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Azolam (Alprazolam)
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Azolam

Azolam is used to treat anxiety and panic disorders. It belongs to a class of medications called benzodiazepines which act on the brain and nerves (central nervous system) to produce a calming effect. It works by enhancing the effects of a certain natural chemical in the body (GABA). Azolam is mostly used to treat anxiety disorders, panic disorders, and nausea due to chemotherapy. Azolam may also be indicated for the treatment of generalized anxiety disorder, as well as for the treatment of anxiety conditions with co-morbid depression. The FDA label advises that the physician should periodically reassess the usefulness of the drug.

Other names for this medication:
Actirax, Albiz, Alparazole, Alpkair, Alpramax, Alprastan, Alprocontin, Alprosym, Alwe, Alzac, Alzomax, Alzotime, Ambutech, Andep, Anxilam, Anxitab, Anxorel, Anzocalm, Apsolam, Azicalm, Azoslip, Depwell, Destres, Fledore, Nitril, Optizole, Pacyl, Pifzot, Pralam, Richpram, Riolam, Romipraz, Somnia, Synozolam, Tenolam, Visram, Zolam, Zolark, Zolorest, Zolyde, Zopam

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Arcoxia, Medrol, Glucophage, Fasigyn, Dramamine, Remeron, Zetia, Exelon

Also known as: Alprazolam

Description

Azolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Azolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Azolam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Azolam or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Azolam. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Azolam. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention if you think you have used too much of this medicine. An overdose of Azolam XR can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, fainting, and coma.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Azolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not drink alcohol while taking Azolam XR. This medication can increase the effects of alcohol. Azolam XR can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.

Grapefruit and grapefruit juice may interact with Azolam XR and lead to potentially dangerous effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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The Past and Future Trends of Heat Stress Based On Wet Bulb Globe Temperature Index in Outdoor Environment of Tehran City, Iran. Cellular accumulation of Gb(3) reduces HIV susceptibility in vitro, whereas lack of Gb(3) promotes infection, suggesting that Gb(3) expression could be a novel risk factor for HIV susceptibility. To synthesize the evidence about the association of thiazolidinedione therapy with advanced liver fibrosis in NASH. Mass spectrometry profiling of oxylipins, endocannabinoids, and N-acylethanolamines in human lung lavage fluids reveals responsiveness of prostaglandin E2 and associated lipid metabolites to biodiesel exhaust exposure. Semi-structured focus groups were conducted with adult critical care nurses from four intensive care units, two in Australia and two in New Zealand. The changing epidemiology of hepatitis C virus infection in Europe. Transcellular transport of CCL2 across brain microvascular endothelial cells. Scrapie transmission in Britain: a recipe for a mathematical model. The signal representation used can be generalized to handle problems of line fitting and of straight edge detection. A 69-year-old woman presented a dropped head, caused by severe neck extensor weakness that had started two years before.

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Genetic polymorphisms and recurrent spontaneous abortions: an overview of current knowledge. To assess the knowledge and attitude regarding Ebola virus disease (EVD) among medical students of Rawalpindi. Nonalcoholic fatty liver disease (NAFLD) is becoming a worldwide health crisis. To examine demographic and socioeconomic characteristics of parents and children in families not participating in preventive child health examinations at the general practitioner in a society with free and easy access to healthcare. One of the mechanisms by which social relationships may alter health status is through altering patterns of neuroendocrine or hemodynamic responding to ongoing activity. The occurrence and distribution of four opioid peptides (methionine-enkephalin /met-enk/, leucine-enkephalin /leu-enk/, dynorphin-A /dyn-A/, dynorphin-B /dyn-B/) were studied and compared in the subregions and layers of the hippocampi of four rodent species (rat, mouse, hamster and guinea-pig) by means of pre-embedding immunocytochemistry in order to reveal species-specific morphological characteristics. Moreover, this work suggests that the value of c-MET tyrosine kinase inhibitors in the treatment of patients with CRC lung metastases should be assessed in clinical trials.

