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Aptogrel (Clopidogrel)
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Aptogrel

Aptogrel is an antiplatelet medication. It prevents your platelets from clumping together into blood clots. This can lower the risk of heart attack, since most heart attacks are caused by a clot forming in the vessels supplying your heart. Aptogrel also lowers the risk of stroke, since most strokes are caused by blood clots in the vessels supplying your brain.

Other names for this medication:
Aclotil, Adplatt, Aptogrel, Atheroz, Caplor, Carpigrel, Cenoza, Ceruvin, Clasprin, Clopicure, Clopilet, Clopione, Clopisa, Clopitab, Clopivas, Clopod, Cloprez, Clospir, Clotnil, Complatt, Deplatt, Neogrel, Pidgrel, Plagril, Starclop, Torplatt, Zogrell

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Also known as: Clopidogrel

Description

Aptogrel target is the treatment of heart attacks and strokes by preventing blood clots. It is also taken to prevent other heart or blood vessels disorders. Aptogrel is acting by preventing blood clots. It is antiplatelet agents. Aptogrel is also known as Clopidogrel, Clopitab, Caplor, Iscover, Clopilet, Ceruvin. Generic name of Aptogrel is Clopidogrel. Brand name of Aptogrel is Aptogrel.

Dosage

Usual Adult Dose for Acute Coronary Syndrome:

Unstable Angina (UA)/Non-ST-Elevation Myocardial Infarction (NSTEMI): -Loading dose: 300 mg orally once -Maintenance dose: 75 mg orally once a day -Duration of therapy: Optimal duration unknown. ST-Elevation Myocardial Infarction (STEMI): -Loading dose: 300 mg orally once (OPTIONAL) -Maintenance dose: 75 mg orally once a day, with or without thrombolytics -Duration of therapy: Optimal duration unknown. Comments: -Administer this drug in combination with aspirin 75 mg to 325 mg orally once a day. -The benefit of this drug for patients who undergo primary percutaneous coronary intervention is unknown. Uses: Prevention of atherothrombotic events in patients with non-ST-segment elevation acute coronary syndrome (UA, NSTEMI, those who are to be managed medically, those who are to be managed with coronary revascularization) and STEMI.

Usual Adult Dose for Ischemic Stroke:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Myocardial Infarction:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Peripheral Arterial Disease:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Detailed Aptogrel dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Aptogrel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Aptogrel if you are allergic to Aptogrel components. Do not take Aptogrel if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Aptogrel if you suffer from or have a history of stroke, stomach ulcer or ulcerative colitis; liver or kidney disease, hemophilia. Be careful with Aptogrel if you are taking such medicines as aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs such as naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ibuprofen (Motrin, Advil), (Toradol), ketoprofen (Orudis), nabumetone (Relafen), piroxicam (Feldene), ketorolac mefenamic acid (Ponstel), meloxicam (Mobic) and the others), phenytoin (such as Dilantin); torsemide (such as Demadex); medication used to prevent blood clots (alteplase (such as Activase), anistreplase (such as Eminase), dipyridamole (such as Persantine), streptokinase (such as Kabikinase, Streptase), ticlopidine (Ticlid) and urokinase (such as Abbokinase); fluvastatin (such as Lescol); a blood thinner (warfarin (such as Coumadin), heparin, ardeparin (such as Normiflo), dalteparin (such as Fragmin), danaparoid (such as Orgaran), enoxaparin (such as Lovenox), or tinzaparin (such as Innohep); tamoxifen (such as Nolvadex); tolbutamide (such as Orinase). It is not recommended to do sport while taking Aptogrel because it can cause bleeding or bruising injury. If you are going to have a surgery you should stop taking Aptogrel for 5 days before the surgery. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Aptogrel suddenly.

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The theoretical rationale for bursectomy was to reduce the risk of peritoneal recurrences by eliminating the peritoneum over the lesser sac, which might include free cancer cells or micrometastases. Magnetic resonance imaging (MRI) has been increasingly used for the purpose of identifying intricate organ sharing. To investigate the clinical characteristics, surgical interventions, and outcomes of arteriovenous fistula (AVF) aneurysms, we retrospectively analyzed patients on regular hemodialysis (HD). Indirect Haemagglutination Test in Comparison with ELISA for Detection of Antibodies against Invasive Amoebiasis. Baseline characteristics and treatment preferences of oral surgery patients. The available mechanistic and toxicokinetic evidence supports the hypothesis that male rat urinary bladder tumors arise through urinary bladder calculi formation but is insufficient to hypothesize a mode of action for liver tumors in female mice. Earlier, we discovered that the herpesvirus nuclear egress complex (NEC) could bud synthetic membranes in vitro without the help of other proteins by forming a coat-like hexagonal scaffold inside the budding membrane.

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Investigated molecular pathways are more profoundly affected by hyperglycemia that occurs before renal ischemia-reperfusion. Successful replacement of a detached pedestal during support with Jarvik 2000. We measured tensile strength and maximum intraluminal pressures. Seventy-three eyelids of 39 patients were subjected to upper lid blepharoplasty. Comparative efficacy and safety of first-line antiretroviral therapy for the treatment of HIV infection: a systematic review and network meta-analysis.

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