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Antram (Tramadol)
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Antram

Antram is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain. Antram is used to treat moderate to severe pain in adults. The extended-release form of Antram is for around-the-clock treatment of pain. This form of Antram is not for use on an as-needed basis for pain.

Other names for this medication:
Acuvin, Admadol, Cradol, Euphodol, Jpdol, Mydol, Nictram, Ondol, Painadol, Ramax, Redimol, Relidol, Rimol, Ryzolt, Sedate, Servodol, Traceta, Tramadex, Tramadol, Tramaflam, Tramataur, Tramazac, Tramazol, Tramol, Tramospas, Trapidol, Trofel, Trugesic, Victadol, Xtram

Similar Products:
Wellbutrin, Astelin, Medrol, Retin, Requip

Also known as: Tramadol

Description

{name} (tramadol) is a pain medicine similar to an opioid. It acts in the central nervous system (CNS) to relieve pain.

{name} is used to treat moderate to severe pain in adults.

The extended-release form of tramadol ({name} ER) is for around-the-clock treatment of pain. {name} ER is not for use on an as-needed basis for pain.

Dosage

Usual Adult Dose for Pain:

Adults (17 years or older): 50 to 100 mg orally every 4 to 6 hours as needed for pain -For patients not requiring rapid onset of analgesic effect: Initial dose: 25 mg orally once a day; titrate in 25 mg increments every 3 days to reach a dose of 25 mg four times a day; thereafter increase by 50 mg as tolerated every 3 days Maximum dose: 400 mg per day.

Usual Adult Dose for Chronic Pain:

Extended-Release (ER): 18 years or older (tramadol-naive): 100 mg orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day For patients CURRENTLY receiving Immediate-Release (IR) Antram: Initial Dose: Calculate 24-hour IR requirement and initiate with a total daily ER dose rounded down to the next lowest 100 mg increment orally once a day Conversion from OTHER Opioids: Discontinue all other around the clock opioid drugs prior to initiating therapy -Initial dose: 100 mg ER orally once a day -Individually titrate in 100 mg increments every 5 days to an effective dose that minimizes adverse reactions -Maximum Dose: 300 mg/day.

Usual Geriatric Dose for Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Geriatric Dose for Chronic Pain:

Dose selection should be cautious generally starting at the low end of the dose range Over 75 years: Maximum dose of Immediate-release: 300 mg per day.

Usual Pediatric Dose for Pain:

Antram is not recommended for use in pediatric patients 17 years or older: See Adult Dose.

Detailed Antram dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include severe drowsiness, pinpoint pupils, slow breathing, or no breathing.

Your doctor may recommend you get naloxone (a medicine to reverse an opioid overdose) and keep it with you at all times. A person caring for you can give the naloxone if you stop breathing or don't wake up. Your caregiver must still get emergency medical help and may need to perform CPR (cardiopulmonary resuscitation) on you while waiting for help to arrive.

Anyone can buy naloxone from a pharmacy or local health department. Make sure any person caring for you knows where you keep naloxone and how to use it.

Storage

Store at a room temperature between 4 and 30 degrees C (39 and 86 degrees F) away from moisture, light and heat. Throw away the after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Antram are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Antram ER if you are allergic to it, or if you have:

severe asthma or breathing problems; a stomach or bowel obstruction (including paralytic ileus); if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications; or if you have used an MAO inhibitor in the past 14 days (such as isocarboxazid, linezolid, methylene blue injection, phenelzine, or tranylcypromine).

Antram ER should not be given to a child younger than 12 years old. Antram ER should not be given to anyone younger than 18 years old.

Do not give Antram ER to anyone younger than 18 years old who recently had surgery to remove the tonsils or adenoids.

Seizures have occurred in some people taking Antram ER. Your seizure risk may be higher if you have ever had:

a head injury, epilepsy or other seizure disorder; drug or alcohol addiction; or a metabolic disorder.

Tell your doctor if you have ever had:

breathing problems, sleep apnea; liver or kidney disease; urination problems; problems with your gallbladder, pancreas, or thyroid; a stomach disorder; or mental illness, or suicide attempt.

If you use Antram ER during pregnancy, your baby could be born with life-threatening withdrawal symptoms, and may need medical treatment for several weeks.