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Study on spatial distribution of crop residue burning and PM2.5 change in China. The LAA stroke patients were divided into clinical subgroups according to the presence of microembolic signals, severity of neurologic deficits at admission, and the degree of vascular stenosis. Here, we report that ARF associates with COMMD1 and promotes Lys(63)-mediated polyubiquitination of COMMD1 in a p53-independent manner. Furthermore, E/rG inhibited the growth of A549 cells by cytotoxic effects that blocked tumor proliferation, and the immunotoxin-induced cell death may be mediated by autophagy. Low-dimensional attractor for neural activity from local field potentials in optogenetic mice. In contrast, Candida morphology was only affected by supernatant containing HSLs.

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Surgical intervention may be indicated in shoeproblems, for esthetic reasons or, especially in duplication of the metatarsales, because of secondary deviation of the toes and therefore shoeproblems or plantar callosities. Cho/NAA, NAA/Cr, and Cho/Cr ratios were identified in seven pre-determined sites without tumor involvement. To assess whether contractile reserve during dobutamine stress echocardiography (DSE) can predict left ventricular functional recovery in patients with peripartum cardiomyopathy and to assess myocardial fibrosis by magnetic resonance imaging (MRI) in these patients. Endoscopic aspiration of brain abscess appears to be a safe and effective alternative method of treatment. Two patients were surgically treated, one for unsuccessful dilatation, and the other for the complication that occurred during dilatation. Tumors develop resistance to chemotherapeutic through a variety of mechanisms, with tumor microenvironment (TM) serving pivotal roles. In order to acquire flexible tracks with excellent conductivity at room temperature on paper and PET, nano silver emulsion of 2 percent silver content was prepared through liquid phase chemical reduction, and then the concentration of silver was improved to 17 percent by centrifuging at high speed. Magnetic nanoparticles are gaining great roles in biomedical applications as targeted drug delivery agents or targeted imaging contrast agents. The project has successfully developed a synthetic aperture sonar system for producing high resolution images of the sea floor and that has been tested during a series of sea trials in May 1993 off the south coast of France.

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Major progress in deciphering the role of the E3 ligase, ITCH, in animal physiology has come from the generation and identification of Itch loss-of-function mutant mice (itchy). Stimulation of cell cycle entry by growth factor signaling leads to activation of cyclin dependent kinases. Telomere length assessment: biomarker of chronic oxidative stress?. On each of the 264 radiographs, 4 independent examiners measured the central depth (CD) of 1 carious lesion per tooth both on the unchanged radiographic image and after use of the filter. Simulations of the application of the results presented to image restoration are finally provided. We present six experiments that examine cumulative structural priming effects (i.e., structural priming effects that accumulate across many utterances).

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Several factors associated with coagulation and/or fibrinolysis have been associated with arterial occlusive disease, but the role of F2 20210A and F5 1691A for arterial occlusive disease remains unclear. Epilepsy with myoclonic atonic seizures and chronic cerebellar symptoms associated with antibodies against glutamate receptors N2B and D2 in serum and cerebrospinal fluid. Multisensor approach to walking distance estimation with foot inertial sensing. The complexity of such reusable accessory devices is reviewed, and the critical aspects of cleaning, sterilization, and quality assurance are discussed. Evolution during acrometastasis of gastric cancer is the same one as in the other acrometastases. Instead, at least three regulatory proteins independently control the expression of gene products involved in nitrogen metabolism in response to nutrient availability.

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Enhancement of docosahexaenoic acid production by low-energy ion implantation coupled with screening method based on Sudan black B staining in Schizochytrium sp. Lipid interactions and angle of approach to the HIV-1 viral membrane of broadly neutralizing antibody 10E8: Insights for vaccine and therapeutic design. 99mTc HMPAO labeled leukocyte scintigraphy is useful, particularly in children, because less peripheral blood volume is required for labeling. Atorvastatin has neuroprotective effects, and there is some evidence that nitric oxide is involved in atorvastatin effects. Inhibition of NS3-4A protease activity has been validated as an antiviral target in clinical studies of inhibitors of the enzyme. We investigated 33 different ring chromosomes in patients with phenotypic abnormalities by array based comparative genomic hybridisation (CGH) and fluorescence in situ hybridisation (FISH). Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line. The literature shows that radiotherapy and small-molecule inhibitors may be promising alternatives. A simple feasible intervention in community pharmacies, incorporating daily reminders via Inhaler Technique Labels on inhalers, can lead to improvement in inhaler technique and asthma outcomes.

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