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Antram (Tramadol)

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Antram is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain. Antram is used to treat moderate to severe pain in adults. The extended-release form of Antram is for around-the-clock treatment of pain. This form of Antram is not for use on an as-needed basis for pain.

Other names for this medication:
Acuvin, Admadol, Cradol, Euphodol, Jpdol, Mydol, Nictram, Ondol, Painadol, Ramax, Redimol, Relidol, Rimol, Ryzolt, Sedate, Servodol, Traceta, Tramadex, Tramadol, Tramaflam, Tramataur, Tramazac, Tramazol, Tramol, Tramospas, Trapidol, Trofel, Trugesic, Victadol, Xtram

Similar Products:
Wellbutrin, Astelin, Medrol, Retin, Requip

Also known as: Tramadol


{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.


Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Antram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Antram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Antram dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.


Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Antram ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Antram ER should not be given to a child younger than 12 years old. Antram ER should not be given to anyone younger than 18 years old.

Do not give Antram ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Antram ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Antram ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Antram ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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C2 area neurostimulation: a surgical treatment for fibromyalgia. While the numbers and ratios of different immune subpopulations are analyzed after chemotherapy, changes to immune status after each cycle of treatment are less studied and remain unclear. Reasons for BioLINCC data request, research project plans, interactions with original study investigators, BioLINCC experience and other project details. The principal aim of this study is to provide an account of variation in UK undergraduate medical assessment styles and corresponding standard setting approaches with a view to highlighting the importance of a UK national licensing exam in recognizing a common standard. This review describes the level of evidence for the use of medical simulation in anesthesia. Luciferase reporter assays, quantitative RT-PCR and Western blotting were used to validate the target of miR-99a.

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Relationship between cardiac vagal activity and mood congruent memory bias in major depression. Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases. Maize rgh3 mutants have aberrant endosperm cell differentiation and proliferation. The present data give practical dietary means at the population level for the elimination of prediabetic conditions. N-Methyl-D-aspartate (NMDA) receptors play a critical role in many cortical functions and are implicated in several neuropsychiatric diseases. The clinicopathological study of such a case occurring in the retroperitoneal space of a 53-year-old man is herein reported. Benefits and disadvantages of both methods are under consideration. A central region model (CRM) cyclotron was built for various experimental verifications for the CYCIAE-100 project and for research and development of high current injection to accelerate milliampere H(-) beam. In the ipsilateral hemisphere, the middle-latency components (70-100 ms in latency), the dipoles of which were estimated to be in the second sensory cortex (SII), were markedly decreased in amplitude by both the visual and auditory stimulation.

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A survey of reflux-associated illnesses in the head and neck area. Thus, the monophenols are converted into diphenols, but the order of specificities towards monophenols is different to that of o-diphenols. Various tests can help orient the clinical diagnosis, but the confirmatory test is still the post mortem analysis. Urban Enhancement of PM10 Bioaerosol Tracers Relative to Background Locations in the Midwestern United States. To this aim, a large population of virtual subjects is created by a validated mathematical model of the cardiovascular system. State of dispersed lipid carrier and interface composition as determinants of beta-carotene stability in oil-in-water emulsions. However, none of the strains displayed increased fitness under acidic conditions or showed enhanced acid shock survival in the presence of urea. However, Wada tests are still performed, albeit in a considerably smaller number of patients at many epilepsy centres. The result of tissue specific expression analysis demonstrated that OsRbohD was expressed only in spike and calli, and OsRbohE and OsRbohF were only expressed in calli. Kerasoft IC compared to Rose-K in the management of corneal ectasias.

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Neutralization of measles virus wild-type isolates after immunization with a synthetic peptide vaccine which is not recognized by neutralizing passive antibodies. Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia. Complex coronary stenosis is associated with higher prevalence of acute coronary syndrome in acute clinical stage while simple coronary stenosis is associated with higher prevalence of previous acute coronary syndrome. In conclusion, the results confirm that the nuclear activity of VMH neurons underlies pineal influences. The goal was to compare the diagnostic performance of perfusion-CMR and SPECT for the detection of coronary artery disease (CAD) using conventional X-ray coronary angiography (CXA) as the reference standard. When both rat BMSCs and quail proepicardia (PEs) were seeded onto a three-dimensional (3-D) tubular scaffold engineered from aligned collagen type I strands and co-cultured in osteogenic media, the maturation and co-differentiation into osteoblastic and vascular cell lineages were observed. In the present study, tripelennamine and all of the optical isomers of chlorpheniramine, but not pyrilamine, produced a significant place preference.

