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Azenate (Azelastine)

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Azenate nasal spray is a fast-acting, efficacious and well-tolerated H1-receptor antagonist for the treatment of rhinitis. In addition it also has mast-cell stabilizing and anti-inflammatory properties, reducing the concentration of leukotrienes, kinins and platelet activating factor in vitro and in vivo, as well as inflammatory cell migration in rhinitis patients.

Other names for this medication:
Astepro, Azelast, Azelastine, Azenate, Duonase, Nazomac, Oculast, Optihist, Optivar

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Parlodel, Altace, Cordarone, Azulfidine, Cleocin, Aygestin, Ultram, Minocin, Albenza, Theolair

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Also known as: Azelastine


Azelastine nasal spray is used to help relieve symptoms (eg, stuffy or runny nose, itching, sneezing) of seasonal (short-term) or perennial (year-round) allergic rhinitis (hay fever), vasomotor rhinitis, or other upper respiratory allergies.

Azelastine is an antihistamine. It works by preventing the effects of a substance called histamine, which is produced by the body. Histamine can cause itching, sneezing, runny nose, and watery eyes.

This medicine is available only with your doctor's prescription.


Use Azenate nasal spray exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Before you use Azenate Nasal Spray for the first time, you will need to prime the bottle.

Remove the blue dust cover over the tip of the pump and the blue safety clip just under the "shoulders" of the pump.

Hold the bottle upright with 2 fingers on the shoulders of the spray pump unit and put your thumb on the bottom of the bottle. Press upward with your thumb and release for the pumping action. Repeat this until you see a fine mist To get a fine mist you must pump the spray fast and use firm pressure against the bottom of the bottle. If you see a stream of liquid, the pump is not working correctly and you may have nasal discomfort This should happen in 4 sprays or less.

Now your pump is primed and ready to use.

Using your Azenate Nasal Spray.

Blow your nose to clear your nostrils. Keep your head tilted downward toward your toes. Place the spray tip about ¼ inch to ½ inch into 1 nostril. Hold bottle upright and aim the spray tip toward the back of your nose Close your other nostril with a finger. Press the pump 1 time and sniff gently at the same time, keeping your head tilted forward and down Repeat in your other nostril If your healthcare provider tells you to use 2 sprays in each nostril, repeat Steps 2 through 4 above for the second spray in each nostril Breathe in gently, and do not tilt your head back after using Azenate Nasal Spray. This will help to keep the medicine from going into your throat When you finish using your Azenate Nasal Spray, wipe the spray tip with a clean tissue or cloth. Put the safety clip and dust cover back on the bottle.

Avoid getting this medicine in your eyes or mouth.

Do not allow a young child to use Azenate without help from an adult.

Call your doctor if your symptoms do not improve, or if they get worse.

Store this medicine in an upright position at room temperature. Do not freeze.

Throw away the medicine after you have used 200 sprays, even if there is still medicine left in the bottle.

Detailed Azenate dosage information


If you overdose Azenate and you don't feel good you should visit your doctor or health care provider immediately.


Store at a room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and sunlight. Keep in a tightly closed container. Throw away the after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Azenate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before using Azenate tell your doctor about all your medical conditions or allergies.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Using Azenate while you are breast-feeding may cause your breast milk to taste bitter. If you breast-feed while using this medicine, watch for signs that your baby is not nursing as well. Talk to your doctor about the best way to feed your baby.

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The stressful stimuli elicited a significant increase in LC neuronal activity for the entire 15 min stressor duration, whereas the behaviorally activating but nonstressful stimulus elicited no significant change in the activity of these neurons. After literature review, an increase in serum sodium concentration of no more than 8-10 mmol/litre in 24 hours is felt to be safe but can be exceeded with extreme caution if life-threatening symptoms do not resolve. Transpulmonary patch closure was used to repair the aortopulmonary window. The scope of these technologies varies from assessing a single cytosine-guanine locus to genome-wide distribution of DNA methylation. Sprague-Dawley male albino rats showed in a dose-response study a maximal drinking response to a 5 U/kg dose of SC insulin in a 2-hr test. Estradiol-17 beta induced rapid cellular hypertrophy, cytodifferentiation, tubular gland formation, organelle proliferation and secretory granule formation in different cells of the quail oviduct. A GAT-specific T-cell line restricted by a determinant carried by an HLA-DQ molecule. To evaluate the relation between serum and tissue levels of TGF-beta1 in psoriasis and their correlation with disease parameters.

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Markers of activated coagulation may be used to evaluate the coagulation status of cats with hypertrophic cardiomyopathy (HCM) in relation to left atrial size. However, there have been limitations to the interpretation of the tests because of paucity of details concerning penile innervation. Of these, the consumption of buckwheat noodles, but not other staple foods, is associated with IBS independent of carbohydrate or plant protein contents. Prospective studies are needed to explore this field and improve utility of donor and recipient genotype testing in managing immunosuppression therapy. We present here a global study of changes in mRNA abundance in response to hydrogen availability for a hydrogenotrophic methanogen. Cytochrome P450 oxidoreductase participates in nitric oxide consumption by rat brain. This study sought to develop a clinical model that identifies patients with and without high-risk coronary artery disease (CAD).

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