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Alprotame (Alprazolam)

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Alprazolam, available under the trade name Xanax, is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder, but also in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprotame, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprotame is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aaram, Almac, Almee, Alproz, Altalin, Altok, Alzex, Alzopax, Alzoset, Ambulax, Anxico, Anxilam, Anxyl, Benzolam, Censir, Dipra, Finezol, Fluti, Fluxin, Fluzolam, Hipose, Nexlpra, Normatine, Oclam, Onapract, Ozolam, Plxna, Poize, Prazil, Pronil, Proprazolam, Prosanti, Resta, Restyl, Riolam, Selamb, Setlan, Sinzolam, Sozox, Tenlax, Tenolam, Tenschem, Tensfree, Trapose, Trika, Trustin, Visram, Xylonite, Zeprax

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Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


Take this medication by mouth as directed by your doctor. Dosage is based on your medical condition, age, and response to treatment. Your dose may be gradually increased until the drug starts working well. Follow your doctor's instructions closely to reduce the risk of side effects.This medication may cause withdrawal reactions, especially if it has been used regularly for a long time or in high doses. In such cases, withdrawal symptoms (such as seizures) may occur if you suddenly stop using this medication. To prevent withdrawal reactions, your doctor may reduce your dose gradually. Report any withdrawal reactions immediately.Along with its benefits, this medication may rarely cause abnormal drug-seeking behavior (addiction). This risk may be increased if you have abused alcohol or drugs in the past. Take this medication exactly as prescribed to lessen the risk of addiction.When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.Tell your doctor if your condition persists or worsens.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprotame XR dosage information

Side effects

The most common side effects associated with Alprotame are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Alprotame XR if you have:

narrow-angle glaucoma; if you are also taking itraconazole (Sporanox) or ketoconazole (Nizoral); or if you are allergic to alprazolam or to other benzodiazepines, such as chlordiazepoxide (Librium), clorazepate (Tranxene), diazepam (Valium), lorazepam (Ativan), or oxazepam (Serax).

Before taking Alprotame XR, tell your doctor if you are allergic to any drugs, or if you have:

asthma, emphysema, bronchitis, chronic obstructive pulmonary disorder (COPD), or other breathing problems; glaucoma; kidney or liver disease (especially alcoholic liver disease); a history of depression or suicidal thoughts or behavior; or a history of drug or alcohol addiction.

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

It is dangerous to try and purchase Alprotame XR on the Internet or from vendors outside of the United States. Medications distributed from Internet sales may contain dangerous ingredients, or may not be distributed by a licensed pharmacy. Samples of alprazolam purchased on the Internet have been found to contain haloperidol (Haldol), a potent antipsychotic drug with dangerous side effects. For more information, contact the U.S. Food and Drug Administration (FDA) or visit

FDA pregnancy category D. Alprotame XR can cause birth defects in an unborn baby. Do not use Alprotame XR without your doctor's consent if you are pregnant. Tell your doctor if you become pregnant during treatment. Use an effective form of birth control while you are using this medication. Alprazolam can pass into breast milk and may harm a nursing baby. Do not use Alprotame XR without telling your doctor if you are breast-feeding a baby.

The sedative effects of Alprotame XR may last longer in older adults. Accidental falls are common in elderly patients who take benzodiazepines. Use caution to avoid falling or accidental injury while you are taking Alprotame XR. Do not give this medication to anyone under 18 years old.

Alprotame XR pregnancy and breastfeeding warnings (more detail)

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Two molecular forms of gonadotropin-releasing hormone (GnRH-I and GnRH-II) are expressed by two separate populations of cells in the rhesus macaque hypothalamus. These effects should also be considered in the ablative applications. Fluence-to-absorbed-dose conversion coefficients for neutron beams from 0.001 eV to 100 GeV calculated for a set of pregnant female and fetus models. Impacts of road network expansion on landscape ecological risk in a megacity, China: A case study of Beijing. Fifty patients referred for endoscopic evaluation of dysphagia between January 2002 and March 2005. Both inflammation and obesity are risk factors for AF, and adipose tissue is a known contributor to systemic inflammation. This may impact the development of oral tissues, as manifested by enamel hypoplasia, palatal distortion, malocclusion, or delay in tooth eruption and maturation. The findings from existing research on the association between socioeconomic status (SES) and multiple sclerosis (MS) are inconsistent.

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Cell proliferation and apoptosis in urinary bladder urothelium of rats following ovariectomy and chronic estrogen replacement therapy. For larger children, several adult MCSDs may be suitable, including the Abiomed BVS-5000, Thoratec, HeartMate and DeBakey MCSD. KNO3 was introduced as inorganic mineralizer to direct the growth of beta-MnO2 3D nanostructures from Mn(NO3)2 solutions. This was then used as template for PCR with three sets of primers, targeting the 16S rRNA genes of Spirochaetes, Bacteroidetes and the domain Bacteria. Physical functioning and health-related quality-of-life changes with exercise training in hemodialysis patients. This study uncovers a novel function of Brucella DNA, which can help us further elucidate the mechanism of Brucella intracellular survival. To investigate the feasibility and effectiveness of LTBI screening in a community college. Both paracervical and mucosal blocks have been shown to provide relief from the pain and cramping associated with cryosurgery. Complementary PTM Profiling of Drug Response in Human Gastric Carcinoma by Immunoaffinity and IMAC Methods with Total Proteome Analysis. We also searched the Proceedings of the American Society of Clinical Oncology (1986 to August 2016).