Ask a doctor before using Antram ER if you are breastfeeding. Tell your doctor if you notice severe drowsiness or slow breathing in the nursing baby.

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Relationship between cardiac vagal activity and mood congruent memory bias in major depression. Invasive ability of human renal cell carcinoma cell line Caki-2 is accelerated by gamma-aminobutyric acid, via sustained activation of ERK1/2 inducible matrix metalloproteinases. Maize rgh3 mutants have aberrant endosperm cell differentiation and proliferation. The present data give practical dietary means at the population level for the elimination of prediabetic conditions. N-Methyl-D-aspartate (NMDA) receptors play a critical role in many cortical functions and are implicated in several neuropsychiatric diseases. The clinicopathological study of such a case occurring in the retroperitoneal space of a 53-year-old man is herein reported. Benefits and disadvantages of both methods are under consideration. A central region model (CRM) cyclotron was built for various experimental verifications for the CYCIAE-100 project and for research and development of high current injection to accelerate milliampere H(-) beam. In the ipsilateral hemisphere, the middle-latency components (70-100 ms in latency), the dipoles of which were estimated to be in the second sensory cortex (SII), were markedly decreased in amplitude by both the visual and auditory stimulation.

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A survey of reflux-associated illnesses in the head and neck area. Thus, the monophenols are converted into diphenols, but the order of specificities towards monophenols is different to that of o-diphenols. Various tests can help orient the clinical diagnosis, but the confirmatory test is still the post mortem analysis. Urban Enhancement of PM10 Bioaerosol Tracers Relative to Background Locations in the Midwestern United States. To this aim, a large population of virtual subjects is created by a validated mathematical model of the cardiovascular system. State of dispersed lipid carrier and interface composition as determinants of beta-carotene stability in oil-in-water emulsions. However, none of the strains displayed increased fitness under acidic conditions or showed enhanced acid shock survival in the presence of urea. However, Wada tests are still performed, albeit in a considerably smaller number of patients at many epilepsy centres. The result of tissue specific expression analysis demonstrated that OsRbohD was expressed only in spike and calli, and OsRbohE and OsRbohF were only expressed in calli. Kerasoft IC compared to Rose-K in the management of corneal ectasias.

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Neutralization of measles virus wild-type isolates after immunization with a synthetic peptide vaccine which is not recognized by neutralizing passive antibodies. Parry-Romberg syndrome with ipsilateral hemipons involvement presenting as monoplegic ataxia. Complex coronary stenosis is associated with higher prevalence of acute coronary syndrome in acute clinical stage while simple coronary stenosis is associated with higher prevalence of previous acute coronary syndrome. In conclusion, the results confirm that the nuclear activity of VMH neurons underlies pineal influences. The goal was to compare the diagnostic performance of perfusion-CMR and SPECT for the detection of coronary artery disease (CAD) using conventional X-ray coronary angiography (CXA) as the reference standard. When both rat BMSCs and quail proepicardia (PEs) were seeded onto a three-dimensional (3-D) tubular scaffold engineered from aligned collagen type I strands and co-cultured in osteogenic media, the maturation and co-differentiation into osteoblastic and vascular cell lineages were observed. In the present study, tripelennamine and all of the optical isomers of chlorpheniramine, but not pyrilamine, produced a significant place preference.

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Absorbed dose measurements were obtained after every 5 panoramic exposures of a 25-exposure total. These results indicated that the formation of aldehydes in oxygen was due to nonenzymatic reactions. Presently, rabbits and pigs are favored for the former two areas of study, and dogs and sheep appear to provide suitable models for testing devices for endoluminal repair of aneurysms. The C-terminal Cytosolic Region of Rim21 Senses Alterations in Plasma Membrane Lipid Composition: INSIGHTS INTO SENSING MECHANISMS FOR PLASMA MEMBRANE LIPID ASYMMETRY. Clinical and analytical data of the subjects were evaluated at baseline and after treatment. Awareness of the risk factors for leptospirosis, mainly that of the exposure to contaminated fresh water after a flooding, would lead to an early and appropriate treatment before the confirmed diagnosis. It is therefore not surprising that a defect in NO activity is thought to play a role in the pathogenesis of both erectile dysfunction and ischaemic heart disease. The measurement results are in quantitative agreement with a simple model that is based on the Boltzmann transport equation.

