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Amifru (Spironolactone)

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Amifru is used to treat fluid retention (oedema) caused by liver disease, kidney problems or heart failure. Oedema occurs when fluid leaks out of your blood vessels, causing swelling in the tissues of your lungs, feet or ankles. This makes you feel breathless or your legs feel puffy

Other names for this medication:
Aldostix, Amifru, Aquamide, Dyamide, Dytor, Fruselac, Frusis, Lactone, Lasilactone, Metolactone, Spilactone, Spiromide, Spironolactone, Spirotic, Torlactone, Tormax, Torsid, Zator

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Yasmin, Arimidex, Aricept, Levaquin, Mobic, Imuran, Protonix, Alprostadil

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Also known as: Spironolactone


Generic Amifru is a perfect remedy, which helps to fight with hyperaldosteronism, hypokalemia, edema, ascites, hirsutism, alopecia (baldness), acne. It can also be used together with other medicines to treat myasthenia gravis, precocious puberty, high blood pressure. Generic Amifru acts by controlling the level of water and salt and by decreasing the potassium loss from your body. Amifru is also known as Spironolactone, Spirotone, Spiractin, Osyrol, Spiroctan, Spirolon, Verospiron. It is aldosterone receptor antagonists. Generic name of Generic Amifru is Spironolactone. Brand names of Generic Amifru are Amifru, Spiractin, Spirotone, Spironol, Berlactone, Novo-Spiroton.


Usual Adult Dose of Amifru for Edema:

25 to 200 mg orally per day in single or divided doses

Usual Adult Dose of Amifru for Hypertension:

Initial dose: 50 to 100 mg orally per day in single or divided doses

Usual Adult Dose for Congestive Heart Failure:

Initial dose: 25 mg orally once a day assuming serum potassium is less than or equal to 5 mEq/L and serum creatinine is less than or equal to 2.5 mg/dL

Usual Adult Dose for Primary Hyperaldosteronism:

Diagnostic dose:

Usual Adult Dose for Hypokalemia:

25 to 100 mg orally per day

Detailed Amifru dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store below 25 degrees C (77 degrees F). Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amifru are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Amifru if you are allergic to Generic Amifru components. Do not take Generic Amifru if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Amifru can harm your baby. Do not take Generic Amifru if you are taking potassium-sparing diuretics (such as Aldactazide, amiloride (Moduretic, Midamor)), triamterene (such as Maxzide, Dyazide, Dyrenium)). Be careful using Generic Amifru if you take inhibitors (enalapril (such as Vasotec), fosinopril (such as Monopril), captopril (such as Capoten), benazepril (such as Lotensin), lisinopril (such as Zestril, Prinivil), quinapril (such as Accupril), moexipril (such as Univasc), ramipril (such as Altace), trandolapril (such as Mavik)); oral steroids (dexamethasone (such as Decadron, Dexone), prednisone (such as Deltasone), methylprednisolone (such as Medrol)); aspirin and other nonsteroidal anti-inflammatory medicines (naproxen (such as Aleve, Naprosyn), ibuprofen (such as Advil, Motrin), indomethacin (such as Indocin)); diuretics; barbiturates, phenobarbital; digoxin (such as Digitek, Lanoxicaps, Lanoxin)); high blood pressure medicines, lithium (such as Lithobid, Eskalith); perindopril (such as Aceon).It can be dangerous to use Amifru if you suffer from or have a history of liver disease, kidney disease, potassium high levels in your blood, problems with urination. Be careful with this drug if you are going to have a surgery. Avoid food with high level of salt. Avoid dehydration. Avoid medicines which cause lightheadedness. You should be careful when you are driving or operating machinery. Do not stop taking Generic Amifru suddenly.

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Novel Technique for Subretinal Injection Using Local Removal of the Internal Limiting Membrane. Several features of the eye make it an excellent candidate for cell-based therapy to treat corneal and retinal degenerative disease. A detailed analysis of the calcific crystals revealed hydroxyapatite and octacalcium phosphate. Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse. Sex chromosomal aneuploidy is the most common disorder of sex chromosomes in humans, with an incidence of 1 in 400 newborns. In typical clinical practice, adalimumab was effective and well-tolerated in patients with RA previously treated with etanercept and/or infliximab. A clinical registry of dementia based on the principle of epidemiological surveillance.

