in your mouth without chewing.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

You may have seizures or withdrawal symptoms when you stop using Alpron. Ask your doctor how to avoid withdrawal symptoms when you stop using Alpron.

Keep track of the amount of medicine used from each new bottle. Alpron is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alpron are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Some products that may interact with this drug include: kava, sodium oxybate.Other medications can affect the removal of Alpron from your body, which may affect how Alpron works. Examples include azole antifungals (such as itraconazole, ketoconazole), cimetidine, certain anti-depressants (such as fluoxetine, fluvoxamine, nefazodone), drugs to treat HIV (delavirdine, protease inhibitors such as indinavir), macrolide antibiotics (such as erythromycin), rifamycins (such as rifabutin), St. John's wort, drugs used to treat seizures (such as carbamazepine, phenytoin), among others.Tell your doctor or pharmacist if you also take drugs that cause drowsiness such as: certain antihistamines (such as diphenhydramine), medicine for sleep or anxiety (such as diazepam, zolpidem), muscle relaxants, narcotic pain relievers (such as codeine), psychiatric medicines (such as chlorpromazine, risperidone, amitriptyline, trazodone).Check the labels on all your medicines (such as cough-and-cold products) because they may contain ingredients which cause drowsiness. Ask your pharmacist about the safe use of those products.Cigarette smoking decreases blood levels of this medication. Tell your doctor if you smoke or if you have recently stopped smoking.

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Prognostic factors effective on survival of patients with glioblastoma: Anadolu Medical Center experience. Bedside emergency department ultrasonography availability and use for blunt abdominal trauma in Canadian pediatric centres. Given the effects of low concentrations of oxLDL on osteoblast functions, oxLDL may contribute to the impairment of bone remodeling equilibrium. NAC inhibition of the assays investigated typically occurs at concentrations higher than expected during IV and oral NAC therapy. This review presents evolving applications of HDAC inhibitors as potential drugs in neurological research and therapy. Independent variables were converted into residual change scores (between time 1 and time 2) and their influence on caregiver gains at time 2 and time 3 was examined. In the atrioventricular (AV) valves and the fibrous heart skeleton isolating atrial from ventricular myocardium, EPDCs colocalize with periostin, a matrix molecule involved in remodeling. It is anticipated that this development will provide impetus to the discipline by promoting training programs, the creation of neuropsychology posts, wider service delivery, and increased research funding. Recent advances in column heating technology have made possible very fast linear temperature programming for high-speed gas chromatography.

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A Comparison of Theory-Based and Experimentally Determined Myocardial Signal Intensity Correction Methods in First-Pass Perfusion Magnetic Resonance Imaging. ESCRT and ESCRT-associated proteins are required during the assembly and release of many RNA viruses, including HIV. We find that, for an Ising spin chain coupled to a bosonic bath and driven by a monotonically decreasing transverse field, excitation diffusion sharply slows down below the quantum critical region. The seroprevalence of hepatitis A and B in people testing positive for hepatitis C. These observations explain the lack of transthyretin deposition in transgenics carrying a low copy number of human transthyretin genes. Funding for Project 2000 courses in London has been confirmed following uncertainty over nurse education caused by the Tomlinson report. N2-N3 neck nodal control without planned neck dissection for clinical/radiologic complete responders-results of Trans Tasman Radiation Oncology Group Study 98.02. The two-dimensionally perforated WO3 layer was fabricated by use of colloidal lithography. Interpreting and evaluating the CASP-19 quality of life measure in older people.

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There were, however, marked social class differences on all three, with working-class children tending to lean towards poorer social adjustment than their middle-class peers. Chronic Obstructive Pulmonary Disease (COPD) is increasingly recognized as a leading cause of global morbidity and mortality. Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies. The results obtained in our model system could be useful in clarifying the mechanisms of the myelinating and demyelinating processes that take place in the natural membrane. Ongoing epidemic of Mycoplasma pneumoniae infection in Jerusalem, Israel, 2010 to 2012. The attachment to highly adhesive IOLs was almost 4-fold greater than that to low-adhesive IOLs.

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Long-term effects of traffic-related air pollution on mortality in a Dutch cohort (NLCS-AIR study). The cervical spondylotic myelopathy is the most frequent spinal dysfunction. Presently, randomized, multicenter clinical trials utilizing glutamine as both nutritional replacement and pharmacologic intervention, independent of nutritional needs, are ongoing. General practice volunteers provided screen shots of the clinical coding screen they would use to code a diagnosis or problem title in the clinical consultation. Sufficient muscle perforators arise from the proximal brachial artery and enter the brachioradialis to permit transfer of the muscle with the fasciocutaneous forearm flap as a single free-flap unit. Insular infarct location was determined using the in-house software Stroke Lesion Atlas. Factor VIII mutation spectrum in haemophilia A patients in the population of Henan, China. A high ratio of mRNA expression of receptor activator of NF-kappaB ligand (RANKL)/osteoprotegerin (OPG) in Vehicle synovial tissue was suppressed by COX2L and COX2H. We present the case of a 60year old female with advanced bowel cancer who was admitted with seizures and sub-arachnoid haemorrhage, with radiographic features of PRES, shortly after receiving bevacizumab (Avastin), a VEGF-inhibitor.