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Quantitative prediction of metabolic inhibition of midazolam by erythromycin, diltiazem, and verapamil in rats: implication of concentrative uptake of inhibitors into liver. Nano-LC-ESI MS/MS analysis of proteins in dried sea dragon Solenognathus hardwickii and bioinformatic analysis of its protein expression profiling. Subsequently, scintillation counting and autoradiography were employed to study retinal protein metabolism using leucine uptake as an index. This need has been the centre of controversy for critical care units for many years. Other stresses induce the release of cytochrome from mitochondria and caspase activation. In two replicate populations, sexual selection was removed through enforced monogamous mating with random mate assignment or retained in promiscuous controls. The LuxR-type regulatory protein, VjbR, and an N-acylhomoserine lactone signaling molecule are both involved in regulating expression of the virB-encoded type IV secretion system. Issues concerning the impact of hydrodynamic slip and the role of diffuse interfacial structures are discussed. Green fluorescent protein and Lac-Z-transfected hAFSCs were microinjected into murine embryonic kidneys (12.5-18 days gestation) and were maintained in a special co-culture system in vitro for 10 days.

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Critical care in the near future: patient-centered, beyond space and time boundaries. Hausdorff distance based 3D quantification of brain tumor evolution from MRI images. After one course what does the drug actos do of this combined chemotherapy, the tumor was further reduced in size and became difficult to discern on abdominal computed tomography (CT). Ultrasound-modulated optical tomography (UOT) is a technique that images optical contrast deep inside scattering media. The preventive maintenance program instituted at Camden-Clark Memorial Hospital (Parkersburg, West Virginia) aids in the efficient and safe use of medical electronic instrumentation in the general- and critical-care areas of the hospital.

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Urinary diversion after cystectomy in old and high risk patients is associated with major complications, exspecially those related to the type of urinary diversion. The purpose of this study was to review our experience with ALGBs and to determine any differences between limited colon resection (LCR) and total/subtotal colon resection (TCR). The IgA1-depleted saliva samples were subsequently tested for neutralizing capacity in a PBMC-based neutralization assay using a primary HIV-1 clade A isolate to determine biological relevance of the measured molecules. Capecitabine is effective and indicated for the salvage treatment of metastatic breast cancer. High proportion of known abdominal aortic aneurysm in patients with rupture indicates surveillance deficiency. To test whether a curriculum-based advocacy training programme improves advocacy behaviour when compared to a matched group engaged in self-directed advocacy activities. Utilizing evidence-based practice (EBP) guidelines affords the best avenue for providing safe and effective treatment of HTN. The effect of cortisone on populations of Ostertagia ostertagi of uniform age.

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Mechanical corneal epithelium scraping and ethanol treatment up-regulate cytokine gene expression differently in rabbit cornea. Physiotherapists identified significant differences in the provision of musculoskeletal physiotherapy services across primary care sites. Patients were randomly assigned to continued usual care or one of two interventions: feedback only and feedback plus care management. Surveillance of 75 immunodeficiency patients exposed to UK-sourced immunoglobulin, including batches derived from donors who went on to develop vCJD, has not detected any clinical cases of vCJD, or of asymptomatic infection in 15 patients with available tissue samples of sufficient quality for testing. Preliminary report of tolvaptan treatment in Japanese patients with heart failure. Data from 14,029 patients aged 65 years and older were evaluated using patient information from Veterans Administration and Medicare databases. Comprehensive analysis included chromosomal aberrations as well as whole exome and transcriptome sequencing, and the candidate driver genes for malignant transformation were validated with public database. Here, we describe the effective expression system and purification procedure for preparative-scale production of transmembrane peptides from four representatives of ErbB family, ErbB1, ErbB2, ErbB3, ErbB4, for structural studies. Fifteen participants were tested on a sequencing task while eye and hand movements were recorded binocularly using a video-based eyetracker and a motion capture system.

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Antioxidant and cytotoxic activities of canadine: biological effects and structural aspects. One- what does lexapro come up as on a drug test year trial of the antipsychotic acridan compound, SK AND F 14336. Program implementation was associated with reduced LOS among older inpatients with delirium. Structural magnetic resonance imaging was used to determine hippocampal brain volumes in the same subjects. ROC1 and APC11 immunocomplexes can catalyze isopeptide ligations to form polyubiquitin chains in an E1- and E2-dependent manner. Risky business: Lived experience mental health practice, nurses as potential allies. However, several lectins showed a strong preference for bladder cell line glycans over serum glycans and are potentially useful for enriching glycoproteins originating from the urothelium in urine. Comparative trial assessing suture techniques and types of urinary catheters in vesicourethral anastomotic tensile strength in a porcine model.

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