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Amarkor (Nifedipine)
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Amarkor

Amarkor is a dihydropyridine calcium channel blocker. Amarkor is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Amarkor was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Amarkor works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Afeditab, Amarkor, Aprical, Calchan, Cardicon, Cardipin, Cardules, Chronadalate, Conducil, Cordalat, Corotrend, Farmalat, Fenamon, Menoprizin, Milfadin, Nedipin, Nelapine, Nidilat, Nifecard, Nifecardia, Nifedical, Nifedicor, Nifedipine, Nifedipino, Nifedipinum, Nifelong, Nifin, Nilol, Nirena, Noviken, Zenusin

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Amarkor. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Amarkor and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Amarkor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Adalimumab trough level and PASI score at the time of serum sampling to determine the receiver-operator characteristics analyses and concentration effect curve. We studied the response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) of mouse hepatoma cells that contain a single, integrated copy of a chimeric gene under the control of a dioxin-responsive DNA domain, which was originally associated with the cytochrome P450iA1 gene. The enhancing effect of dextran sulfate (DS) on delayed hypersensitivity to nonviable Mycoplasma pulmonis in mice was evaluated by means of delayed footpad swelling. An active shielding technique can reduce the contamination of environmental magnetic noise in the frequency range below 10 Hz. We also demonstrate that the endogenous ABA level in the leaves increased only when the leaves themselves were exposed to drought stress, suggesting that leaves play a major role in the production of ABA in response to acute water shortage. Significant increment in the semen parameters was noticed in animals that received a lower dose of the plantain flour, but those animals who received the high dose had marked and very significant reduction in sperm cell concentration and percentage of morphologically normal spermatozoa. CBT appears to be associated with reductions in hopelessness in people with co-occurring depression and alcohol misuse, even when it is not the focus of treatment. In occluded hemisphere of MCA-occluded rats, catecholamine levels were decreased and ratios of deaminated metabolite to corresponding monoamine were increased compared with the respective values of the sham-operated group, and these changes were reversed by T-794. RA was ascertained by at least 3 visits using ICD-9 code 714.0, plus at least 2 visits with prescription of antirheumatic drugs in a period of 12 months.

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The immune restorative effect of Isoprinosine administration on the local graft-versus-host reaction of cancer patients. A randomized double blind crossover placebo-controlled clinical trial to assess the effects of a mouthwash containing chlorine dioxide on oral malodor. After each treatment, the behaviour of the rats was automatically monitored using the so-called LABORAS method, which discriminates between grooming, locomotion and inactivity. The introduction in 2000 of the 7-valent pneumococcal conjugate vaccine and penicillin prophylaxis for children with SCD has greatly reduced the incidence of IPD in this population. Based on rodent studies, group II metabotropic glutamate receptors (mGluR2 and mGluR3) were suggested as targets for addiction treatment. However, complement and CRP have not been investigated on a tissue level locally at the site of the burn trauma. Participants answered questions related to FN risk assessment and G-CSF use as secondary prophylaxis (SP) and for the management of FN.

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Identification of sulfur groups in the outer plexiform layer of the newt retina. A marginal zone-B cell lymphoma revealed by platelet satellitism and lympho-agglutination phenomenon around atypical lymphocytes. Microcystin accumulation in freshwater bivalves from Lake Taihu, China, and the potential risk to human consumption. Despite the high information value of MHC, it is still not used in zoological studies as often as it deserves. Simple and inexpensive email-based encouragements to do daily stair-walks together with colleagues at work improves cardiovascular health among adults in sedentary occupations. However, no study has compared the utility of these two modalities. The body temperatures of 183 newborn babies which were well cared for by their mothers was 33.0 to 37.7 degrees C about 10 hr after birth. Occurrence of organic contaminants in sewage sludges from eleven wastewater treatment plants, China.

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To be accepted into telephone counselling programme, potential participants had to be able to be contacted by phone regularly. Part II: Clinical and Radiographic Results as Evaluated Utilizing the Vertebral Endplate Yue-Bertagnoli (VEYBR) Classification. A five-year study of particulate matter (PM2.5) and cerebrovascular diseases. Usually one finds that dissipation tends to make a quantum system more classical in nature. Both concatenated and consensus tree phylogenies did not support MPEC monophyly or the monophyly of either transient or persistent phenotypes. Aberration evaluation of alignment optics in lithographic tools by use of a step-height structure highly sensitive to the asymmetry of an optical image. Development and validation of a custom microarray for global transcriptome profiling of the fungus Aspergillus nidulans.

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High-dose hydromorphone (Dilaudid) for coronary artery bypass surgery. The effect of alcohol on life- and health-threatening punishable offenses and their prevention. Experimental remarks on the utilization of biological tissue adhesives in lymphovenous anastomosis. Its presence was not constantly associated with morphological lesions of the liver. Pseudo-electrokinetic packing of high efficiency columns for capillary electrochromatography. To gain some understanding of the attitudes and behaviours of Indigenous young people in Townsville concerning relationships, contraception and safe sex.

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Feulgen-DNA values -nuclear surface and average absorption ratio- surface covered by condensed chromatin correlations support these assumptions. The afferent filament arteriole drained toward the efferent filament arteriole, forming the loop at the posterior extremity of the gill filament. Today, the most commonly used repair is undersized annuloplasty. This paper reports the findings of a pilot study in which a radioisotope technique was used in the detection of cervical metastases in patients precose drug with histologically proven oral squamous cell carcinomata. It is as efficacious as IV morphine in providing effective analgesia during laparoscopic cholecystectomy. The procedure is an application of a statistical method known as the Expectation Maximization algorithm.

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The test solution was gavaged before ip glucose injection in normal rats or gavaged together with glucose in GK rats. Wistar rats were randomly divided into 3 periods (2, 7 and 15 days) and assigned to 4 groups (control, sham, inflammation, and immobilization). Occurrence of the transition of apical architecture and expression patterns of related genes during conversion of apical meristem identity in G2 pea. Urinary tract (UT) cytology has been used successfully to diagnose high-grade urothelial carcinoma but is reported to have poor sensitivity for low-grade urothelial neoplasms (LGUNs). It has been demonstrated that lithium (Li) and valproate (VPT), first line mood stabilizers, increase BDNF content in rat hippocampus and frontal cortex, which suggests that the regulation of neurotrophic factors might be associated with their pharmacological effects. We find no gender differences in bereavement effects on depressive symptoms in either short or long term, net of widowhood duration.

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