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Paracellular ion transfer in kidney and tissues and its pharmacological regulation. Potential risk factors should be taken into account and clinicians should thus focus on the most vulnerable subgroups. There was good agreement between these findings and the subjective feedback from the patient. Protein degradation proceeds with a decreasing rate of 4-1.5 per cent per h over a 4-h period indicating a comparatively low degradation capacity. The prevalence of pressure ulcers on both the pulmonary and oncology units decreased to zero in the first quarter after the intervention, results that were largely sustained through the end of 2006. Sleep loss impacts the effort-related choices we make and those choices may influence our health and safety. Immune profile of asplenic patients following single or double vaccine administration: A longitudinal cross-sectional study.

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Activity in some regions during resting-state fMRI can be predicted with high accuracy from the activities of other regions. In a search for PI(4)P effector molecules, we performed a screen for synthetic lethals in a background of reduced PI(4)P and found the gene GGA2. Treatment options for metastatic soft-tissue sarcomas are limited. Hypoglycemia is a common metabolic problem in the neonatal period especially in the presence of settings like prematurity, small for gestational age babies and sepsis. This technique has been proven effective in maintaining the soft tissue architecture and allows hard tissue grafting of the fenestration defect around the implant in a postextraction socket. Innate production of tumour necrosis factor alpha and interleukin 10 is associated with radiological progression of knee osteoarthritis. Cutaneous vasoconstriction/vasodilatation occurs in response to whole body and local cooling/heating, and the vasomotor activities play a pivotal role in thermal control of the human body. Interference in ACTH immunoassay negatively impacts the management of subclinical hypercortisolism.

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Our initial controlled studies have shown a beneficial, although temporary, dose-related effect of cladribine on the course of chronic progressive multiple sclerosis. Strikingly, we observed an increased percentage of RBCs retaining mitochondria in SCD patient blood samples compared with healthy individuals. Criteria for quantitative and qualitative data integration: mixed-methods research methodology. Correlation of Molecular Subtypes of Invasive Ductal Carcinoma of Breast with Glucose Metabolism in FDG PET/CT: Based on the Recommendations of the St. The ulcer control group exhibited severe gastric mucosal injury, and this finding was also confirmed by histology of gastric mucosa which showed severe damage to the gastric mucosa with edema and leucocyte infiltration of the submucosal layer. Preserved recovery of cardiac function following ischemia-reperfusion in mice lacking SIRT3. Determination of trigonelline in coffee powder and instant coffee by ultrasonic extraction and high performance liquid chromatography.

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Disturbed synthesis of type II collagen interferes with rate of bone formation and growth and increases bone resorption in transgenic mice. Ss1 and Ss2 involve overlapping sites on beta4 and are competitive, but neither inhibits the interaction with AID. Analysis of affinities between specific biological ligands using atomic force microscopy. Placebo-controlled, double-blind, randomized clinical trial conducted from September 1995 to July 1998 at a general clinical research center. Laparoscopic retroperitoneal lymph node dissection for nonseminomatous germ cell tumors: long-term oncologic outcomes.

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BCP/PLGA was applied into periodontal defects of the upper premolars and upper first molar of the opposite side. A background is described which allows embedding of the quality definitions as well as evaluation methods into a conceptual framework connected to the vision and mission of organic agriculture and food production. Circadian rhythms in the eye: the physiological significance of melatonin receptors in ocular tissues. For example, a large number of positive social relationships and a few conflictual ones may buffer individuals against the adverse effects of SES-related stress. Build a Better Hearing Assessment and the Patients Will Beat a Path to Your Clinic. The four disease conditions include diabetes, heart diseases, gastric ulcers, and chronic obstructive pulmonary disease. In addition, memory T-cells initially exposed to nicotine or ST during a primary immune response, exhibit excessive cytokine expression when T-cells are restimulated in the absence of nicotine or ST.

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The non-visual motor task was not associated with thickness of any region. Acute unilateral pneumonitis in a patient with polymyositis: a unique presentation of polymyositis-associated pneumonitis. A Novel Method for Insertion of the Straight Metallic Tracheal Stent. Once the citations are in hand, physicians have several options to retrieve the full text of the relevant articles. Absence of WASp Enhances Hematopoietic and Megakaryocytic Differentiation in a Human Embryonic Stem Cell Model. We discuss conceptual differences among the various orthology inference methods and databases, and examine the difficult issue of verifying and benchmarking orthology predictions. The molecular mechanism behind reactive aldehyde action on transmembrane translocations of proton and potassium ions. The present study has examined the role of life-style on plasma and erythrocyte membrane lipid profile in 25 adult male gastric cancer patients as well as age and sex-matched controls.

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Minimally invasive techniques, such as laparoscopic appendectomy or minimally invasive thyroid surgery, are thought to produce better cosmetic results. Intent-to-treat analysis for longitudinal clinical trials: coping with the challenge of missing values. Quantitative comparison of minimally invasive and standard cranial approaches remains a methodologic challenge. Building organizational supports for research-minded practitioners. Experiments on both single surface coil and phased array coils are consistent with simulation results.