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The Israeli Law of Freedom of Information 1998--implications with respect to the healthcare system. Only one paper describes losing sites, gaining sites, and sites showing exacerbation/remission patterns of change. Early use of HAs until the CI operation may result in better language perception and academic achievement among CI users with prelingual deafness. Therefore, we concluded that the Modified PMUE kills carcinoma cells sensitive to the agents and allows carcinoma cells resistant to the agents to grow. Male odor preference returned after vehicle treatment in counterbalanced tests. Structural analysis of human profilin has revealed two tryptophan residues, W3 and W31, which interact with polyproline. In a previous study, we have found bioactive peptide CSN1S2 from Ethawah goat milk for anti-inflammatory for repair the ileum destruction. Gastrointestinal (GI) disorders are prevalent in the cohort of children with ASD and they have been recognized as a comorbid condition recently. The aim of this study was to verify the capability of such a model to predict the distribution of the blood flow into the pulmonary arteries, by comparison with in vivo velocity measurements. Mutualisms are of fundamental importance in all ecosystems but their very existence poses a series of challenging evolutionary questions.

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This work reports as well some of the most important proposals of cellular response of cells affected by shear injuries, and how other stress response mechanisms allow the cell to respond to the hydrodynamic effects. The aminoglycoside antibiotic kanamycin damages DNA bases in Escherichia coli: caffeine potentiates the DNA-damaging effects of kanamycin while suppressing cell killing by ciprofloxacin in Escherichia coli and Bacillus anthracis. This study aims to investigate whether tadalafil accelerates fracture healing with an efficiency equal to that of sildenafil. Lewis(x)-containing oligosaccharide attenuates schistosome egg antigen-induced immune depression in human schistosomiasis. However, both free and conjugated estradiol were competent arresting the mitogenic activity promoted by insulin. A retrospective analysis of all patients attending the Toronto Congenital Cardiac Centre for Adults over three corresponding three month periods in 1987, 1992, and 1997. Death-associated protein kinase (DAPK) is a unique multidomain kinase acting both as a tumor suppressor and an apoptosis inducer. We aimed to assess the effect of informational video based on role-play modelling on preoperative anxiety and postoperative behavior changes in children undergoing surgery. The dependence of the prostate hyperplasia risks progression with the level of serum testosterone was found. The association between fatty replacement of rotator cuff and hemiplegic upper extremity function has not been defined yet.

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There is a disproportional prenatal ultrasound detection rate between severe and mild phenotypes, possibly due to the neglect of imaging of full bladders with a focus on neural tube defects. Using modern surgical treatment on patients that live in rural areas, with cataract and glaucoma is not sufficient. The worsening of drug abuse by drug-associated social interaction is a well-studied phenomenon. Frameworks that consider the role of enablers in HIV and AIDS programs were systematically reviewed to develop a conceptual model of interaction. People with this form of the condition have the external sex characteristics of females, but do not have a uterus and therefore do not menstruate and are unable to conceive a child (infertile). Together, these data suggest that phosphorylation of Ser(357) mediates at least in part the adverse effects of PKC-delta activation on insulin action. A zovirax 800 mg dosing total of 684 adults with axial myopia from -4.5 diopters (D) to -22 D were enrolled: 662 in the primary analysis group and 22 under compassionate use protocol expansion.

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We have investigated the conformational preferences of a newly synthesized C(alpha,alpha) symmetrically disubstituted glycine, namely alpha,alpha-dicyclopropylglycine (Dcp). Although the number of inpatient beds in use declined by one-third over the period and the national population grew by nearly one-fifth, discharge volumes increased significantly and rates of inpatient admission were maintained, as were access levels for vulnerable groups. Persistent crying as predominant manifestation of sepsis in infants and newborns. qMRI changes were more prominent than what class of medication is fenofibrate cortical atrophy, showing the potential of qMRI techniques to quantify microstructural alterations that remain undetected by conventional MRI. The mean total ischemia time was 88 (range 30-140) minutes in the hemi-hepatic occlusion group, and 68 (range 10-187) minutes in the total occlusion group. Compartmentation protects trypanosomes from the dangerous design of glycolysis. Trajectories were reconstructed manually and kinematics were determined using the (x, y) co-ordinates of each track point. The prevalence of diagnoses associated with chronic neuropathic pain was 13 per 1000, with the elderly, women and white patients experiencing the greatest burden of disease. In gastric cancer patients chronological and biological age might vary greatly between patients.

