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Altiazem (Diltiazem)

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Altiazem is a benzothiazepine derivative with antihypertensive and vasodilating properties. Approved in 1982 by the FDA, it is a member of the non-dihydropyridine calcium channel blockers drug class. It works through various mechanisms of action, but it primarily works by inhibiting the calcium influx into cardiac and vascular smooth muscle during depolarization.

Other names for this medication:
Altiazem, Angizem, Cardem, Cardiorex, Cartia, Coriem, Dicard, Dilacor, Dilcardia, Dilcontin, Dilcor, Dilgard, Dilocor, Dilter, Diltia, Diltiaz, Diltiazem, Dilticard, Diltime, Diltp, Dilzem, Heartil, Icidil, Ionozem, Kaizem, Masdil, Onzem, Taztia, Tiamate, Tiazac

Similar Products:
Combivent, Danocrine, Remeron, Addyi, Rebetol

Also known as: Diltiazem


Diltiazem is used to control rapid heartbeats or abnormal heart rhythms. It belongs to a group of drugs called calcium channel blocking agents. Diltiazem affects the movement of calcium into the cells of the heart and blood vessels. As a result, the heart beats slower and the blood vessels relax, thus, increasing the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


Take Altiazem exactly as prescribed by your doctor. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Do not crush, chew, break, or open an extended-release tablet or capsule. Swallow it whole.

Use Altiazem regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.

You should not stop using Altiazem suddenly. Stopping suddenly may make your condition worse.

If you are being treated for high blood pressure, keep using this medicine even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medicine for the rest of your life.

Your blood pressure will need to be checked often. You may also need frequent blood tests.

Store Altiazem at room temperature away from moisture and heat.

Detailed Altiazem dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of diltiazem can be fatal.

Overdose symptoms may include slow heartbeat, weakness, chest pain, shortness of breath, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Altiazem if you are allergic to diltiazem, or if you have:

a serious heart condition such as "sick sinus syndrome" or "AV block" (unless you have a pacemaker); very low blood pressure; or if you have recently had a heart attack and you have a build-up of fluid in your lungs.

To make sure Altiazem is safe for you, tell your doctor if you have:

kidney disease; liver disease; congestive heart failure; or if you also take digoxin, or a beta blocker (such as atenolol, carvedilol, metoprolol, propranolol, sotalol, and others).

It is not known whether Altiazem will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Diltiazem can pass into breast milk and may harm a nursing baby. You should not breastfeed while using this medicine.

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These results suggest that, beyond lipid model of atherosclerosis, age-related processes affecting resistin blood levels may also be involved in the late development of AS. Relationship between the functional status of the reticuloendothelial system and the outcome of experimentally induced pancreatitis in young mice. The newer agents offer many options in the treatment of epilepsy that are safe, efficacious, and well tolerated. In this study, markers of immune escape including regulatory T cells (T(regs)), dendritic cells (DCs), and TGF-beta were evaluated in 14 Stage IV melanoma patients and correlated with survival. elegans, as well as to study physiological and developmental processes that will provide molecular insight on DAF-18/PTEN function.

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Thrombin generation induced by tissue factor plus ADP in human platelet rich plasma: A potential new measurement to assess the effect of the concomitant use of an oral factor Xa inhibitor edoxaban and P2Y12 receptor antagonists. IVF treatment is associated with a reduced risk of hospital mental health admissions in women after unsuccessful infertility treatment. To develop the questionnaire, we selected eight items from the most widely used questionnaires in English using the criteria of a group of experts. Significance of reactive oxygen species in distal flap necrosis and its salvage with liposomal SOD. the coordination number) but also to characteristics of the bead size distribution, when given the same sample preparation and confining pressure.

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Plasminogen activator activity in human prostate and breast tumors: relationship to steroid receptors. In this study, we asked whether neuronal activity induced in vivo by application of kainate can induce lasting changes in mossy fiber short- and long-term plasticity. The differential expression of all 8 genes selected for digital polymerase chain reaction validation was confirmed. Consistent with their vascular-modulating function, the dual therapies enhanced morphological normalization of vessels. Protective role of endogenous nitric oxide (NO) in lipopolysaccharide--induced pancreatic damage (a new experimental model of acute pancreatitis). The nature of the immobilized anti-alpha-fetoprotein sheets was examined by measuring the enzyme activity in an antibody-antigen complex reaction. In this study, a proteomics-based method was developed to determine the specificity of kinase by taking the advantages of proteome-derived peptide libraries and quantitative proteomics. This article presents an updated overview of intravenous fluid therapy for calves, recent insights into the development of metabolic acidosis in young calves resulting from accumulation of D-lactate, a simplified algorithm for intravenous fluid therapy, and a procedure for ear vein catheterization under field conditions.

