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Betrol (Glibenclamide)

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Betrol belongs to the class of drugs known as sulfonylureas. It lowers blood sugar by causing the release of your body's natural insulin. Betrol is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. It may also be used with other diabetes medications..

Other names for this medication:
Benclamet, Benformin, Codica, Diolin, Duotrol, Eumet, Glibact, Glibet, Glibson, Glifil, Glime, Glitrac, Glucored, Glucosil, Glucotrac, Glutowin, Glybenclamide, Glybid, Glybovin, Glycurub, Glymep, Iscept, Melitus, Metclam, Symet

Similar Products:
Dilantin, Atarax, Artane, Paxil, Urispas, Zyloprim, Tenormin, Zebeta, Provera

Also known as: Glibenclamide


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Usual Adult Dose for Diabetes Type 2:

Standard Betrol: -Initial dose: 2.5 mg to 5 mg orally once a day -Dose titration: Increase in increments of no more than 2.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 1.25 to 20 mg orally as a single dose or in divided doses -Maximum dose: 20 mg/day Micronized Betrol: -Initial dose: 1.5 mg to 3 mg orally once a day -Dose titration: Increase in increments of no more than 1.5 mg at weekly intervals based upon blood glucose response -Maintenance dose: 0.75 to 12 mg orally as a single dose or in divided doses -Maximum dose: 12 mg/day Comments: -Administer with breakfast or the first main meal of the day -Lower initial doses may be used in patients who are sensitive to hypoglycemic drugs -Once a day therapy is generally satisfactory, however, some patients may have a more satisfactory response with twice-a-day dosing, especially those receiving higher doses. TRANSFER FROM OTHER HYPOGLYCEMIC THERAPY: -Oral Antidiabetic Therapy: No exact dosage relationships exists between standard Betrol, micronized Betrol, or other oral hypoglycemic agents; when transferring patients from other oral hypoglycemic therapy, the maximum starting doses should be observed. -Insulin: --If the insulin dose is less than 20 units per day substitute 2.5 to 5 mg (standard) OR 1.5 to 3 mg (micronized) orally once a day. --If the insulin dose is between 20 and 40 units per day, substitute 5 mg (standard) OR 3 mg (micronized) orally once a day. --If the insulin dose is more than 40 units per day; transition the patient by concomitantly decreasing insulin by 50% and starting Betrol at 5 mg (standard) OR 3 mg (micronized) orally once a day; as insulin is progressively withdrawn, titrate in increments of 1.25 to 2.5 mg (standard) OR 0.75 to 1.5 mg (micronized) orally once a day every 2 to 10 days. Use: As an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.

Usual Geriatric Dose for Diabetes Type 2:

Initial dose: 1.25 to 2.5 mg (standard) orally or 0.75 to 1.5 mg (micronized) orally once a day.

Detailed Betrol dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Side effects

The most common side effects associated with Betrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of Betrol in the pediatric population. Safety and efficacy have not been established.

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Analysis of development of morphofunctional interconnections between CART- and AGRP-ergic neurons with dopaminergic structures in ontogenesis of mammals. Deaths from stomach cancer were significantly increased during 1965-9 but not over the entire follow up period (1950-80). Polycomb group protein Bmi1 is required for growth of RAF driven non-small-cell lung cancer. TGF-beta(1) is secreted in an inactive complex with latency-associated amethopterin peptide (LAP). To study the brain basis of such multi-stable percepts, we superimposed rapidly changing dynamic noise as regional tags to the Rubin vase-face figure and followed the corresponding tag-related cortical signals with magnetoencephalography.

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