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Benzolam (Alprazolam)

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Benzolam is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

Other names for this medication:
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Lodine, Provera, Bactrim, Exelon, Clozaril

Also known as: Alprazolam


Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Benzolam. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Benzolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

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Molecular modeling studies of the cross-reactive drugs suggest that, depending on the monoclonal antibody, both steric and electronic features govern antibody binding. Although recognized for more than 100 years, its incidence has been underestimated in the past due to the lack of accurate diagnostic techniques. Communication: epistructural thermodynamics of soluble proteins. PRKCD is expressed at low level in human corticotroph adenomas and controls cell cycle in vitro. The key structural features of promoter opening are summarized here. Eighteen psychosocial work factors were studied: low decision latitude (skill discretion and decision authority), high psychological demands, job strain, low social support, iso-strain, physical violence, sexual harassment, bullying, discrimination, work-family imbalance, long working hours, high effort, job insecurity, low job promotion, low reward and effort-reward imbalance. Semi-domesticated crops provide excellent opportunities to examine the interplay of natural and anthropogenic influences on plant evolution. Cytotoxic MD45 T cells grafted with the scFv763.74-gammaR receptor bind specifically to high molecular weight-melanoma associated antigen-positive melanoma cells and lyse melanoma cells in a human leukocyte antigen class I independent fashion.

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This paper reviews the role of SBRT for liver metastases, hepatocellular carcinoma and cholangiocarcinoma, paying special attention to patient eligibility and treatment outcomes regarding local control, toxicity and quality of life. The nanowire is composed of CuS nanoparticles with hexagonal structure. Identification of differentially expressed microRNAs between Bacillus thuringiensis Cry1Ab-resistant and -susceptible strains of Ostrinia furnacalis. In conclusion, short-term feeding of diets resembling human diets (Mediterranean diet high in monounsaturated fat, diet high in saturated fat, or diet high in polyunsaturated fat) can affect tissue levels of endocannabinoids and N-acylethanolamines. The in vitro aggregometric response of platelets to ADP, collagen, thrombin, ristocetin was present, but shape change was absent. Between 2004 and 2014, a retrospective review at a level I trauma center identified patients with unilateral or bilateral dislocated facet(s). Preoperative plasma endoglin improves the accuracy for prediction of pelvic lymph node metastasis in patients treated with radical prostatectomy for clinically localized prostate cancer by a statistically and clinically significant margin. Persistence of WSSV DNA in pond soil samples after various time intervals was determined.

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The impact of ultrasound analysis onto clean margin rates was evaluated. The parameters, which have been found to be significant prognostic factors, were incorporated into the final risk model, based on a scoring system. This decline reflects better survival after NHL diagnosis, likely from improved therapies, because the decline in NHL incidence occurred later. Indian hedgehog promotes the migration of rat activated pancreatic stellate cells by increasing membrane type-1 matrix metalloproteinase on the plasma membrane. In eight hemiplegic patients the net joint torque of passive muscle stretch was measured as a function of ankle-angle by a dynamometer, at both sides. Giant mediastinal teratoma in an infant successfully treated by emergency surgery. We evaluated whether the dual specificity phosphatase MAP kinase phosphatase (MKP)-3, which is highly expressed in the lung and specifically dephosphorylates ERK, was increased after exposure to asbestos. Furthermore, we investigated public preferences on the practical implementation: either the patient seeks a donor or the donor registers for donation at an independent institute.

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In addition, we found that tadpole-transporting frogs were attracted to novel sites that contained high concentrations of conspecific olfactory tadpole cues. The use of the intraaortic balloon pump (IABP) in patients undergoing coronary artery bypass grafting has been traditionally associated with a high complication rate and adverse outcomes. By analyzing relevant domestic and international literature and their own long-standing experience, the authors discuss the problem of urinary incontinence in the context of estrogen deficiency. Real-time compensation of the refractive index of air in distance measurement. Finally, we introduce our own mathematical modeling views based on how the developmental dynamics of individual lymphoid cells combine to sustain allelic exclusion.

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13C and 19F solid-state NMR and X-ray crystallographic study of halogen-bonded frameworks featuring nitrogen-containing heterocycles. A major drawback in the analysis of HAAs in foods is their very low level of concentration (0.1 50 ng g-1) as well as matrix interferences. An additional prospective longitudinal study should be carried out to support these findings. Report of the Committee on Professional Education (Proposed Report on the Educational and Experience Qualifications of Laboratory Workers). Colonoscopy is useful in the diagnosis, treatment of colorectal diseases, and for colorectal cancer screening program.

