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Biaxsig (Roxithromycin)

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Biaxsig is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Biaxsig is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring.

Other names for this medication:
Acevor, Aristomycin, Asmetic, Azuril, Bazuctril, Biaxsig, Biostatik, Cadithro, Claramid, Crolix, Delos, Dorolid, Elrox, Floxid, Infectoroxit, Klomicina, Macrolid, Macrosil, Monobac, Nirox, Odonticina, Overal, Pedilid, Ramivan, Remora, Ritosin, Rokilide, Rokithrid, Roksimin, Rolexit, Rolicyn, Rolid, Romac, Rotramin, Roxithromycin, Roxithromycine, Roxithromycinum, Roxitromicina, Rulid

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Also known as: Roxithromycin


Each Biaxsig tablet contains either 150mg or 300mg of the active ingredient roxithromycin. Each tablet also contains: hydroxypropylcellulose, poloxamer, povidone, colloidal anhydrous silica, magnesium stearate (470), purified talc (553), maize starch, hypromellose, anhydrous glucose, titanium dioxide (171), propylene glycol (1520). Biaxsig does not contain gluten, sucrose, lactose, tartrazine or any other azo dyes.


Biaxsig is typically prescribed for a period of 7 to 14 days and patients should take the medication for as long as it has been prescribed to prevent the infection from returning even if they become asymptomatic. Patients should not however, take doses larger than has been prescribed as this can result in an overdose. Overdosing requires immediate medical intervention and may present with symptoms which include abdominal pain, nausea, diarrhea, vomiting, and a general and prolonged feeling of illness.


If you overdose Generic Biaxsig and you don't feel good you should visit your doctor or health care provider immediately.


Keep the tablets in the foil until it is time to take them.

Keep the tablets/in a cool dry place where the temperature stays below 30 degrees C.

Do not store Biaxsig or any other medicine in the bathroom or near a sink.

Do not leave it in the car on hot days or on window sills.

Heat and dampness can destroy some medicines.

Keep it where children cannot reach it.

A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.

Side effects

The most common side effects associated with Biaxsig are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


The safety of roxithromycin has not been demonstrated in patients with impaired hepatic or renal function. Caution should be exercised if roxithromycin is administered to patients with impaired hepatic or renal function. If administered to patients with severe impaired hepatic function (eg. hepatic cirrhosis with jaundice and/or ascites), consideration should be given to reducing the daily dosage to half the usual dosage.

Prolonged or repeated use of antibiotics including roxithromycin may result in superinfection by resistant organisms. In the event of superinfection, roxithromycin should be discontinued and appropriate therapy instituted.

When indicated, incision, drainage or other appropriate surgical procedures should be performed in conjunction with antibiotic therapy.

Antibiotic associated pseudomembranous colitis has been reported with many antibiotics. A toxin produced by Clostridium difficile appears to be the primary cause. The severity of the colitis may range from mild to life threatening. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). Mild cases usually respond to drug discontinuation alone. However, in moderate to severe cases, appropriate therapy with a suitable oral antibacterial agent effective against Clostridium difficile should be considered. Fluids, electrolytes and protein replacement therapy should be provided when indicated.

Roxithromycin, like erythromycin, has been shown in vitro to elicit a concentration - dependent lengthening in cardiac action potential duration. Such an effect is manifested only at supra – therapeutic concentrations. Accordingly, the recommended doses should not be exceeded. In certain conditions macrolides, including roxithromycin, have the potential to prolong the QT interval. Therefore roxithromycin should be used with caution in patients with congenital prolongation of the QT interval, with ongoing proarrhythmic conditions (ie uncorrected hypokalemia or hypomagnesaemia, clinically significant bradycardia), and in patients receiving Class IA and III antiarrhythmic agents.

