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Astepro (Azelastine)

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Astepro is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes. This medicine is available only with your doctor's prescription.

Other names for this medication:
Astepro, Azelast, Azelastine, Azenate, Duonase, Nazomac, Oculast, Optihist, Optivar

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Also known as: Azelastine


{name} (azelastine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

{name} nasal spray is used to treat sneezing, runny or stuffy nose, itching, and other nasal symptoms of allergies, in adults and children who are at least 5 years old.

{name} is also used to treat ongoing nasal symptoms (runny or stuffy nose, sneezing, itching) that are not caused by allergies, in adults and children who are at least 12 years old.


Use Astepro nasal spray exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Before you use Astepro Nasal Spray for the first time, you will need to prime the bottle.

Remove the blue dust cover over the tip of the pump and the blue safety clip just under the "shoulders" of the pump.

Hold the bottle upright with 2 fingers on the shoulders of the spray pump unit and put your thumb on the bottom of the bottle. Press upward with your thumb and release for the pumping action. Repeat this until you see a fine mist To get a fine mist you must pump the spray fast and use firm pressure against the bottom of the bottle. If you see a stream of liquid, the pump is not working correctly and you may have nasal discomfort This should happen in 4 sprays or less.

Now your pump is primed and ready to use.

Using your Astepro Nasal Spray.

Blow your nose to clear your nostrils. Keep your head tilted downward toward your toes. Place the spray tip about ¼ inch to ½ inch into 1 nostril. Hold bottle upright and aim the spray tip toward the back of your nose Close your other nostril with a finger. Press the pump 1 time and sniff gently at the same time, keeping your head tilted forward and down Repeat in your other nostril If your healthcare provider tells you to use 2 sprays in each nostril, repeat Steps 2 through 4 above for the second spray in each nostril Breathe in gently, and do not tilt your head back after using Astepro Nasal Spray. This will help to keep the medicine from going into your throat When you finish using your Astepro Nasal Spray, wipe the spray tip with a clean tissue or cloth. Put the safety clip and dust cover back on the bottle.

Avoid getting this medicine in your eyes or mouth.

Do not allow a young child to use Astepro without help from an adult.

Call your doctor if your symptoms do not improve, or if they get worse.

Store this medicine in an upright position at room temperature. Do not freeze.

Throw away the medicine after you have used 200 sprays, even if there is still medicine left in the bottle.

Detailed Astepro dosage information


An overdose of azelastine nasal is not expected to be dangerous. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medication.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Store the bottle upright with the pump tightly closed.

Detailed Astepro dosage information

Side effects

The most common side effects associated with Astepro are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of Astepro® nasal spray in the elderly. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

No information is available on the relationship of age to the effects of Astepro® allergy nasal spray in geriatric patients.

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