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Azona (Ziprasidone)

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Azona helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life. Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal.

Other names for this medication:
Azona, Ziprasidone, Zipsydon

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Also known as: Ziprasidone


Ziprasidone injection is used to treat agitation that occurs with schizophrenia. It should not be used to treat behavioral problems in elderly patients who have dementia. Ziprasidone works by changing some of the chemicals in the brain that cause schizophrenia.

This medicine is to be given only by or under the direct supervision of your doctor.


It is recommended to take Generic Azona at the same time twice a day. Generic Azona should be taken with food. Do not crush, chew, or break the tablet. Swallow it whole with water. If you want to achieve most effective results do not stop taking Generic Azona suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include cause excessive sleepiness, slurred speech, high blood pressure, shaking, tremors, or anxiety.

While you are taking Azona, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medicine.

Azona may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Dizziness or severe drowsiness can cause falls, fractures, or other injuries.

Avoid drinking alcohol. Dangerous side effects could occur.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Azona are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Azona if you are allergic to ziprasidone, or if you have:

a heart rhythm disorder; a personal or family history of long QT syndrome; uncontrolled or untreated heart failure; or if you have recently had a heart attack.

Azona is not approved for use in psychotic conditions related to dementia. Ziprasidone may increase the risk of death in older adults with dementia-related psychosis.

Azona should never be taken together with any of the following drugs, or a life-threatening heart rhythm disorder could occur:

anagrelide; methadone; tacrolimus; certain anti-nausea medicines including dolasetron, droperidol, or ondansetron; the antibiotics azithromycin, clarithromycin, erythromycin, levofloxacin, moxifloxacin, and pentamidine; certain cancer medicines such as arsenic trioxide and vandetanib; the antidepressants citalopram, escitalopram; anti-malaria medications including chloroquine, halofantrine, mefloquine; the following heart rhythm medicines - amiodarone, disopyramide, dofetilide, dronedarone, flecainide, ibutilide, quinidine, sotalol; or certain anti-psychotics such as chlorpromazine, haloperidol, mesoridazine, pimozide, and thioridazine.

This list is not complete and there may be other drugs that should not be taken at the same time as Azona. Tell your doctor about all medicines you use.

To make sure Azona is safe for you, tell your doctor if you have ever had:

any heart problems; a heart attack or stroke; a bone marrow or blood cell disorder; breast cancer; low blood levels of potassium or magnesium; diabetes (ziprasidone may raise your blood sugar); seizures or epilepsy; suicidal thoughts; Alzheimer's disease; trouble swallowing; liver disease; or kidney disease.

Tell your doctor if you are pregnant or plan to become pregnant during treatment.

Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking Azona, do not stop taking it without your doctor's advice.

It is not known whether ziprasidone passes into breast milk or if it could harm a nursing baby. Talk to your doctor about Azona if you are planning to breastfeed.

Older adults may be more sensitive to the effects of this medicine.

Azona is not approved for use by anyone younger than 18 years old.

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