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Aniclindan (Clindamycin)
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Aniclindan

Aniclindan is used for treating serious infections caused by certain bacteria. Aniclindan is a lincomycin antibiotic. Aniclindan kills sensitive bacteria by stopping the production of essential proteins needed by the bacteria to survive.

Other names for this medication:
Albiotin, Arfarel, Bexon, Bioclindax, Borophen, Cleorobe, Clidets, Clinacnyl, Clinbercin, Clindal, Clindalind, Clindamax, Clindana, Clindasol, Clindastad, Clindesse, Clindoral, Clinex, Clinfol, Clinika, Clinium, Clintabs, Clinwas, Daclin, Dalacine, Damiciclin, Indanox, Klamoxyl, Klimicin, Klindacin, Klindamicin, Klitopsin, Lindacil, Lindacyn, Milorin, Opiclam, Sobelin, Torgyn, Trexen, Veldom, Ygielle, Zindaclin, Zindacline, Zumatic

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Also known as: Clindamycin

Description

Clindamycin belongs to the family of medicines called antibiotics. Topical clindamycin is used to help control acne. It may be used alone or with one or more other medicines that are used on the skin or taken by mouth for acne. Topical clindamycin may also be used for other problems as determined by your doctor.

Clindamycin is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain clindamycin. It may not be specific to Aniclindan HCl. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Take the capsule with a full glass (8 ounces) of water. This is to prevent irritation of the esophagus (tube between the throat and stomach).

Measure the oral liquid correctly using the marked measuring spoon that comes with the package. The average household teaspoon may not hold the right amount of liquid.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you have a "strep'' infection, you should keep using this medicine for at least 10 days. This is especially important in "strep" infections. Serious heart problems could develop later if your infection is not cleared up completely. Also, if you stop taking this medicine too soon, your symptoms may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take each dose at evenly spaced times day and night. If you need help in planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules and solution): For treatment of bacterial infections: Adults—150 to 300 milligrams (mg) every 6 hours. For more severe infections, 300 to 450 mg every 6 hours. Children weighing 10 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 16 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 or 4 equal doses. For more severe infections, the dose is usually 16 to 25 mg per kg of body weight per day, divided into 3 or 4 equal doses. Children weighing 10 kg or less—Dose is based on body weight and must be determined by your doctor. The dose is usually 37.5 milligrams (mg) or 1/2 teaspoonful 3 times a day.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms include bloody or watery diarrhea, which may result if you absorb Aniclindan T through your skin by applying too much.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Aniclindan HCl dosage information

Side effects

The most common side effects associated with Aniclindan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of vaginal clindamycin in the elderly with use in other age groups.

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This is accomplished without requiring typical feature-feature, feature instance, or instance-instance co-occurrence data. These results show for the first time that this new reporter assay, based on the VEGF-VEGFR-NFAT pathway, can be a viable supplement to the HUVEC assay and employed in potency determination of BVZ and other kinds of anti-VEGF antibody-based biotherapeutics. A foreign body granuloma is a non-allergic chronic inflammatory reaction that is mainly composed of multinucleated giant cells. Eleven cases were original articles, 7 reviews, 6 case reports, 3 editorials, 3 special articles and 3 letters to the editor. Prevalence of deficiency and dietary intake of iron, zinc and copper in Chilean childbearing age women. Patterns of monoclonal cross-reactivity against California serogroup viruses are compared with the currently accepted antigenic relationships. A national survey examining obstetrician perspectives on use of 17-alpha hydroxyprogesterone caproate post-US FDA approval. E2F1 participates in the regulation of the transcriptional activation of KIR3DL1 gene. The present animal experiments revealed that repeated intra-articular administration of alpha 2-macroglobulin . The ERAN resembles both the physical MMN and the abstract feature MMN in a number of properties, but the cognitive mechanisms underlying ERAN and MMN partly differ: Whereas the generation of the MMN is based on representations of regularities of intersound relationships that are extracted online from the acoustic environment, the generation of the ERAN relies on representations of music-syntactic regularities that already exist in a long-term memory format.

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Characteristics of pollutant gas releases from swine, dairy, beef, and layer manure, and municipal wastewater. Urinary extravasation was evident in the three undiverted technique animals. Culprit for low aerobic fitness in down syndrome: is deconditioning guilty as charged?. MAEL HMG-box failed to bind double-stranded (ds)DNA but bound to structured RNA. Tissue factor (TF) is a 47 kDa membrane protein that initiates coagulation by binding to FVII(a) and FX(a) and is a risk factor for thrombosis in many disease states.

