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Anxionil (Lorazepam)
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Anxionil

Anxionil belongs to a group of drugs called benzodiazepines. Lorazepam affects chemicals in the brain that may be unbalanced in people with anxiety. Anxionil is used to treat anxiety disorders. Anxionil may also be used for purposes not listed in this medication guide.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Aldactone, Pamelor, Robaxin, Hydrea, Zetia, Leukeran, Lodine, Starlix

Also known as: Lorazepam

Description

{name} (lorazepam) belongs to a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). It is thought that lorazepam works by enhancing the activity of certain neurotransmitters in the brain.

{name} is a prescription medicine used to treat anxiety disorders.

It is dangerous to purchase {name} on the Internet or outside the United States. The sale and distribution of medicines outside the U.S. does not comply with safe-use regulations of the Food and Drug Administration (FDA). These medications may contain dangerous ingredients, or may not be distributed by a licensed pharmacy.

Dosage

Usual Adult Dose for Anxiety:

Initial dose: 2 to 3 mg orally per day, given 2 to 3 times per day Maintenance dose: 1 to 2 mg orally 2 to 3 times a day Comments: -The daily dosage may vary from 1 to 10 mg/day. -The dosage should be increased gradually when needed to help avoid adverse effects. -When higher dosage is indicated, the evening dose should be increased before the daytime doses. -Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Uses: -Management of anxiety disorders -Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

Usual Adult Dose for Insomnia:

2 to 4 mg orally once a day at bedtime Comments: -The dosage should be increased gradually when needed to help avoid adverse effects. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Use: Management of insomnia due to anxiety of transient situational stress

Usual Geriatric Dose for Anxiety:

Older or debilitated patients: -Initial dose: 1 to 2 mg orally per day, given in divided doses Comments: -The dosage should be increased gradually when needed to help avoid adverse effects. -The daily dosage may vary from 1 to 10 mg/day. -When higher dosage is indicated, the evening dose should be increased before the daytime doses. -Use of anxiolytic agents is typically not needed to treat anxiety/tension associated with the stress of everyday life. -Clinical studies have not evaluated this drug for efficacy in long-term treatment (e.g., greater than 4 months). Uses: -Management of anxiety disorders -Short-term relief of the symptoms of anxiety or anxiety associated with depressive symptoms

Detailed Anxionil dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of lorazepam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing.

Overdose symptoms may include extreme drowsiness, confusion, slurred speech, feeling restless, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, or coma.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Anxionil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Anxionil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

The additive central-nervous-system effects of other drugs, such as phenothiazines, narcotic analgesics, barbiturates, antidepressants, scopolamine, and monoamine-oxidase inhibitors, should be borne in mind when these other drugs are used concomitantly with or during the period of recovery from Anxionil Injection.

Extreme caution must be used when administering Anxionil Injection to elderly patients, very ill patients, or to patients with limited pulmonary reserve because of the possibility that hypoventilation and/or hypoxic cardiac arrest may occur. Resuscitative equipment for ventilatory support should be readily available.

When Anxionil injection is used IV as the premedicant prior to regional or local anesthesia, the possibility of excessive sleepiness or drowsiness may interfere with patient cooperation in determining levels of anesthesia. This is most likely to occur when greater than 0.05 mg/kg is given and when narcotic analgesics are used concomitantly with the recommended dose.

As with all benzodiazepines, paradoxical reactions may occur in rare instances and in an unpredictable fashion. In these instances, further use of the drug in these patients should be considered with caution.

There have been reports of possible propylene glycol toxicity (e.g., lactic acidosis, hyperosmolality, hypotension) and possible polyethylene glycol toxicity (e.g., acute tubular necrosis) during administration of Anxionil Injection at higher than recommended doses. Symptoms may be more likely to develop in patients with renal impairment.

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