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Amitin (Amitriptyline)

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Amitin is a type of drug called a tricyclic antidepressant. These drugs were originally developed to treat anxiety and depression, but when taken at a low dose they can reduce or stop pain. Amitin works by increasing the amount of serotonin your brain makes.

Other names for this medication:
Amiclozor, Amicon, Amicure, Amidez, Amiline, Amimax, Amitar, Amitone, Amitop, Amitrim, Amitriptyline, Amitrol, Amitryn, Amitryptyline, Amitwix, Amiwel, Amixide, Amize, Amoten, Amsha, Amtipax, Amypres, Anitryp, Aptric, Arpidox, Crypton, Endep, Goldep, Kamitrin, Latiln, Libral, Librodep, Limbitrol, Nextrip, Relidep, Ronet, Sereval, Tadamit, Tridep, Tryptomec, Vanatrip, Zodep

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Also known as: Amitriptyline


Amitin target is the treatment of depression. Amitin is acting by increasing the amounts of certain natural substances in the brain that are needed to maintain mental balance. It is tricyclic antidepressant. Generic name of Amitin is Amitriptyline. Amitin is also known as Amitriptyline, Amitryptyline, Amidon, Amitryn, Tryptanol, Endep, Elatrol, Tryptizol, Trepiline, Laroxyl, Saroten, Triptyl, Amitrip. Brand names of Amitin are Amitin, Endep, Vanatrip.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitin dosage information


If you overdose Amitin and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitin overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Amitin if you are allergic to amitriptyline, or:

if you have recently had a heart attack.

Do not use Amitin if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

Tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram, escitalopram, fluoxetine (Prozac), fluvoxamine, paroxetine, sertraline (Zoloft), trazodone, or vilazodone.

To make sure Amitin is safe for you, tell your doctor if you have ever had:

bipolar disorder (manic-depression) or schizophrenia; mental illness or psychosis; liver disease; heart disease; a heart attack, stroke, or seizures; diabetes (amitriptyline may raise or lower blood sugar); glaucoma; or problems with urination.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor should check your progress at regular visits. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Tell your doctor if you are pregnant or breastfeeding.

Amitin is not approved for use by anyone younger than 12 years old.

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There is a lack of studies that assess whether the DSM-IV criteria for Major Depressive Episode (MDE) that use a diagnostic threshold are valid for the elderly and whether each symptom of depression contributes equally to impairment in this group. Reversal is associated with lower IOP, but is not associated with improved visual function. Dietary patterns, food groups, and nutrients as predictors of plasma choline and betaine in middle-aged and elderly men and women. There was no correlation between AI, left, or right 2D:4D, BPRS, or SAPS in the schizophrenia group. Callus formation and toe deformity were identified as relevant clinical predictors for all forefoot regions. Selective determination of doxorubicin and doxorubicinol in rat plasma by HPLC with photosensitization reaction followed by chemiluminescence detection. Rationale and design of the Karolinska-Rennes (KaRen) prospective study of dyssynchrony in heart failure with preserved ejection fraction.

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The federal health reform agenda supports changes that will eventually permit behavioral health to be fully integrated and will allow the health of the population to be the primary target of intervention. Bilateral persistent trigeminal arteries associated with bilateral carotid aneurysms. The changes in PaCO2 were directly proportional and the changes in pH contrarily proportional to the temperature of the insufflated CO2. The rupture of a cerebral aneurysm can result in a hemorrhagic stroke. Children with special health care needs who use EMS are more likely to receive advanced life support service, to receive prehospital procedures, and to be transferred from one health care facility to another. CC-MS shows that extracts with high inhibitory activities contain many fatty acids such as linoleic acid, linolenic acid, and palmitic acid, etc. Molecular characterization of Nipah virus from Pteropus hypomelanus in Southern Thailand. The symmetric cost function includes mutual information (MI) as a similarity measure, regularization of the transformation, and inverse consistent constraint (ICC).

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