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Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analysis of C-12 hydroxylase EryK from Saccharopolyspora erythraea. History and overview of comprehensive interdisciplinary breast centers. The lipophilic yeast Pityrosporum orbiculare has been cultured quantitatively, in 10 volunteers, from clinically normal skin on the chest, back, upper arm, lower leg, and dorsal aspect of the hand. To determine the association between opioid use and lower extremity fracture risk in men with spinal cord injury (SCI). The number of physicians per 10,000 population is a basic health indicator used to determine access to health care. Prognostic Significance of VEGF after Twenty-Year Follow-up in a Randomized Trial of Fenretinide in Non-Muscle-Invasive Bladder Cancer.

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The full dose of hormone should not be given before the termination of bone growth. A new mutual molecular dataset diversity index (MMDDI), individual molecular dataset diversity index (IMDDI), and volume ratio (VR) are proposed to assess molecular dataset diversity. The proto-oncogene c-myc has a central role in multiple processes important for embryonic development, including cell proliferation, growth, apoptosis, and differentiation. Our results show that serum levels of malondialdehyde and nitric oxide increased significantly during acute infarction, coming back to normal levels 30 days after infarction, which suggest that both substances are potential tools to predict cardiac function recovery. The GA analogues displayed negative correlations with mRNA expression levels of the multidrug resistance protein 1 (MRP1, ABCC1).

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In this retrospective cross sectional study, 26 patients with PV were enrolled from January 2010 to December 2014. We found robust evidence supporting insertion of a silver alloy-coated catheter to reduce the risk of CAUTIs for up to 2 weeks in adult patients managed by short-term indwelling catheterization. Chemical shift perturbation is used to elucidate contacts made between the N-terminal domain and the C-terminal domain. Baccalaureate nursing students experience anxiety before working with patients with mental illness who hear voices. Mould filling of Ag-Pd-Cu-Au and Ag-Zn-Sn-In alloy castings made using a rapidly prepared gypsum-bonded investment material. All first 178 consecutive patients who underwent resection of a rectal tumor using TEM in our institution from April 2011 to September 2013 were included. Sacrococcygeal teratoma in adults usually has no typical clinical symptom and signs and is often misdiagnosed. Experimental partial ureteric obstruction: pathophysiological changes in upper tract pressures and renal blood flow. No unusual surgical complications occurred, and the most dreaded complication of dural penetration by drilling or screw placement was not observed.

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Quantitative localization of neurons projecting to the mouse main olfactory bulb. The entorhinal cortex mainly modulates the hippocampal activity via direct axonal projections. However if this study shows a more effective adaptive response by the fetal organism, it also calls for further studies to determine the limit of this response that definitely changes the fate of a fetus under these conditions of cellular stress. SHORT-TERM EFFICACY OF LOW-LEVEL LASER THERAPY IN PATIENTS WITH KNEE OSTEOARTHRITIS: A RANDOMIZED PLACEBO-CONTROLLED, DOUBLE-BLIND CLINICAL TRIAL. On the comprehensibility of German hospital quality reports: systematic evaluation and need for action.

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Molecular bacteria-fungi interactions: effects on environment, food, and medicine. The effect of dietary zinc on the sodium and potassium levels in plasma, soft and peripheral tissues, bone and hair were determined. Spontaneous intracerebral haematomas: surgical versus conservative treatment based on Glascow Coma Scale score and computer tomography data. Numerous studies indicates that the complex network of interactions between the host organism and its microbiome can have a very significant impact on the health condition of the host. Similarly, instrumentation-induced variability sources of system stability and system-dependent response were also analyzed on skin and a nonvolatile biological tissue analog. Epstein-Barr virus-encoded RNA in situ hybridization was positive. Studies evaluating the association between chronic pain and methadone maintenance treatment response were eligible for inclusion in this review. Partitioning of fresh crude oil between floating, dispersed and sediment phases: Effect of exposure order to dispersant and granular materials. Short-term efficacy of back injury intervention project for patient care providers at one hospital. ASSOCIATION BETWEEN DENTAL AND SKELETAL MATURATION STAGES IN CROATIAN SUBJECTS.