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Both point-resolved spectroscopy (PRESS) and stimulated-echo acquisition mode (STEAM) sequences were used. In-situ characterization of nanoparticle beams focused with an aerodynamic lens by Laser-Induced Breakdown Detection. The prodrug, sulfanegen sodium, is effective in reversing CN toxicity induced by SNP or NaCN. In extensive simulation studies, we examine the operating characteristics of the proposed method. The authors tested an educational intervention designed to increase use of the Ottawa Ankle Rules, a widely publicized set of clinical guidelines previously shown to reduce the use of radiography for diagnosis of acute ankle injuries. Pain after coronary artery bypass surgery persists for several days.

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Findings supported the fact that stories served as cultural artifacts that describe the cultural pathways of a group of African Americans mothers and daughters. PC may play an essential role in peritoneal integrity and function, the role of PD induced HPMC senescence on PC homeostasis, however, is unknown. Lauroyldextran and crosslinked galactomannan as coating materials for site-specific drug delivery to the colon. The authors sought to investigate the clinical and pathologic features predictive of bony invasion, perineural invasion, or lymphadenopathy in patients that had undergone head and neck imaging for hrSCC. Characterization of the disposition of fostamatinib in Japanese subjects including pharmacokinetic assessment in dry blood spots: results from two phase I clinical studies. Mitochondria are important generators of energy, providing ATP through oxidative phosphorylation. To better understand the brain structure underlying this profile, we compared individuals with Williams syndrome with controls using multimodal neuroimaging data and new analytic methods (diffeomorphic mapping and atlas-based analysis). These results suggest that co-administration of sub-analgesic doses of oxycodone and morphine to patients may provide excellent pain relief with a reduction in opioid-related CNS side-effects.

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Enhancing health management of chronic and non-communicable diseases to improve control effect of hypertension and high blood glucose. The developed approach has shown a very good agreement between the theoretical predictions given by the SBS model and the experimental results. The six subgenus-specific amplimers are distinguishable by agarose gel electrophoresis, and subsequent restriction analysis is not necessary. To investigate the antitumor activity of nanoparticle albumin-bound paclitaxel (nab-paclitaxel) plus S-1 in patient-derived pancreatic cancer xenograft mouse models and to explore biomarkers that could predict drug efficacy. Dogs were screened for breed, size, health, travel history, and previous blood transfusions, and the quality of blood specimens was also reviewed. The biological properties of some herpesviruses such as the ability of latent persistency in the host cells and the presence of viral DNA in atherosclerotic lesions, suggest the possible role of herpesviruses in the development of atherosclerosis. Two auditory event-related potential (ERP) components, the N200 and the cost of aygestin tablet N400, were used to assess discrimination response and word recognition.

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The charts of 21 patients (22 knees) with significant radiographic changes of the patella after total knee arthroplasty were reviewed. Between April 2012 and September 2014, twenty-seven households from across Nchelenge District were randomly selected for monthly light trap collections of mosquitoes. After a wash-out period of 2 weeks, these parameters were assessed in order to quantify the sustained effect of this treatment. Rituals, myths and fashions of nursing care: a follow-up after 30 years and new risky trends. We studied how their serum levels were associated with allergy status, intratonsillar/nasopharyngeal virus detection and intratonsillar expression of T cell- and innate immune response-specific cytokines, transcription factors and type I/II/III interferons in patients undergoing tonsillectomy. Although the need for stability is unquestionable, newer technologies and imaging modalities have allowed improvement in the biology of internal fixation in selected fractures and arthrodeses. To compare the breathing effects on dynamic contrast-enhanced (DCE)-MRI between controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA)-volumetric interpolated breath-hold examination (VIBE), radial VIBE with k-space-weighted image contrast view-sharing (radial-VIBE), and conventional VIBE (c-VIBE) sequences using a dedicated phantom experiment. By presenting the physicians with well-designed case histories, it is possible to extract the clinical knowledge pertinent to analytical quality. Ovarian primordial follicle pool size was significantly decreased with all treatments transgenerationally.

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In this report, we focus on the consequences of controllability and observability on the number of distinct exponential terms in the fluorescence decay and on the identifiability analysis of the photophysical model of intermolecular two-state excited-state processes. Our objective was to evaluate complete unilateral cleft lip and palate repair outcome in the Cleft Unit in Perth, Western Australia, by assessment of dentoalveolar relationships. Overall the results supported the study hypothesis-i.e., medical laboratory professionals on a fixed day shift have lower job content routinization (higher task enrichment) than fixed evening and night and rotating shifts. To explore age and gender differences in the impact of diabetes on the prevalence of ischemic heart disease (IHD) in a defined population. The distances traversed by perforators were significantly reduced with a bifurcating branching pattern of the DIEA, particularly those originating from the lateral branch, and were greatest with a trifurcating branching pattern. Raf-1 kinase inhibitor protein (RKIP) is a tumor and metastasis suppressor in cancer cells.

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