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Aprin (Azathioprine)
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Aprin

Aprin is an immunosuppressant. It reduces the action of body's own defense system (the immune system) and prevents rejection of the transplanted organ. It also blocks the action of certain chemical messengers that are responsible for inflammation.

Other names for this medication:
Aprin, Azathioprine, Azimune, Azoprine, Azoran, Immuzat, Imuzat, Thiazprine, Transimune, Zinothin, Zioprin, Zymurine

Similar Products:
Casodex, Precose, Risperdal, Klonopin, Levitra, Rhinocort, Reminyl, Vantin

Also known as: Azathioprine

Description

Azathioprine injection is used to prevent rejection of a transplanted kidney. It belongs to the group of medicines known as immunosuppressive agents. Azathioprine will lower the body's natural immunity in patients who receive transplants to prevent rejection of the new kidney. It is also used to relieve joint pain and swelling for patients with active rheumatoid arthritis.

This medicine is to be given only by or under the direct supervision of your doctor.

Dosage

Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using Aprin.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

When given for kidney transplant, Aprin is usually given right before or on the day of transplant. For rheumatoid arthritis, this medicine is taken on a daily basis.

It may take up to 8 weeks before your symptoms improve. Keep using Aprin as directed and tell your doctor if your symptoms have not improved after 12 weeks of use.

Take with food if Aprin upsets your stomach.

You may not be able to continue taking other arthritis medications together with Aprin. Do not change your dose or dosing schedule without your doctor's advice.

Aprin affects your immune system. You may get infections more easily, even serious or fatal infections. Your doctor will need to examine you on a regular basis.

Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

Detailed Aprin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Aprin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Aprin if you are allergic to Aprin.

You should not use Aprin to treat rheumatoid arthritis if you are pregnant. This medicine can harm an unborn baby. Use effective birth control to prevent pregnancy while using this medicine.

Aprin may cause a rare type of lymphoma (cancer) of the liver, spleen, and bone marrow that can be fatal. This has occurred mainly in teenagers and young men with Crohn's disease or ulcerative colitis. However, anyone with an inflammatory autoimmune disorder may have a higher risk of lymphoma. Talk with your doctor about your own risk.

While taking Aprin, you may have a higher risk of developing skin cancer. Ask your doctor about skin symptoms to watch for.

Tell your doctor if you have ever had:

kidney disease, or a kidney transplant (if you are using Aprin for rheumatoid arthritis); any type of viral, bacterial, or fungal infection; liver disease; or chemotherapy with medications like cyclophosphamide, chlorambucil, melphalan, busulfan, and others.

You should not breast-feed while you are using Aprin.

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