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The herds using carbadox (40 to 50 ppm) had a lower prevalence of Brachyspira species than those using olaquindox (40 to 50 ppm). Its role in the reproductive tissue is to stabilize seed set and productivity. These novel findings could have implications for developing policy guidelines for statin therapy in forestalling vascular complications in young T1DM. Modelers lack a tool to systematically and clearly present complex model results, including those from sensitivity analyses. SCD5-induced oleic acid production reduces melanoma malignancy by intracellular retention of SPARC and cathepsin B.

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Further investigation of the possible causative mechanism for these lesions--drug solution pH, osmolality, or impurities--suggests that impurities in the solution are the most likely cause. However, ES acted as an endocrine disrupting chemical in this species as the morphometry of gonadotropin-releasing hormones (GnRH) producing cells was altered. Effect of glycine pretreatment on the shear bond strength of a CAD/CAM resin nano ceramic material to dentin. We suggest repeated TURBT is to be recommended in patients with high grade, T1 stage or multi-focality non-muscle-invasive bladder cancer. Salivary proteins in plaque do not parallel their relative concentration in saliva. Playing standard influenced the pattern of load/min (AU) accumulation across a match, and individual vector analysis suggests that different-standard players have dissimilar movement characteristics. Quantitative cytologic and histologic changes in the middle ear after the injection of nontypable Hemophilus influenzae endotoxin. The field patterns over the scalp at the peak latencies indicated a single current dipole as an equivalent field generator.

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Understanding the interaction between energetic ions and freestanding graphene towards practical 2D perforation. Compared with traditional method of correlation coefficient analysis, the quantitative indicators based on nervous energy distribution characteristics are more effective in reflecting the dynamic features of the neural network activities. Synthesis of a superoxide dismutase derivative that circulates bound to albumin and accumulates in tissues whose pH is decreased. The amino acid sequences of these proteins do not display any apparent homologies to the DNA binding domains of prokaryotic transcription regulators and a DNA binding motif for any one of the MarR homologues is currently unknown. Soft denture lining-materials are more susceptible to microbial adhesion than hard denture base acrylic resin. Functionally the primate and human ACC are believed to be involved in the monitoring of actions and outcomes to guide decisions especially in challenging situations where cognitive conflict and errors arise. The distribution in Turkey including previous records and the material examined were shown on a map, and the distribution in Palearctic Region was given. Testicular cancer in androgen insensitivity syndrome in a Mexican population. Regarding the latter, this study does therefore not yield evidence for a particular efficacy of TPM in RSE. Identifying match statistics that strongly contribute to winning in football matches is a very important step towards a more predictive and prescriptive performance analysis.

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We performed a longitudinal study of patients with a first-ever large vessels stroke and resulted positive at H. An animal model demonstration of enhanced clearance of nontypable Haemophilus influenzae from the respiratory tract after antigen stimulation of gut-associated lymphoid tissue. Following pre-operative assessment, patients were individually randomised to intervention or control by a computer-generated block randomisation algorithm stratified by age and centre. However, public understanding of the role of evidence-based care may be different. A novel but rare keratin-8 Arg341-to-Cys is identified in IBD patients. A new member of the TNF-ligand superfamily member, osteoclast differentiation factor (ODF/OPGL/RANKL/TRANCE), was recently identified. Oxidative stress is generated in plants because of inequalities in the rate of reactive oxygen species (ROS) generation and scavenging.

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Altogether, we reveal transcriptional targets of two key pluripotency-related genes in ES cells--Stat3 and c-Myc, thus providing further insight into the ES cell transcriptional network. Pancreatic cancer has been on the sharp increase in Japan in recent years, the rate of increase being as high as for lung and liver cancers. Dermoscopy has superior specificity and sensitivity to naked-eye examination according to a meta-analysis of nine level-2 studies. Individual mutation of three solvent-exposed lysines in the villin headpiece subdomain significantly stabilizes the protein, but the mechanism of stabilization is very different in each case. Two stochastic simulation models (InterSpreadPlus (ISP) and the modified Davis Animal Disease Simulation model (DTU-DADS)) were used to simulate the spread of FMD in Denmark using different control strategies. Compulsive checking is one of the most common symptoms of obsessive-compulsive disorder (OCD). A systematic review of the literature was carried out to determine the evidence for the reliability and validity of the assessment methods used in veterinary medical education.

