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Atenerate (Nifedipine)

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Atenerate is a dihydropyridine calcium channel blocker. Atenerate is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Atenerate was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Atenerate works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adipine, Calcianta, Calcigard, Cardifen, Cardiosol, Cardipin, Cardules, Casanmil, Cordilat, Corotrend, Farmalat, Glopir, Lemar, Nelapine, Nifangin, Nifebene, Nifecor, Nifedical, Nifedicor, Nifedine, Nifedip, Nifedipinum, Nifehexal, Nifensar, Nifin, Pabalat, Pressolat, Viscard

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Atenerate PA 10. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Atenerate and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nifedipine dosage information

Side effects

The most common side effects associated with Atenerate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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The addition of 5-HT (2 mg/ml) to the culture medium significantly increased the crypt cell production rate (p less than 0.001), suggesting that this amine may have a trophic effect on crypt cells in vitro. Maltose which acted as inducer for the TM system acted as a corepressor for the MD system intensifying repression. Placental HIF-1 alpha, HIF-2 alpha, membrane and soluble VEGF receptor-1 proteins are not increased in normotensive pregnancies complicated by late-onset intrauterine growth restriction. To investigate the effect of glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide on hypoxia/reoxygenation (H/R)-induced cardiomyocytes death under high glucose condition and the potential mechanisms. It also plays an important role in lymphatic metastasis of esophageal squamous cancer and tumor malignancy degree. For spacer applications in which limited weight-bearing is anticipated, the hip prosthesis construct appears more efficacious, but its pros and cons should be compared with those of the commercial product. Exposure of cultured astrocytes to Al chloride (200, 400, and 800 microM) specifically increased glutamine synthetase activity for the three concentrations tested. Patients were included in the study when radiographs at the time of surgery showed that only the crown of the germ was formed.

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Successful local fibrinolytic therapy for arm vein thrombosis in antiphospholipid syndrome secondary to systemic lupus erythematosus. These are a group of prelymphomatous or prelymphomogenic clinicopathologic entities in which proliferation of a lymphoid element (cell) is coupled with the accelerated development of blood capillaries and postcapillary venules. Chewing simulator, thermocycler, fatigue, implant-supported hybrid prosthesis, acrylic teeth, fracture, metal structure design. porcinum isolated from a patient with impairments in IL-12/IFN-gamma pathway. We assessed the overall quality of evidence for each combination of intervention and outcome using the GRADE approach. The aim of this study was to characterise and compare the functional defects caused by the six published missense mutations that affect mature SPINK1-namely, N34S, D50E, Y54H, P55S, R65Q, and R67C. The data of 105 patients with epithelioid cell granulomas in biopsy tissue who had undergone the bronchoscopic lung biopsy or bronchial biopsy at the Centre of Pulmonology and Allergology of Vilnius University Hospital Santariski klinikos (Vilnius, Lithuania) were examined.

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To characterise the time course of changes in elbow neuromuscular properties in hemiparetic stroke survivors over a 1 year period. Pros and cons of barium-impregnated polyethylene spheres in gastrointestinal disease. An anatomic biomechanical study was performed on 10 dentate human cadaver heads using tooth-borne and bone-borne distraction devices. Urine protein excretion patterns have been studied in 42 patients with sepsis and compared with that in 21 healthy controls. We summarize here recent progress in predicting the 3-dimensional (3D) structure of G protein-coupled receptors (GPCR) and in predicting the binding sites for various agonists and antagonists. Microfluidic devices have the potential to transform single-cell analysis from a major technological challenge task to a relatively routine procedure for research and clinical assays. A complex pattern of spliced and unspliced PMCHL RNAs were found in human brain and testis. Since residual pesticide levels were 17/10,000-2/5 of ADI, all the rice samples were considered to be safe for human consumption.