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Although public health guidelines have implications for resource allocation, these issues were not explicitly considered in previous WHO pandemic preparedness and response guidance. A 58-year-old man presented with subarachnoid hemorrhage (SAH) resulting from a secondary perimedullary arteriovenous fistula (AVF) induced by a glass stab injury to his right posterior neck. aureus to fibroblasts and epithelial cells was significantly enhanced by addition of Eap, presumably due to its affinity both for plasma proteins on the cells and for the bacteria. Prediction of mutations in H3N2 hemagglutinins of influenza A virus from North America based on different datasets. Proximal myotonic myopathy (PROMM) is a multisystem disorder that may mimic myotonic dystrophy (MD). This review continues a series of publications on the roles of different amino acids in defining the phenomenon of protein intrinsic disorder and represents serine, which is the third most disorder-promoting residue. An additional questionnaire explored demographic and preoperative factors like onset and duration of symptoms, preoperative treatment and smoking habits. Moreover, we identified vitellogenin A (Vtg A) and Vtg B as estrogen-responsive genes expressed in the female S. Four research centers interviewed 150 adult inpatients or outpatients, and one research center interviewed 140 patients.

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Sustained routine use of Hib vaccine will contribute to the prevention of childhood morbidity and mortality. We compared the accuracy of traditional methods versus using frozen stocks for preparing Acinetobacter baumannii inocula for infection in mice. The secreted glycoproteins, Slit1-3, are classic axon guidance molecules that act as repulsive cues through their well characterised receptors Robo1-2 to allow precise axon pathfinding and neuronal migration. The aim of this study was to compare the flank approach and the anterior sub-mesocolic access carrying out left laparoscopic adrenalectomy (LA). Molecular predictors of their efficacy are crucial for further development. In mammalian cells, efforts to understand how autophagosomes form have been focused on the role of Rab proteins in autophagy. Adhesion of human neutrophils in the presence of whole serum was significantly inhibited by 50-100nM dasatinib, which corresponds to the reported serum concentrations in dasatinib-treated patients.

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Development of regenerative therapeutic strategies to reverse the progression of advanced heart failure is one of the most urgent clinical needs of this century. Evidence from our lab has demonstrated that improper activation of the innate immune system can reduce embryo implantation, thus leading to infertility. We describe here a series of N-(quinolin-8-yl)benzenesulfonamides capable of suppressing the NFkappaB pathway identified from two high-throughput screens run at two centers of the NIH Molecular Libraries Initiative. Lactic dehydrogenase isozymes in the extraocular muscles of rabbits. Micromachined silicon acoustic delay lines for ultrasound applications. Paclitaxel plus bevacizumab in patients with chemoresistant relapsed small cell lung cancer as salvage treatment: a phase II multicenter study of the Hellenic Oncology Research Group. The challenge for the clinical genetic laboratory is to keep pace with this information explosion to provide state-of-the-art genetic testing and to ensure that the genetic test results are used in a morally, ethically, and socially responsible way. The patient responded positively to treatment with topical tacrolimus, suggesting that abnormalities in the immunoregulatory mechanism may be involved in the pathogenesis of ILC. To understand the molecular basis of tumorigenicity, we characterized nontumorigenic CGL1 and tumorigenic CGL4 cell lines, both of which were originated from a common ancestral HeLa-human diploid fibroblast hybrid cell clone and retained a malignant state except tumorigenicity. 16S rRNA sequencing is a key methodology in identifying these bacterial populations that has recently transitioned from use primarily in research to having increased utility in clinical settings.

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Partial resection of the fractured first and second ribs was performed on all calves. Development of an alkali chloride vapour-generating apparatus for calibration of ultraviolet absorption measurements. The average lead intake was calculated to be 15 micrograms/person per week, which is very low, whereas the intake of cadmium and mercury was estimated to be very high, on average 1004 micrograms/person per week for cadmium and 846 for mercury, thereby significantly exceeding limits established by FAO/WHO. Our case highlights the underappreciated thrombotic risks of tranexamic acid (TXA) use in non-cardiac surgery and emphasizes the need to elucidate these risks with appropriate clinical trials. Furthermore, no cell cycle-dependent changes in Nek3 activity could be detected, and no effects upon cell cycle progression could be observed upon antibody microinjection or overexpression of either wild-type or catalytically inactive Nek3. Carbon dynamics on agricultural land reverting to woody land in Ontario, Canada. Third generation photosensitizers (PSs) are characterized by improved targeting to the diseased tissue and reduced systemic side effects. We determined that elevated plasma aldosterone concentration is an independent risk factor for ED. Vaginal Mesh in Pelvic Reconstructive Surgery: Controversies, Current Use, and Complications.

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The attitudes and practice of patients with eczema managed at a pediatric dermatology clinic were evaluated, using children with non-eczematous skin diseases as controls. Left ventricular systolic synchronicity was impaired in hypertensive patients with LVH. Unilateral cochlear damage has profound effects on the central auditory pathways in the brain. Mutation screening was performed using both the polymerase chain reaction-based amplification refractory mutation system and a commercial APC kit. Postreconstruction range of motion in AR, FE, and LB showed no significant differences between the four fixation constructs in the stable specimens. We propose a new technique for security verification of personal documents and other forms of personal identifications such as ID cards, passports, or credit cards. To evaluate genes involved in androgen receptor (AR) signaling as candidate genes for polycystic ovary syndrome (PCOS). Instead, the possible genetic links were found in women with positive family history of mental illness and menstrual irregularity, suggesting these could be identifying risk markers for women. Identifying the limits of these policies highlights the importance of considering alternative strategies, such as encouraging more independently funded esearch, in order to maintain the integrity of science.