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With regard to the mainstreaming of students with Down syndrome, the 2003 legislation has consolidated the situation. Unfairness is an independent predictor of increased coronary events and impaired health functioning. All patients underwent thyroidectomy and their FDG-PET, and MIBI thyroid scan results were compared with post-thyroidectomy pathology results. Poly(lactide-co-glycolide acid)/biphasic calcium phosphate composite coating on a porous scaffold to deliver simvastatin for bone tissue engineering. Heart rate variability (HRV) reflects cardiac autonomic regulation and has been used to evaluate dysfunction of the autonomic nervous system in hypertension and cardiovascular diseases.

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The cellular composition of the involved vascular wall was studied by the method of alcohol-alkaline dissociation. An effective biologic agent in bladder cancer gene therapy, intravesical treatment with rAAV-ES inhibits the angiogenesis, thus inhibiting the tumor formation and progression. Major progress has been made in elucidating the calcium release mechanism involved in excitation-contraction coupling. Friction and relative energy dissipation in sheared granular materials. The HK-2 cell line, transfected with MT-3, may be an effective model to study the process of MET. Here we show that active sliding between cytoplasmic microtubules can occur in microtubule bundles of the amoeba Reticulomyxa.

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In addition to their homomolecular coupling capabilities, laccases are also able to couple a hydroxylated aromatic substrate with a nonlaccase substrate of variable structure to create new heteromolecular hybrid molecules. Among them, 10 paired HGPIN and PCa were prepared to perform miRNA microarray and quantitative real-time PCR. The Sequence and Structure Determine the Function of Mature Human miRNAs. The plasmid DNA experiments demonstrated that idarubicin could undergo bioreduction by P450 reductase with the resulting formation of DNA strand breaks. Radiological Investigations in Vertical Banded Gastroplasty Patients. A thorough understanding of glycopeptide immunity in this producing microorganism may be particularly relevant to predict and eventually control the evolution of resistance that might arise following introduction of dalbavancin and other second generation glycopeptides into clinics. P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines. The reaction was more potently inhibited by lactose than by beta-methyl-galactose. These results suggest that cellular stress induces the elevation of both PrP mRNA and protein synthesis.

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Within the CNS the different subtypes are found in neurons, both pre- and/or postsynaptically, where they mediate modulatory roles and in glial cells. Type 1-polarized effector DC are resistant to further modulation, which may facilitate their potential use in immunotherapy. Each group was divided into subgroups of cocaine-abused and non-cocaine-abused rats. Effect of angiotensin converting enzyme inhibitor and angiotensin II type 1 receptor antagonist on metabolism and contraction in ischemia-reperfused rabbit heart. Key methodologies for safe implementation and credentialing of spine radiosurgery have been identified. However, further studies examining these and other psychometric properties need to be conducted in other countries. RNA viruses have a great potential for genetic variation, rapid evolution and adaptation. A case series of patients with AO/ASIF 41-C type fractures treated with the less invasive stabilization system for the proximal lateral tibia (LISS PLT) were prospectively followed up until 11-13 months after surgery. Although these differences are partly due to the degree of westernization, genetic factors also contribute.

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The eyelid pressure was also measured in 34 normal eyes of 19 non-CL wearers who were not part of Study 1. Acrosome exocytosis is a synchronized and tightly regulated all-or-nothing process, with no recycling of membranes. Randomized clinical trials (RCTs) remain the foundation for assessing and introducing evidence-based therapies into cardiovascular (CV) medicine. Literature review revealed the rarity of uneventful recovery as has been seen in our case. These interactions can affect not only to gastrointestinal tract but can be related to different processes and organs. Plasma concentrations of growth hormone and somatomedin C in dwarf and normal chickens. Increased insulin resistance has been associated with serious pregnancy complications, such as gestational diabetes mellitus (GDM) and pre-eclampsia. Presentation with gastrointestinal symptoms and high case fatality associated with group W meningococcal disease (MenW) in teenagers, England, July 2015 to January 2016. Primary and secondary headache disorders have established diagnostic criteria in the International Classification of Headache Disorders IIIb, as well as classic findings, which although not part of the formal criteria are often suggestive of a particular diagnosis. Ischemic heart disease risk factors in middle-aged Seventh-day Adventist men and their neighbors.