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We present a patient with a lytic lesion of the distal ulna for which imaging findings suggested an aneurysmal bone cyst. Diabetes mellitus (DM) is reported as being a risk factor associated with kidney cancer in Western countries. Altered regions were found at cytobands 1p31.3, 1q44, 2p23.1, 3p26.3, 3q22.3, 4q22.3, 4q35.2, 5q23.2, 8q22.3, 8q24.13, 9q21.3, 9q22.32, 10q11.21, 11p13, 12p12.1, 13q12.1, 16q12.2 and 18q21.31. Electrophoretic analysis of radioiodinated cell surface proteins immunoprecipitated with an anti-69-kDa osteopontin serum, demonstrates that the 69-kDa osteopontin is also present on the cell surface, but only its phosphorylated form (pp69) shows such cell surface association. We study synchronization properties of general uncoupled limit-cycle oscillators driven by common and independent Gaussian white noises. Marked differences in upper limits of normal were found for parameters related to the esophageal sphincters and TZ length. In the first study various parameters of forearm blood flow were measured in a group of 31 normal subjects. Among the 18 patients, hypertension was the most common underlying cause of renal failure.

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A genetic basis for the syndrome is supported by its occurrence in identical twins. A 73-year-old man presented with DeBakey type IIIa chronic aortic dissection. Altering CO2 during reperfusion of ischemic cardiomyocytes modifies mitochondrial oxidant injury. The expression of CK19 may be served as an available method to evaluate occult micrometastases in laryngeal squamous cell carcinoma. An unusual reactivity of sterically hindered o-quinones with an annelated dithiete ring towards coordination at a dithiolene site has been discovered.

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One patient had a postoperative ileus that resolved with nonoperative management. The Accuracy and Efficacy of the Dexcom G4 Platinum Continuous Glucose Monitoring System. We applied ttScreening to 383,998 CpG sites in association with maternal smoking, one of the leading factors for cancer risk. Information about cause of injury, which is available for fatal injuries, is rarely available for severe nonfatal injuries. The doppler echocardiography has emerged as an important noninvasive diagnostic tool, providing reliable data in the stages of diastolic function, as well as for systolic function. Investigations revealed grossly raised CRP with negative immunology screen. tenagophila cell-free haemolymph, especially from Taim strain, was responsible for significant increase in sporocyst mortality compared to B. The addition of concurrent cisplatin-based CT to RT significantly improves progression-free and overall survival for high-risk, early-stage patients who undergo radical hysterectomy and pelvic lymphadenectomy for carcinoma of the cervix. Nutritional status of alcoholics of different socioeconomic class. Therefore, in the future, consideration should be given to a metal-protein or masking agent-protein interaction using a model compound such as a chelate resin.

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Moreover, compound 8l could induce apoptosis in K562 cell lines through mitochondrial pathway. Hematoxylin-safranin-O-fast-green staining assays were used to observe cartilage nodules, and Pitx1 expression was examined by immunofluorescent microscopy. Ventilation with a high concentration of oxygen after abdomen deflation raises concerns of increased oxidative stress but has also been shown to exert beneficial effects on splanchnic ischemia/reperfusion. To address this issue, here we developed a photo-cross-linking mobic meloxicam dosage probe in which a cleavable linker of a diazobenzene moiety was employed to allow selective elution of cross-linked proteins by reducing agent-mediated cleavage. Glutamate stimulation of astrocytes was followed by an increase in the incidence of small, transient, inward currents in sniffer cells, reminiscent of postsynaptic quantal events observed at synapses. The development of modern nucleotide sequencing techniques and new biocomputational tools allow the possibility of studying the diversity and complexity of the microbiome in the whole gastrointestinal (GI) tract and overcome the limitations of culturing techniques. Differential surface labeling and internalization of glucagon by peripheral leukocytes. Rationalizing translation attenuation in the network architecture of the unfolded protein response. Participants represented varied backgrounds, ages, sexual orientations, exposure to risk behaviours, lifestyles, roles, and citizenship.

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An unusual local reaction to continuous subcutaneous infused terbutaline in unstable asthmatics. The data obtained post-QC is then examined using variance components analysis to quantify the amount of variance due to some of the factors in the experimental design. Ankyrin-B (AnkB) is required for targeting and stabilizing ion channels, exchangers, and pumps. Complete eversion of the urinary bladder: presentation, review, and algorithm for management. Standing hospital orders facilitated enrollment to the cardiac rehabilitation clinical trial, yet women failed to participate predominantly due to significant patient-oriented biopsychosocial barriers. This study compared and examined the effectiveness of salivary duct repositioning in decreasing the incidence of obstructive complications. Repeated surgery using patch grafts in this Hispanic population was also safe.