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Phosphoregulation of Tau modulates inhibition of kinesin-1 motility. A negative shift was observed from (11)B and (29)Si NMR spectra. The size distribution of metastatic tumors and its time evolution are traditionally described by integrodifferential equations and stochastic models. Drug dependence is a recognized medical condition and therefore, right to health applies in the same way to drug dependence as it does to any other health condition. Despite a large number of studies on the mechanical unfolding of proteins, there are still relatively few successful attempts to refold proteins in the presence of a stretching force. Our aim was to determine whether dual-isotope parathyroid scintigraphy is useful in identifying thyroid cancer.

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Triple angiokinase inhibitors, which inhibit VEGF, PDGF and FGF, have potential to improve the therapeutic outcomes for patients with NSCLC. Moreover, we have used the variation in the accessory gland proteins to assess the extent of divergence between the species and to infer their population structure. Effects of polymerized oestrogens on the ventral prostate in rats. Mapping of discontinuous conformational epitopes by amide hydrogen/deuterium exchange mass spectrometry and computational docking. Sexual and Romantic Experiences of Transgender Youth Before Gender-Affirmative Treatment. Future research on MHFA should examine changes in MHL pre-post training and the extent to which perceived increases in MHL confidence among trainees translate into action. Models with the main effects presented using linear terms combined with various additional terms were estimated. MMAuria secondary to B(12) deficiency is quite common at Luliang district, suggesting B(12) deficiency is involved in the development of NTDs in the specific population. These deviations can be optimized by appropriate tuning of gains (i.e. Similarly, low-frequency and high-frequency power increased within the first 5 minutes compared with baseline.

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To screen or not to screen mothers of preterm infants for extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-E). This study reviews IOM modalities and documents practice patterns of spine surgeons at our single-center tertiary hospital about their use of various IOM modalities on 23 spinal procedures. Factors influencing this phenomenon and strategies that can be adopted to minimize the instability are discussed. This first clinical application suggests that controlled graft rewarming after cold storage is a feasible and safe method in clinical praxis and cost of amiodarone without insurance might become an adjunct in organ preservation. Is nihilism in the treatment of atheroembolic disease at an end?. We undertook the Biomarkers of Lupus Disease study to test withdrawal of immunosuppressants as a novel approach to rendering SLE trials interpretable. Furthermore, we introduce a correction of MSI data for variable slice thickness applicable to all MSI techniques.

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Selective small molecule targeting of phosphoinositide 3-kinase (PI3-kinase) gamma catalytic activity is a target of interest for anti-inflammatory pharmaceutical development. The aim of this study was to compare the safety and efficacy profile of chlorpromazine and olanzapine, as add-on to lithium, in patients with a first episode of psychotic mania, expecting better safety profile and adherence to olanzapine but similar efficacy for both treatments. The diagnosis of FAP was established on the mutation of the TTR gene detected by direct sequencing. This method identified functional clusters that were significantly different between the amnestic mild cognitively impaired (aMCI) and age-matched cognitively normal (CN) subjects. We discuss several counter-intuitive findings that have been reported in real life analyses, and we present calculations that may expand the understanding of these associations. The gap junction is important in the propagation of dilation/constriction signals along vessels for coordinated behavior in control of vascular tone. The at-risk children tended to show delayed P1 and P2 peaks for standard stimuli. Atomoxetine was well tolerated in most individuals, the two more common adverse events reported were gastro-intestinal disorders and decreased appetite. The frequency-to-distance mapping is digitally realized with equivalent references in data domain.

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Serum progesterone appeared to be the single most specific biomarker for distinguishing viable from nonviable pregnancies. Men with low testosterone levels caused by androgen deprivation therapy have worse grip strength, dexterity, 15D quality of life questionnaire scores, and depressive symptoms than age-matched men who have not received androgen deprivation therapy. This study characterizes the expression of human proacrosin in bacteria and assesses zona pellucida binding activity. Intraocular pressure after intravitreal injections should also be monitored long term after the procedure. Our analyses indicate that bifunctional RNAs may be involved in human embryonic development and can be functional in diverse tissues. A gastric digestion model that can be applied to prescreen peptides and reduce costs in the peptide microarray is also described in this chapter. (2) Which radiation strategies (dose, timing, fractionation, stereotactic radiation, brachytherapy, chemotherapy) improve outcomes compared to standard external beam radiation therapy in the initial management of low grade gliomas in adults?. A mechanism of catalysed annealing of gRNA/pre-mRNA by the MRP1/MRP2 complex is proposed. Caspase pathway activation and the expression of autophagy-related genes were examined using Western blot.

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