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I examined the association between everyday racial discrimination and depressive symptoms and explored the moderating role of 2 dimensions of masculine role norms, restrictive emotionality and self-reliance. The integrated management of surface water and groundwater for drinking and irrigation is to solve the water issues. In a 1-year initiation-promotion study, groups of 30 female SENCAR mice received an initiating dose of 50 mg kg(-1) 1,2-dihydro-2,2,4-trimethylquinoline followed by promotion with 12-O-tetradecanoylphorbol-13-acetate (TPA), or an initiating dose of 7,12-dimethylbenzanthracene (DMBA) followed by promotion with 5, 10 or 25 mg kg(-1) 1,2-dihydro-2,2,4-trimethylquinoline. In addition, the increased presence of G-CSF, CCL17, and CXCL10 was confirmed by ELISA in supernatants of neutrophils from CF patients. The Effect of World Trade Center Exposure on the Timing of Diagnoses of Obstructive Airway Disease, Chronic Rhinosinusitis, and Gastroesophageal Reflux Disease. The inclusion of sex as a biological variable in research is absolutely essential for improving our understanding of disease mechanisms contributing to risk and resilience. In this work, evidence is presented that nitrogenases isolated from Azotobacter vinelandii and Clostridium pasteurianum can hydrolyze MgGTP, MgITP, and MgUTP to can dogs take zyrtec allergy medicine their respective nucleoside diphosphates at rates comparable to those measured for MgATP hydrolysis. Neither had other malformations and were of normal intelligence.

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The survey asked for staff, techniques and quality criteria, which enabled a comparison to previous data from 1999 and surveys from other countries. A comparative study with available bench marking reveals that the hypothesis of electrophilicity and equalization, and the present method of evaluating equalized electrophilicity, are scientifically promising. Overall, few differences were found with respect to organ donation myths across the three ethnic groups. Mammary Analogue Secretory Carcinoma of what does zyrtec pills look like Salivary Glands: Molecular Analysis of 25 ETV6 Gene Rearranged Tumors With Lack of Detection of Classical ETV6-NTRK3 Fusion Transcript by Standard RT-PCR: Report of 4 Cases Harboring ETV6-X Gene Fusion. Of particular concern is the high global prevalence of vitamin B12 depletion, which is associated with low animal source food intake. Those with a reading of less than 0.9 should be directed for further vascular evaluation. Attentional performance, impulsivity, and related neurotransmitter systems in apoE2, apoE3, and apoE4 female transgenic mice. Postnatal development of the small intestinal mucosa drives age-dependent, regio-selective susceptibility to Escherichia coli K1 infection. Intraocular Pressure Changes during Accommodation in Progressing Myopes, Stable Myopes and Emmetropes. Beta-alanine release from the adult and developing hippocampus is enhanced by ionotropic glutamate receptor agonists and cell-damaging conditions.

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Corpus uteri cancer is the most common malignancy of the female reproductive tract in industrialized countries, and its incidence is increasing. Research in this area has focused on the incremental benefits of CT within the context of evolving diagnostic algorithms and in conjunction with techniques such as laparoscopy, endoscopy, and angiographic intervention. The method involves the determination of activation energy required for the flow process directly from the MD trajectory information and then calculate the important transport properties of the confined fluid from the activation energy. Numerous RCTs on cupping therapy have been conducted and published during the past decades. Our previous studies indicate that DPT possesses both anti-angiogenic and vascular-disrupting activities. Our study has not supported an association between anti-beta2GP1 and CAD. Various factors were analyzed, including the aneurysm location and size as well as the associated risk factors. During surgery, a huge multicystic lesion with a thick wall, covering the entire parietal and visceral pleura was found, which was subsequently proven to be a cystic cavernous lymphangioma. Using density functional theory and scanning probe microscopy results, we find that the accepted structural model for the well known bitartrate on Cu(110) chiral system cannot account for the chiral segregation observed.

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