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Sex, race and age differences in muscle strength and limitations in community dwelling older adults: Data from the Health and Retirement Survey (HRS). To model accurately concentrated ionic solutions, the parameters of the potential functions are optimized to reproduce osmotic pressure data. Pharmaceutical companies were contacted for the provision of unpublished seizure-free data in the patients who completed the entire study. We analyzed the abundance, distribution, and function of PPAR-gamma in epithelial cells isolated from the murine proximal and distal colon. Considering risk vs benefit, we therefore believe that the surgical treatment can be offered in most cases as the first treatment option for pineal tumors. A major issue, still debated, is the way to correlate the experimental findings with blood damage. To evaluate the acoustic effect after canal wall-down tympanoplasty with sectioning of the tensor tympani muscle (TTM) tendon in patients with chronic otitis media.

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Multiple superficial white nodules on the bilateral helical rims. Q289P mutation in the FGFR2 gene: first report in a patient with type 1 Pfeiffer syndrome. After 4-level fusion using L1 as the upper instrumented vertebra, proximal vertebral body fractures were found along with the right pedicle fractures of L1 in both cases. When pH was adjusted the efficiency of nitrite denitrification was identical as for nitrates (166.3 mg N/l/h). Elastomeric microparticles for acoustic mediated bioseparations. We thus investigated signaling pathways involved in antioxidant defense mechanisms. We conclude that CCCPR does not augment arterial pressure in the clinical situations associated with decreased LVEDV and is unlikely to provide organ perfusion for trauma victims. gondii oocysts in the environment or after exposure to disinfectants, and therefore their potential infectivity to humans and animals. Complications were identified radiographically in 11 of the 14 patients. Endocrine response to thyroliberin administration in duodenal ulcer.

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The rheological response of interfaces stabilized by 11S-STE mixtures also differed significantly from the response for 11S fibril-peptide-STE mixtures. The 1979 study of credentialing in nursing recommendations: where are we now?. The authors review the relevant literature and present four clinical examples. Our previous study indicated that the combined effect of two intronic single nucleotide polymorphisms (SNPs), which are located in the catechol-O-methyltransferase (COMT) and aldehyde dehydrogenase 3B1 (ALDH3B1) genes, respectively, conferred genetic risk to paranoid schizophrenia. Platelet count (P1), activated partial thromboplastin time (A-PTT), prothrombin time (PT) and plasma fibrinogen levels (Fng) were measured before and after OLT. Description of five new species of Cnemomis, with a key to the known species (Hemiptera: Heteroptera: Coreidae: Discogastrini). We used a population-based cross-sectional study design and analyzed our results using multivariable regression models. Production and characterization of a trehalolipid biosurfactant produced by the novel marine bacterium Rhodococcus sp., strain PML026. Common buzzards (Buteo buteo) bio-indicators of heavy metals pollution in Sicily (Italy).

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A silver-staining method is used and compared to the radioisotope method with results that indicate a superior definition and more accurate evaluation of microleakage. For various spin-echo (SE) sequences, the signal from synovial fluid containing different concentrations of the two contrast agents was calculated. Because the transcription factor signal transducer and activator of transcription 3 (STAT3) has been closely linked with tumorigenesis, we investigated the effect of this vanilloid on the STAT3 pathway in human multiple myeloma cells. Clarifying the role of fine-needle aspiration cytologic evaluation and frozen section examination in the operative management of thyroid cancer. A total of 671 cases of newly diagnosed CHD, 339 CHD deaths and 6255 all-cause deaths occurred between the baseline questionnaire (1990-4) and the end of follow-up in January 2004. The rutin content in amaranth ranged from 0.08 (in seeds) to 24.5 g/kg dry matter (in leaves). The median survival time was 37.6 and 26.3 weeks for patients with limited and extensive disease, respectively (p less than 0.05), and 29.9 weeks for the whole group. The implications of these characteristics for the diagnosis of hoarding are discussed.

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Here we identify a histone H3 endopeptidase activity in Saccharomyces cerevisiae that may regulate these events. Twenty-seven survivors and 28 caregivers participated in MFGT for 12-18 mos. Because ciliogenesis in invertebrates is limited to a very small number of specialized cell types, the role of cilia in developmental signaling pathways is likely a uniquely vertebrate phenomenon. Sequence analysis demonstrated varying homologies with TnC complementary DNA clones isolated from developing chick skeletal muscle. The bacteria found were as follows: Streptococcus pneumoniae (24), Haemophilus influenzae (19), Staphylococcus aureus (12), Streptococcus pyogenes (7), Branhamella catarrhalis (3), and 18 Gram negative bacilli (including 7 Pseudomonas aeruginosa and 11 enterobacteriaceae). The STAT5-GATA2 pathway is critical in basophil and mast cell differentiation and maintenance. Twenty patients with isthmic ectopic pregnancies were selected for treatment by one of three operative modalities. The 2DG uptake was either unchanged or decreased in the ventral horn. Plasma beta-thromboglobulin in uncomplicated insulin-dependent diabetes at rest and during physical exercise.

