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Azithin (Azithromycin)
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Azithin

Azithin is in a group of drugs called macrolide antibiotics. Azithin fights bacteria in the body. Azithin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Azithin may also be used for purposes other than those listed in this medication guide.

Other names for this medication:
Azadose, Azalid, Azatril, Azicid, Azicine, Azidraw, Azihexal, Azilide, Azimex, Azimit, Azinil, Aziphar, Azitromicina, Azomac, Azromax, Ilozin, Koptin, Macrozit, Momicine, Novozitron, Ordipha, Orobiotic, Phagocin, Respazit, Ricilina, Sitrox, Tromic, Tromix, Unizitro, Vectocilina, Vinzam, Zibramax, Zithrin, Zithrocin, Zithrox, Zitromax, Zitrotek, Zymycin

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Also known as: Azithromycin

Description

Azithin (Azithin tablets and Azithin for oral suspension) contain the active ingredient azithromycin, a macrolide antibacterial drug, for oral administration. Azithin has the chemical name (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-[(2,6-dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl) oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one. Azithin is derived from erythromycin; however, it differs chemically from erythromycin in that a methyl-substituted nitrogen atom is incorporated into the lactone ring. Its molecular formula is C38H72N2O12, and its molecular weight is 749.00.

Azithin, as the dihydrate, is a white crystalline powder with a molecular formula of C38H72N2O12∙2H2O and a molecular weight of 785.0.

Azithin is supplied as tablets containing azithromycin dihydrate equivalent to either 250 mg or 500 mg azithromycin and the following inactive ingredients: dibasic calcium phosphate anhydrous, pregelatinized starch, sodium croscarmellose, magnesium stearate, sodium lauryl sulfate, hypromellose, lactose, titanium dioxide, triacetin, and D&C Red #30 aluminum lake.

Azithin for oral suspension is supplied in bottles containing azithromycin dihydrate powder equivalent to 300 mg, 600 mg, 900 mg, or 1200 mg azithromycin per bottle and the following inactive ingredients: sucrose; sodium phosphate, tribasic, anhydrous; hydroxypropyl cellulose; xanthan gum; FD&C Red #40; and spray dried artificial cherry, creme de vanilla, and banana flavors. After constitution, each 5 mL of suspension contains 100 mg or 200 mg of azithromycin.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Azithin Z-Pak oral is taken by mouth. This medicine injection is given as an infusion into a vein, usually for 2 days before you switch to this medicine oral. A healthcare provider will give you this injection.

You may take Azithin Z-Pak oral with or without food.

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Use Azithin Z-Pak for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Azithin Z-Pak will not treat a viral infection such as the flu or a common cold.

Store at room temperature away from moisture and heat. Throw away any unused liquid medicine after 10 days.

Detailed Azithin dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not refrigerate or freeze the Zmax® extended-release oral suspension. After water has been added to the powder, use the dose within 12 hours and throw away any unused liquid after your dose.

You may store the Azithin® oral liquid at room temperature or in the refrigerator. Do not freeze the bottle. Do not keep the oral liquid for more than 10 days. Throw away any unused liquid after all doses are completed.

Detailed Azithin dosage information

Side effects

The most common side effects associated with Azithin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of azithromycin in the elderly. However, elderly patients are more likely to have heart rhythm problems (eg, torsades de pointes) which may require caution in patients receiving azithromycin.

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No significant differences were observed between IgG and Fab antivenoms concerning neutralization of hemorrhagic and edema-forming activities, whereas IgG antivenom was slightly more effective in neutralizing myotoxic activity in experiments involving independent injection of venom and antivenom. We predicted three symptom domains would withstand conservative adjustments in their relationship to TLEs: posttraumatic stress disorder (PTSD), borderline personality disorder (BPD), and attenuated positive psychotic symptoms (APPS). No disease-modifying treatment exists for the fatal neurodegenerative polyglutamine disease known both as Machado-Joseph disease and spinocerebellar ataxia type 3. This finding is at odds with the claim that negative words could capture spatial or object-based mechanisms of visual attention. The experimental results indicated 1 mmoL (81.4 microg) prilosec generic omeprazole nano ZnO could completely inhibit the growth of 10(7) cfu/mL bacterial cells in liquid Luria-Betrani medium. Cost-Effectiveness Analysis of Secukinumab Compared to Ustekinumab In The Treatment of Moderate to Severe Plaque Psoriasis In The Czech Republic.

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In case of local risk of recurrence, adjuvant radiotherapy decreases the risk of biochemical recurrence but does not improve the overall survival. Patients receiving IVIg replacement therapy within 3 months of the diagnosis and for at least 4 years between 1982 and 1997 were included. It binds in vivo to the adaptor proteins Nck and Grb2, to the cytoplasmic protein-tyrosine kinase Fyn and to the small Rho-like GTPase Cdc42, which is required for formation of filopodia in fibroblasts and macrophages. The stoichiometric hybridization, however, puts an intrinsic limitation on detection sensitivity, because one target molecule converts only one beacon molecule to its fluorescent form. It was demonstrated that the intracarpal pressure is minimum when the wrist is in neutral position. Although a solid, the highly flexible characteristic of the developed TIMs enables a perfect ability to replicate the texture of a rough surface, which may greatly enhance thermal transfer between adjacent surfaces. Results from the present study demonstrated that statin administration in early life to dams fed on a HFD had a significant effect on their female offspring in terms of reduction in cardiovascular risk factors. Such augmented alpha-adrenergic coronary constriction is observed during exercise and coronary interventions, and it is powerful enough to induce myocardial ischemia and limit myocardial function.

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