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Copper poisoning developed in 1 adult and 3 juvenile llamas after excessive dietary intake of copper resulted in an incorrect copper:molybdenum ratio. The results showed that administration of 500 - 2,000 mg/kg of Mecasin did not cause any changes in weight or in the results of necropsy examinations. We found that the rate of inositol phospholipid hydrolysis was proportional to the number of binding sites specific for 3H-substance P, suggesting that binding sites revealed by 3H-substance P autoradiography correspond to functional substance P receptors. In the present study, 24-h saline cultures of the amebocyte-producing organ (APO) of the schistosome-transmitting snail Biomphalaria glabrata were used to test for the potential involvement of protein kinase C (PKC) signalling in hematopoiesis. Plasma AFP levels were significantly higher in one subject with IUGR than in other patients. Caution should be exercised in extrapolating renal disease changes in active renal secretion to changes in passive renal elimination and the reverse. There have been many studies in India on etiology and prevalence on regional basis. The frequency of KUTD in this population is compared to available rates from other sources. A standard PiCCO2 was modified with software allowing its transformation into a simulator.

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These findings indicate that LORR is associated with enhanced GABAergic neurotransmission, but that immobility in response to noxious stimulation is not, suggesting that LORR and immobility are mediated through different neuronal pathways and/or regions in the central nervous system. Given that WP had comparable acute intestinal toxicities to those associated with SF, WP IMRT appears to be a feasible approach for the treatment of prostate cancer despite dosimetric disadvantages. Factors that can complicate glycemic control include the severity of illness, medications, and inconsistent dietary intake. Phylogenetic diversity and distribution of dissimilatory sulfite reductase genes from deep-sea sediment cores. The data analysis was performed on values of DeltaDeltaG(double dagger)K(d) which reflect the strength of short range interactions, while DeltaDeltaG(o)K(D) values which include the effects of long range electrostatic forces that alter specifically DeltaDeltaG(double dagger)k( can you drink alcohol on lamisil a) were treated separately.

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Extended right hemicolectomy and left hemicolectomy for colorectal cancers between the distal transverse and proximal descending colon. The apparent partial growth hormone insensitivity in this group of idiopathic short-stature subjects is not related to heterozygous, dominant-negative variants of the intracellular signalling domain of the GHR. Pretreatment with the 5-HT(2C) receptor antagonist mesulergine (1 stemi plavix dose and 10 microg) and the 5-HT(3) receptor antagonist tropisetron (1 and 10 microg) reversed totally the antinociception induced by 5-HT. Mauritius lies in the southwest Indian Ocean about 1250 miles from the African coast and 500 miles from Madagascar. A model of ischemic stroke in the rat was established after transient middle cerebral artery occlusion (MCAO) followed by reperfusion. The data reviewed are discussed with the aim of underlining unmet needs and making recommendations for future studies on omalizumab use.

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Contrary to their claims, genetic relatedness is important and causal, workers are agents that can evolve to be in conflict with the queen, and eusociality is not so difficult to evolve. Examine the effect of electrical stimulation of nucleus tractus solitaries (NTS) on cardiac-somatic motor reflex (CMR) that induced by intrapericardial administration of capsaicin to clarify the spinal cord mechanism of NTS involved in cardiac nociception in rat. The article presents the comparative analysis of techniques of evaluation of costs of hospital treatment using medical economic standards of medical care and clinical statistical groups. The purpose of this study was to evaluate sonographic features for distinguishing clinically atypical subacute thyroiditis from malignant thyroid nodules. Decayed internal ORF sequences indicated that they were non-autonomous elements. The analysis was carried out using gas chromatography equipped with flame ionization detection. Intrauterine fetal therapy of NIHF with massive pleural effusion - a case study. Osteoblast differentiation of valve interstitial cells (VICs) is a key step in valve calcification, but the molecular mechanisms involved are not fully understood. The binding causes the changes in the electrode response of labeled sugar.

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Can concepts of neurodevelopment and neuroplasticity explain post-traumatic psychoses?. Microvascular caliber changes in intramucosal and submucosally invasive esophageal cancer. Titanium dioxide nanoparticles (TiO2 NPs) are extensively used in consumer products. Crack cocaine use and unprotected anal sex are important risk criteria to identify high-risk women for HIV-efficacy trials. Methodological approaches to the assessment of alimentary load of nutritional supplements (ALNS) have been based. Femoral artery thrombosis following percutaneous treatment with thrombin injection of a femoral artery pseudoaneurysm: a case report. Contemporary cognitive-behavior therapy underscores the importance of the culture-specific variables in the treatment of psychological problems. Hepatitis B virus (HBV) DNA was found to be integrated into seven sites in the DNA of the PLC/PRF/5 hepatoma cell line as determined by digestion with the restriction endonuclease HindIII which does not cut through the viral genome.

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