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The DA receptor antagonists used in this study did not influence locomotion. Hypertension is a common outcome associated with obstructive sleep apnea (OSA), a prevalent yet poorly treated cardiovascular disease. Intriguingly, H4ac and H3K27me3 were detected in sperm tail fractions via western blot analysis. High-sensitivity C-reactive protein (hsCRP) is a cardiovascular risk marker. For molecular US imaging, MB are functionalized with antibodies or peptides, in order to visualize receptor expression by angiogenic or inflamed endothelium. Sequential surgery could be advantageous to BCVA outcomes by minimizing postoperative VH, which is significantly more frequent after combined surgery. Ccl2, Gfap, and Mmp 9 mRNA levels, and MMP-2 and -9 enzymatic activities were increased after TBI regardless of brain DHA level. These results resemble those previously reported for the human basophil. Postoperative pain levels seem to be primarily influenced by the performed reconstruction. Investigation of structure-activity relationships of Oxyntomodulin (Oxm) using Oxm analogs.

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A meta-analysis of clinical trials assessing the effect of radiofrequency ablation for breast phenergan scheduled drug cancer. Although omalizumab is generally well tolerated, reports on potential anaphylactic reactions as well as an association with Churg-Strauss syndrome necessitate close monitoring. The use of a customized radiation shield that combines tissue-equivalent bolus material with protective material addresses these issues. This occurs with similar excitatory synaptic drive throughout postnatal maturation, but with a greater prevalence at younger ages. Histologic findings in endoscopic biopsies from the stomach, duodenum, ileum, and colon were unremarkable and protozoal organisms were not observed.

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Thirty-three patients who had undergone transpedicular biopsy for vertebral body lesions were retrospectively evaluated. MEF2 transcription factors (TFs) play essential roles in this process but how these broadly expressed factors contribute to the generation of specific cell types during development is poorly understood. After UV excitation of an aromatic chromophore of a protonated peptide, a CO(2) laser further excites the molecules, increasing their vibrational energy and hence their dissociation rate, allowing detection of the UV excitation by monitoring the resulting photofragments. We demonstrate here the downregulation of Rest/Nrsf expression in a mouse neuroblastoma cell line. Four groups of subjects were recruited from several sources: 1) bipolar proband-parent trios or sib-pair-parent nuclear families, 2) unrelated bipolar participants who had completed the BALM morningness-eveningness questionnaire, 3) sib pairs from the GenRed Project having at least one sib with early-onset recurrent unipolar depression, and 4) a sleep clinic patient group who frequently suffered from depression. Fetal alveolar type II (AT2) cell proliferation was increased with rhVEGF treatment only with mesenchymal cell (MC) coculture, and these effects were attenuated with anti-HGF antibody treatment. The use of the Walkman mini-stereo system in the management of tinnitus. Hygienic and clinical study of elective and acute hip operations. It is a very aggressive malignancy with a median survival of less than 1 year from diagnosis. The hypothesis was that after surgical excision of posttraumatic heterotopic ossifications at the proximal hamstrings with concomitant repair of the tendons to the ischium, significant functional improvement with low risk of postoperative complications can be expected at minimum 2-year follow-up.

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The present post-hoc analysis showed that compared to amlodipine benidipine results in a greater reduction in albuminuria accompanied by an improved composite ranking of relative risk according to the KDIGO CKD severity classification. Guanine derivatives modulate extracellular matrix proteins organization and improve neuron-astrocyte co-culture. This article reviews the current state of (19)F-based cell tracking and lung imaging using magnetic resonance imaging and describes the link between the methods across these fields and how they may mutually benefit from solutions to mutual problems encountered when imaging (19)F-containing compounds, as well as hardware and software advancements. Plasticizers in the manufacture of novel skin-bioadhesive patches. High fat percent in Indian adults may have its origins at birth (Fetal origin hypothesis). Events that offset the balance of the UPR branches can have devastating consequences, and UPR misregulation has been correlated with various diseases, including metabolic and neurodegenerative diseases and cancer. Preventing central venous catheter-associated bloodstream infections: development of an antiseptic barrier cap for needleless connectors.