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Visual presentation of phobic stimuli: amygdala activation via an extrageniculostriate pathway?. A 65-year-old male presented with decreased vision in the left eye of 15-day duration after having undergone an uneventful cataract surgery 10 months back. The frequency of terminal duct lobular units (TDLUs) and occult neoplastic epithelial proliferation in grossly/clinically unremarkable nipples (GUNs) is not well investigated. In vitro kinase assays demonstrate that IKK-i phosphorylates I-TRAF in the parlodel dosage to stop lactation middle portion that associates with TRAF2. The patient is a 14-year-old boy with a large osteosarcoma tumor in the first sacral vertebral body, with extra skeletal extension. Removable partial dentures are also not preferred for its bulkiness and reduced esthetics.

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Strong mutual-coupling induced by the grating inside the ring leads to split resonances and accompanying large anomalous dispersion, thus providing a new approach to realizing fast light in the over-coupled region of the ring resonator. The 5-year program is the competency-based surgical education training (SET) program. In vivo study showed that DHA treatment decreased OC number, prevents bone loss, rescues bone microarchitecture and restores bone strength in LPS-induced bone-loss mouse model. Therapists using techniques to improve joint range of motion in clients with MPS should be aware that pterygia may include contractile tissue, nerves, and blood vessels and there may be underlying skeletal deformity or weakness in these areas. The aim of this study was to identify underlying mechanisms involved in HBx-mediated epigenetic modification. Nerve cell lines with stable properties are isolated from neuroblastomas, glioblastomas or pheochromocytomas by periodic cloning using defined culture media. Imipenem versus piperacillin/tazobactam for empiric treatment of neutropenic fever in adults. We further analyze the protein interaction predictions generated by the models, and find some interesting insights. One hundred and fourteen patients with esophageal carcinoma who underwent esophagogastrectomy from January 2006 to October 2007 in our department were studied.

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Arrest of transcription following anoxic exposure in a marine mollusc. We also describe the Reservoir Computing Toolbox that was used for these experiments, which implements all the types of Reservoir Computing and allows the easy simulation of a wide range of reservoir topologies for a number of benchmarks bactrim antibiotics uti . Neutrophil chemotaxis requires excitatory signals at the front and inhibitory signals at the back of cells, which regulate cell migration in a chemotactic gradient field. The development of specialized software permitted the analysis of the extent of colocalization between the two differentially labeled sets of cellular structures over time. STATISTICAL METHODS AND FINDINGS: Peer groups are developed by first calculating the multidimensional Euclidean distance between each of 133 VA medical centers based on 16 facility characteristics. The common channel of the Roux-en-Y is shortened to 5-7 ft of ileum.

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The 4-hydroxynonenal (4-HNE), ataxia-telangiectasia mutated kinase (ATM), phosphorylated histone H2AX (gammaH2AX), phosphatidylinositol-3 kinase (PI3K), Akt and superoxide dismutase (SOD) were assessed by western blot analysis. Garcinol, a polyisoprenylated benzophenone modulates multiple proinflammatory signaling cascades leading to the suppression of growth and survival of head and neck carcinoma. The differences in the serum levels of these nutritional factors may be associated with lamisil generic medication the differences in the risk of coronary heart disease and cancer between Finnish and Japanese populations. WSSV ORF403 is predicted to encode a protein of 641 amino acids, which contains a C3H2C2 RING structure. Trigeminal-facial nerve communication and its clinical application. However, little is known about the changes in amino acid metabolism in such patients. These inhibitory effects were reversed by alpha-flupenthixol (s.c.), suggesting a role for dopamine (DA) in the observed opiate-induced effect.

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Inhibition of angiogenesis is a main strategy for treating corneal neovascularization. In health care settings patient access to medicines is often less direct. The present study employed Affymetrix bovine expression microarrays to examine global gene expression patterns of SCNT and in vivo produced (AI) blastocysts as well as cotyledons from day-70 SCNT and AI pregnancies. The relation of chromosomal aberrations to parathyroid hormone, as well as calcium and phosphate serum concentrations, was assessed. Gabapentin Superadded to a Pre-Existent Regime Containing Amytriptyline for Chronic Sciatica. Low-density lipoprotein cholesterol and apoprotein olanzapine zyprexa 20 mg tablet B increased during therapy.

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