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Astic (Ticlopidine)
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Astic

Astic is an antiplatelet drug that targets the P2Y12 receptor of platelets. Astic is taken orally and is a prodrug that must be metabolically activated before it can be effective. It first enters the liver and enters the endoplasmic reticulum where it is metabolized to form the active metabolite.

Other names for this medication:
Aplaket, Astic, Taispin, Ticlantin, Ticlobest, Ticlogard, Ticlogaurd, Ticlop, Ticlopid, Ticlopidine, Ticlovas, Tikla, Tikleen, Tilkon, Tyklid

Similar Products:
Minocin, Zanaflex, Neoral, Fulvicin, Detrol, Cenforce, Actos, Mysoline, Hytrin

Also known as: Ticlopidine

Description

Ticlopidine is used to lessen the chance of having a stroke. It is given to people who have already had a stroke and to people with certain medical problems that may lead to a stroke. Because ticlopidine can cause serious side effects, especially during the first 3 months of treatment, it is used mostly for people who cannot take aspirin to prevent strokes.

A stroke may occur when blood flow to the brain is interrupted by a blood clot. Ticlopidine reduces the chance that a harmful blood clot will form, by preventing certain cells in the blood from clumping together. This effect of ticlopidine may also increase the chance of serious bleeding in some people.

This medicine is available only with a doctor's prescription.

Dosage

Ticlopidine should be taken with food. This increases the amount of medicine that is absorbed into the body. It may also lessen the chance of stomach upset.

Take this medicine only as directed by your doctor. Ticlopidine will not work properly if you take less of it than directed. Taking more ticlopidine than directed may increase the chance of serious side effects without increasing the helpful effects.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For prevention of strokes: Adults—1 tablet (250 mg) two times a day, with food. Children—It is not likely that ticlopidine would be used to help prevent strokes in children. If a child needs this medicine, however, the dose would have to be determined by the doctor. For prevention of strokes or heart attack following heart stent procedure: Adults—1 tablet (250 mg) two times a day, with food together with your doctor's recommended dose of aspirin for up to 30 days following the procedure Children—It is not likely that ticlopidine would be used to help prevent strokes or heart attack in children. If a child needs this medicine, however, the dose would have to be determined by the doctor

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Astic can be fatal.

Overdose symptoms may include irregular heartbeats, feeling restless or agitated, confusion, severe sweating, slow or jerky muscle movements, extreme drowsiness, slow breathing, feeling like you might pass out, seizure, or coma.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Astic dosage information

Side effects

The most common side effects associated with Astic are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Pathological and biochemical studies of acute anoxia in newborns. Then the pattern recognition methods (HMM, GMM and SVM) were used to distinguish the mixed data into categories of normal and pathological speech. Twelve of these were analysed using best-fit framework synthesis, with the CHIME model of recovery providing the exploratory framework. The development of resistances to therapeutic agents and the absence of targeted therapy for triple negative breast cancer motivate the search for alternative treatments. Multiple pulmonary nodules in AIDS: usefulness of CT in distinguishing among potential causes. Our findings also suggested that by binding to the Hck SH3 domain, Nef indirectly affects the conformation of the kinase active site to favor inhibitor association. Systemic elevation of PTEN induces a tumor-suppressive metabolic state. Few effective community-based interventions exist to increase HIV testing and uptake of antiretroviral therapy (ART) in pregnant women in hard-to-reach resource-limited settings. Examination of nuclear morphology revealed more cells with apoptotic features upon treatment with chelerythrine and sanguinarine, but not chelidonine. The peritrochanteric and deep gluteal regions represent 2 of the most currently active areas of exploration.

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The crystal structure of Zika virus NS5 reveals conserved drug targets. elegans after sustaining trauma that required tissue debridement because of tissue necrosis. This is complemented by a checklist that early diagnosis researchers can use when designing and conducting studies in this field. We apply and atarax pills assess the utility of a Climate Change Vulnerability Index on 3 focal species using distribution or niche modeling frameworks. We present the case of a 56-year-old postmenopausal woman who underwent bilateral breast reduction and developed galactorrhea 2 months postoperatively.

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