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This subpopulation of pregnant women was generally estimated not to be in high-risk for toxicity induced by OTA. Use of genetic tests among neurologists and psychiatrists: knowledge, attitudes, behaviors, and needs for training. On the mechanism of B(C6F5)3-catalyzed direct hydrogenation of imines: inherent and thermally induced frustration. Compared with the sighted, the early blind subjects showed decreased functional connectivity between the left PVA and the bilateral supplementary motor area (SMA), pre- and postcentral gyri, superior parietal lobule, and the left superior and middle temporal gyri. In our study, we examined the relationship between demographic data, the severity of symptoms, self-stigma, and QoL in patients with schizophrenia spectrum disorder.

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These topological alterations might be a surrogate marker of human focal epilepsy and disclose some changes over time. The prognostic significance of S-phase analysis in stage Ta/T1 bladder cancer. The role of the left ear/right hemisphere as a facilitator of processing for linguistic and nonlinguistic material was suggested by the results of this study. or Alternaria sp.) were identified only by culture-independent methods. Applying this method to estimate pH with the interactive properties of computer-based ordering systems could enhance calcium and phosphorus administration to very low birth weight infants.

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The discriminant features will be not consistent when the same but shifted signal is applied. Merkel cell-poor trichoblastoma with basal cell carcinoma-like foci. Elective tracheostomy is an alternative treatment in patients with severe obstructive sleep apnoea syndrome and CPAP failure. This study examined neuronal activity in the prefrontal cortex (PF) involved in the process of motor selection in accordance with two behavioral rules. Differential activation of cytokine genes in normal CD4-bearing T cells is stimulus dependent.

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If the patient desires to try to carry the fetus to viability after counseling on the possible associated risks of malignancy, it is possible to achieve fetal viability if (1) there is decline in the serum hCG level after it peaks before the second trimester, (2) ultrasound reveals degeneration of the molar part, and (3) there are no complications of pregnancy. The aim of this study was to identify whether arsenic (As) exposure could induce hippocampal neural apoptosis in vivo. Development and validation of new analytical method for acrolein in air. Clinical study on constitutional herbal tea for treating chronic fatigue. Differently from other studies, we find that the object contour alone also improves memory color.

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The utilizable protein content of the wheat products was higher than that of the corn products, while the gross energy content was similar for both. In cells, ubiquitination of endogenous ataxin-3 increases when the proteasome is inhibited, when excess Ub is present, or when the unfolded protein response is induced, suggesting that the cellular functions of ataxin-3 in protein quality control are modulated through ubiquitination. We examined correlates of serum TMAO and the relations among serum TMAO concentrations, all-cause mortality, and cardiovascular mortality and hospitalizations in a nationally derived cohort of patients new to hemodialysis (HD). The most ubiquitous and widespread modification to fatty acids, which results tenormin 50 mg side effects in a great diversity of different structures, is the insertion of double bonds. The emergence of antiretroviral-resistant viruses is one of the most important factors affecting the prognosis of HIV-1 infected patients today. Effect of a comprehensive programme to provide universal access to care for sputum-smear-positive multidrug-resistant tuberculosis in China: a before-and-after study. An e-questionnaire was distributed during our HNC awareness campaign at the Red Sea Mall in Jeddah. TNF and IL-1 increase matrix metalloproteinase-3 (MMP-3) expression in the trabecular meshwork (TM).

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Novel strategies must be developed to completely restore heart function in DMD. While control larvae molt a second time, these larvae fail to do so and die after few days of straying. Total and regional body fat mass (FM) measured by DXA were evaluated along with the serum concentration of 25-OH-D. Initial clinical pathology revealed hypoglycemia and reduced ionized serum calcium, and imaging, including computed tomography, did not lead to a diagnosis. The purpose of these experiments was to explore the hypothesis that the effects of nicotine on anxiety depend on the time since administration and the duration of treatment. In addition, knockdown of VASH1 in cancer cells promoted cell growth, adhesion and migration in vitro, and enhanced tumorigenesis and metastasis in vivo. To do this, we compared the SI of the middle cerebral artery (MCA) on magnetic resonance angiography (MRA) and the rCBF on SPECT. Cytoplasmic dynein and LIS1 are required for microtubule advance during growth cone remodeling and fast axonal outgrowth. Computerized tomography of the orbit and optic nerve canals in optic nerve atrophy of diverse etiology.

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