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The Israeli Law of Freedom of Information 1998--implications with respect to the healthcare system. Only one paper describes losing sites, gaining sites, and sites showing exacerbation/remission patterns of change. Early use of HAs until the CI operation may result in better language perception and academic achievement among CI users with prelingual deafness. Therefore, we concluded that the Modified PMUE kills carcinoma cells sensitive to the agents and allows carcinoma cells resistant to the agents to grow. Male odor preference returned after vehicle treatment in counterbalanced tests. Structural analysis of human profilin has revealed two tryptophan residues, W3 and W31, which interact with polyproline. In a previous study, we have found bioactive peptide CSN1S2 from Ethawah goat milk for anti-inflammatory for repair the ileum destruction. Gastrointestinal (GI) disorders are prevalent in the cohort of children with ASD and they have been recognized as a comorbid condition recently. The aim of this study was to verify the capability of such a model to predict the distribution of the blood flow into the pulmonary arteries, by comparison with in vivo velocity measurements. Mutualisms are of fundamental importance in all ecosystems but their very existence poses a series of challenging evolutionary questions.

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This work reports as well some of the most important proposals of cellular response of cells affected by shear injuries, and how other stress response mechanisms allow the cell to respond to the hydrodynamic effects. The aminoglycoside antibiotic kanamycin damages DNA bases in Escherichia coli: caffeine potentiates the DNA-damaging effects of kanamycin while suppressing cell killing by ciprofloxacin in Escherichia coli and Bacillus anthracis. This study aims to investigate whether tadalafil accelerates fracture healing with an efficiency equal to that of sildenafil. Lewis(x)-containing oligosaccharide attenuates schistosome egg antigen-induced immune depression in human schistosomiasis. However, both free and conjugated estradiol were competent arresting the mitogenic activity promoted by insulin. A retrospective analysis of all patients attending the Toronto Congenital Cardiac Centre for Adults over three corresponding three month periods in 1987, 1992, and 1997. Death-associated protein kinase (DAPK) is a unique multidomain kinase acting both as a tumor suppressor and an apoptosis inducer. We aimed to assess the effect of informational video based on role-play modelling on preoperative anxiety and postoperative behavior changes in children undergoing surgery. The dependence of the prostate hyperplasia risks progression with the level of serum testosterone was found. The association between fatty replacement of rotator cuff and hemiplegic upper extremity function has not been defined yet.

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Corpus uteri cancer is the most common malignancy of the female reproductive tract in industrialized countries, and its incidence is increasing. Research in this area has focused on the incremental benefits of CT within the context of evolving diagnostic algorithms and in conjunction with techniques such as laparoscopy, endoscopy, and angiographic intervention. The method involves the determination of activation energy required for the flow process directly from the MD trajectory information and then calculate the important transport properties of the confined fluid from the activation energy. Numerous RCTs on cupping therapy have been conducted and published during the past decades. Our previous studies indicate that DPT possesses both anti-angiogenic and vascular-disrupting activities. Our study has not supported an association between anti-beta2GP1 and CAD. Various factors were analyzed, including the aneurysm location and size as well as the associated risk factors. During surgery, a huge multicystic lesion with a thick wall, covering the entire parietal and visceral pleura was found, which was subsequently proven to be a cystic cavernous lymphangioma. Using density functional theory and scanning probe microscopy results, we find that the accepted structural model for the well known bitartrate on Cu(110) chiral system cannot account for the chiral segregation observed.

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Nevertheless, given the low infective dose of this pathogen and the deep-rooted tradition of consuming raw or undercooked beef, the current prevalence should not be considered lightly from a public health perspective. One operation on one side was counted as one case and the patients were divided into two groups. Patients with a transient ischemic attack and an acute stroke need urgent investigations and therapy in a stroke unit. Notably, autophagy is a highly conserved cellular process among eukaryotes, and the yeast Saccharomyces cerevisiae has become a universal model system for unraveling the molecular machinery underlying autophagic mechanisms. Hong-Ou-Mandel interference mediated by the magnetic plasmon waves in a three-dimensional optical metamaterial. Unlike aesthetic patients in the West, who usually seek to improve the signs of aging, Asian patients are younger and request a broader range of indications. Nanometer-size systems have been extensively investigated for delivering genes at both local and systemic levels. Patients were randomized to 500 mg intraoperative methylprednisolone or placebo.

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