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Gene expression from the imprinted Dio3 locus is associated with cell proliferation of cultured brown adipocytes. The antibiotic concentration was determined in the serum as well as in the prostate adenoma tissue using microbiological methods after treating the tissue in a stomacher. The new method showed good repeatability and reproducibility and is an important step in the development of alternatives to the animal tests currently in use for shellfish toxin analysis. We conclude that Octreotide prevents the haemodynamic changes following food ingestion, probably by inhibiting the release of those gastrointestinal peptides that induce splanchnic vasodilatation. Sympathetic nerve activity related to local fatigue sensation during static contraction. Thoracic radiographs and ultrasound showed multiple mediastinal nodules and marked pleural effusion, respectively. A frequently proposed mechanism underlying the link between maternal prenatal stress/anxiety and child outcomes is heightened concentrations of maternal cortisol. In contrast, from 18 weeks until term, tracheal submucosal glands contained scattered cells which immunostained for immunoreactive human epidermal growth factor but which did not appear to be classical mucous cells.

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In addition, this study reports a positive activity of epidermal growth factor on porcine adipocyte differentiation that is in clear contrast with previous works performed with rodent cells. A manganese(IV)/iron(III) cofactor in Chlamydia trachomatis ribonucleotide reductase. A ratio of eye to brain activity was used to eliminate errors associated with absolute counting. Ambulatory consolidation chemotherapy for acute myeloid leukemia with antibacterial prophylaxis is associated with frequent bacteremia and the emergence of fluoroquinolone resistant E. We describe a patient with a highly unusual appearance of pyoderma gangrenosum. The cardiovascular effects of vasopressin after haemorrhage in anaesthetized rats.

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We propose a method for generating arc length correspondences across hemispheres, enabling a TBM study of interhemispheric diffusion asymmetries in the arcuate fasciculus (AF) and cingulum bundle (CB). Further dissection by mutation of individual amino acid residues in Lhca4 showed the importance of a serine, phenylalanine, and histidine (S88, F95, H99) for LHCI-730 assembly. We define a measure that represents the ability of alleles to perform well across different combinations and, using numerical iterations within a classical population-genetic framework, show that selection in the presence of sex favors this ability in a highly robust manner. Neither PA200ii nor PA200iii appears to associate with proteasomes. The purpose of this study was to assess the initial effects of a behaviour independent financial incentive on the volume of drug prescribing of general practitioners (GPs). TTC fusion is considered by many as side effects of elavil 25 mg a salvage operation resulting in a stiff ankle and hindfoot, considerably limiting global foot function. Therefore we changed our operative procedure in patients with central bile duct carcinomas performing the reconstruction of intestinal bile drainage by a cholangio-duodenal interposition of a 25 cm jejunal segment. Two-group randomised, parallel trial of cognitive and exposure therapies for problem gambling: a research protocol.

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Ocular injection of retinal S antigen: suppression of autoimmune uveitis. Associations Between Pain, Current Tobacco Smoking, Depression, and Fibromyalgia Status Among Treatment-Seeking Chronic Pain Patients. A patient with a disruption in phonological storage showed good comprehension for many sentences, but was impaired when a difficult syntactic structure was encountered early in a sentence. The present findings emphasize the importance of repeated EEG examinations in the differential diagnosis of the various types of pathophysiological conditions of CHS. Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach. 204 disease free breast cancer patients after mastectomy were intensively monitored with serial serum determination of CEA, CA15.3 and TPA.

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In addition, by analyzing the isotransferrins a rare genetic abnormality can be detected. The threshold temperature (T0) and the thermal constant (K) were estimated using linear regression to be 4.7 degrees C and 207.7 DD, respectively. The effects of neonatal thyroidectomy and thyroid hormone replacement therapy on the development of serotonin-containing neurons in discrete rat brain nuclei were studied. We devise a new, two-level discrete-particle model to simulate ordered colloidal structures with vastly different scales. The question was raised as to whether the opposite process, i.e. The next obvious candidate would be an anticoagulant protein(s) to deal with the dysregulated coagulation that is almost invariably associated with roxithromycin and penicillin allergy xenograft rejection. Differences in IFN production were also observed among BCG-sensitized mice of all four strains upon injection with PPD, C57BL/6 mice engendered the highest levels of IFN, while the C3H/He and DDD mice were intermediate in their response, with the BALB/c mice producing the least amount of IFN. He had undergone right nephrectomy for renal cell carcinoma 11 years ago and right lobectomy for pulmonary metastasis 10 years ago.

