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Assepium (Trimethoprim)

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Assepium (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

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Actrim, Avlotrin, Bacta, Bacticel, Bactipront, Bakton, Balkatrin, Bascul, Biseptol, Bismoral, Chemitrim, Cotrimol, Cotrimox, Dhatrin, Diseptyl, Ditrim, Doctrim, Epitrim, Escoprim, Groprim, Groseptol, Ikaprim, Linaris, Megatrim, Navatrim, Primazole, Purbac, Septran, Septrin, Sigaprim, Sulbron, Sulfamethoxazol, Sulfametoxazol, Sulfoid, Sulphatrim, Sumetoprin, Supreme, Trimecor, Trimesulf, Trimethazol, Trimetoger, Trimezol, Trimoks, Trimol, Trimosazol, Xepaprim

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Also known as: Trimethoprim


{name} contains a combination of sulfamethoxazole and trimethoprim. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria.

{name} is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.


Prescribing Assepium (sulfamethoxazole and trimethoprim) tablets in the absence of a proven or strongly suspected bacterial infection or a prophylactic indication is unlikely to provide benefit to the patient and increases the risk of the development of drug-resistant bacteria.

Assepium should be given with caution to patients with impaired renal or hepatic function, to those with possible folate deficiency (e.g., the elderly, chronic alcoholics, patients receiving anticonvulsant therapy, patients with malabsorption syndrome, and patients in malnutrition states) and to those with severe allergies or bronchial asthma.

Hematological changes indicative of folic acid deficiency may occur in elderly patients or in patients with preexisting folic acid deficiency or kidney failure. These effects are reversible by folinic acid therapy.


If you overdose Generic Assepium and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Assepium overdosage: dizziness, drowsiness, nausea, vomiting, loss of appetite, stomach pain, headache, yellowing of your skin or eyes, blood in urine, fever, confusion, fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Assepium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Assepium if you are allergic to sulfamethoxazole or trimethoprim, or if you have:

severe liver disease; kidney disease that is not being treated or monitored; anemia (low red blood cells) caused by folic acid deficiency; a history of low blood platelets after taking trimethoprim or any sulfa drug; or if you take dofetilide (Tikosyn).

Do not use Assepium if you are pregnant. This medicine could harm the unborn baby or cause birth defects. Use effective birth control, and tell your doctor if you are pregnant or become pregnant.

Do not breastfeed while using this medicine.

This medicine should not be given to a child younger than 2 months old.

To make sure Assepium is safe for you, tell your doctor if you have:

kidney or liver disease; a folate (folic acid) deficiency; asthma or severe allergies; a thyroid disorder; malnourishment; alcoholism; high levels of potassium in your blood; porphyria, or glucose-6-phosphate dehydrogenase (G6PD) deficiency; or if you use a blood thinner (such as warfarin) and you have routine "INR" or prothrombin time tests.

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Fatty acids and production of tylosin-like compounds in Streptomyces fradiae. Demethylzeylasteral exhibits dose-dependent inhibitory behaviour towards estradiol glucuronidation. Oblique rotation in correspondence analysis: a step forward in the search for the depakote and alcohol simplest interpretation. There was a good success in 46 patients, in all patients satisfactory results could be registered. The binding of these systems to the mannose-binding protein Concanavalin A was compared using a hemagglutination assay. Two-step filtering approaches that reduce the number of polymorphisms tested for interactions can substantially increase the power of genome-wide gene-environment studies. The pediatrician plays important role in early diagnosis, management of medical complications, and psychological support to the patient and the family. I have a friend who swears it will help him avoid having a second heart attack. By monitoring spectral counts of specific hydroxamic acid signatures generated after the conversion of the ADP-ribose modification onto peptides by hydroxylamine hydrolysis, we undertook a thorough mass spectrometry mapping of the glutamate and aspartate ADP-ribosylation sites onto automodified PARP-1, PARP-2 and PARP-3.

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Finally, we show that co-administration of metformin also protects against cisplatin-induced peripheral neuropathy. Detection of the Emerging Picornavirus Senecavirus A in Pigs, Mice, and Houseflies. To set the scene we have briefly explored drugs that have failed in the clinic in order to identify possible targets that have been overlooked or underexploited. Recent reports have highlighted the occlusion of arteries, venules, and/or capillaries in bone tissue. Moreover, methyl violet 2B significantly inhibited FER kinase phosphorylation that activates FAK in cell. Azithromycin and survival in Streptococcus pneumoniae pneumonia: a retrospective study.

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