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p300 and p300/cAMP-response element-binding protein-associated factor acetylate the androgen receptor at sites governing hormone-dependent transactivation. Moreover, evidence of inconsistent mediation indicated that single-sex testing environments negatively predicted mindset but positively predicted mathematical performance. The alpha-amylase gene was shown to be present in a 2.3-kb insert. In this review, we shall (i) describe the characteristics of apoptotic cell death with particular emphasis on the heart, (ii) discuss the IGF system with emphasis on the cardiac actions of IGF-I under normal and pathological conditions, (iii) elaborate on the potential role of IGF-I in myocardial protection, and finally (iv) describe how an improved understanding of the cardiac actions of IGF-I may lead to better protective clinical strategies in the future. Despite mixed results in smaller cohorts, large multicentre analyses consistently identify an association between postoperative complications and long-term mortality. Eventually, pathway enrichment analysis for candidate genes was performed. It can easily be distinguished by less sculptured elytra, its differently shaped antennal scrobe, and by the pronotum not constricted anteriorly and expanded over the head. Teaching nurses priority setting for patients with pain of acute myocardial infarction.

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Two laboratory strains of malignant catarrhal fever virus were readily adapted to and maintained by passage in Vero cells. Comparison of intestinal calcium absorption and circulating 1,25-dihydroxyvitamin D levels in malignancy-associated hypercalcaemia and primary hyperparathyroidism. The isolated enzyme does not clot human fibrinogen and when mixed with normal plasma generates activity of Protein C. The NORs were not observable during the first cleavage division. Head and neck zyrtec drops infant dosage cancer: dedicated FDG PET/CT protocol for detection--phantom and initial clinical studies. Seventeen cases have already been published and 7 other cases diagnosed recently in Bamako or Marseille are reported here. Extensions of current capabilities will be the integration of higher order dimensionality, such as rotation and deformation in addition to translation, into the estimate of the patient pose and real-time reoptimization and adaption of delivery to the dynamically changing anatomy of cancer patients. Biochemical and histochemical studies have shown the presence of various carbohydrates in enamel.

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The exact number of immunized persons and the total number of registered patients are still unknown, but it is certain of being unjustifiably low. At age 11 years, a muscle biopsy was performed in the deltoid muscle for neuromuscular junction sampling. An ecdysteroid-inducible insulin-like growth factor-like peptide regulates adult development of the silkmoth Bombyx mori. Both treatment modalities were successful in moving the maxilla rulide tablets 150mg side effects forward, proclining the maxillary incisors and retroclining the mandibular incisors. The aim of this paper is to review the imaging findings of the whole spectrum of stress-induced bone lesions of the leg in athletes. We present a retrospective cohort study in a medical intensive care unit (ICU) of a university hospital that serves as a tertiary care center. With a vision-reversal combination (5 degrees turntable and 10 degrees screen oscillation), there was no change in the gain of the HVOR, but a moderate advancement in the phase.

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Disease activity, pain intensity (Visual Analogue Scale, VAS), bodily pain (BP) in the 36-item Short Form Health Survey (SF-36), activity limitations (Health Assessment Questionnaire, HAQ), and medication were reported at inclusion and at follow-up after 1, 2, and 3 years. For similar cases involving pericardial schwannomas, complete surgical resection is recommended, particularly for the prevention of life-threatening cardiopulmonary complications. Production of carboxylates from high rate activated sludge through fermentation. Stimulation of hMS cell nodule formation by osteoclast conditioned media was attenuated by the Wnt antagonist Dkk1, a BMP6-neutralizing antibody, and by a S1P antagonist. Eighty per cent of clones from this library (total yield 20,000) identify single-copy DNA sequences. The main conclusion is that the commonly used approximate equations provide reasonable, but not perfect, estimates of the isosteric heats of liquid adsorption using only the experimental adsorption isotherms. In patients with NSTE-ACS and normal cTnT- aristocort cream review hs, a planned early invasive treatment strategy was associated with increased rates of procedure-related MI and bleeding but no differences in long-term spontaneous MI, non-procedure-related bleeding or mortality. Our data suggest that OPCAB is a safe alternative to on-pump CABG in dialysis patients. A gene for the major cytoplasmic tRNATyr from Nicotiana rustica contains a 13 nucleotides long intron.

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During the first two days the epithelium bactrim dose renal grows over the exposed stroma regenerating a complete epithelial lining. Bacterial communities in thermophilic H2-producing reactors investigated using 16S rRNA 454 pyrosequencing. The research team aimed to evaluate the acute effects on HRV of selected auditory stimulation by 2 musical styles, measuring the results using nonlinear methods of analysis: Shannon entropy, symbolic analysis, and correlation-dimension analysis. Vaccination should be administered to the patients with inflammatory bowel disease with the caution of its possible side effects. Molecular genetic studies suggest a mechanism by which the clinical association of progressive white matter disease and NF1 might arise.

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