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Evidence suggests that sepsis induces diaphragmatic fatigability and that activated neutrophils play a crucial role in the development of diaphragmatic fatigability. In the present study we examined whether the SK channel-mediated effect on PSPs is modified after learning. Effects on pre- and postpartum beef cow performance and calf performance through weaning. Evidence of interrelated side effects with reduced compliance in patients treated with nasal continuous positive airway pressure. The autologous blood was retransfused during the final phases of the procedure. This paper describes an action-research in Lausanne, which aims at the evaluation of the changes that are brought by the introduction of trained cultural mediators and interpreters (CMI) into the medical field.

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An important catecholamines elevation is related with progress or severity of preeclampsia, and could be due to less adrenal injury associated with pregnancy, and contribute to renal failure. Endogenous endophthalmitis is an ophthalmic emergency that can have severe sight-threatening complications. For blends near critical concentration, the introduction of fillers led to much finer phase structure with smaller characteristic length scale. Magnesium and phase angle: a prognostic tool for monitoring cellular integrity in judo athletes. Bone Morphogenetic Protein-2 Induces Donor-Dependent Osteogenic and Adipogenic Differentiation in Human Adipose Stem Cells. The data also offer insight into how exit pathways are influenced by money and relationships that occur within this particular male sex work setting.

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Teaching residents in an ambulatory setting: introducing the concepts of managed care in a fee-for-service clinic. Findings from the study suggest that the four component, 19 item version of the BARRIERS Scale is a robust and valid measure for identifying barriers to research utilization for occupational therapists in paediatric health care settings across Australia, United Kingdom, and Taiwan. Liver receptor homologue-1 and steroidogenic factor-1 expression in cultured granulosa cells from patients with endometriosis: A preliminary study. Influence of electric stimulation parameters on the self stimulation behavior in rats. Pregnancy Medical Home Care Pathways Improve Quality of Perinatal Care and Birth Outcomes. Long-Term Toxicity and Quality of Life in Patients Treated for Locally Advanced Cervical Cancer. These results support the reliable use of tonometry and BIS to assess tissue compressibility and ECF loads in the legs of adolescent populations in developed and developing tropical countries. The preoperative tumor status assessment according to the score as well as that by the experienced sonographer were compared postoperatively with the results of the histological diagnosis. There are limited studies on the factors that can predict the presence of impaired clinical insight specifically in an Emergency Room (ER) psychiatric patient population. All language subsystems were vulnerable to both environmental (type of school) and biological (SLI) effects.

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Domain control of carrier density at a semiconductor-ferroelectric interface. We studied a series of 57 surgical biopsies of astrocytic neoplasms by immunohistochemistry to elucidate the relationship between tumor proliferation, quantified as Ki67-LI, and the expression of these two proteins. Post-intervention, the intervention group had significantly increased treatment control perceptions and decreased medication harm beliefs and concerns. These results also showed that almond cell walls that are completely intact limit lipid digestibility, due to an encapsulation mechanism that hinders the diffusion of lipase into the intracellular environment and lipolysis products out of the cells. Multifunctional DCXs thus represent potential targets for promoting both survival and regeneration of injured neurons. Three-dimensional electroanatomic voltage mapping to guide biopsy sampling in unexplained cardiomyopathies: a proof-of-principle case series. More detailed information is required to elucidate the exact mechanisms as to how insulin analogues may activate the IR and IGF1R and how this activation may be linked to mitogenesis. In a model of subcutaneous tumour inoculation, LCL-30 significantly reduced the proliferative activity and the growth rate of established tumours. The dynamics of the proposed synthetic circuit is investigated with a mathematical model using biologically-meaningful parameters. They can develop as pre-metastatic niches by inflammatory events that are provoked by primary tumors before tumor cell arrival, and/or they can be post-formed by reciprocal signaling between metastasizing tumor cells and local non-tumor cells.

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In order to identify the influence of health care infrastructure, variables related to the number of public and private hospitals are included. We observe rotational state-dependent non-Arrhenius universal scaling laws in chemi-ionization reactions of para-H2 and ortho-H2 by He(2(3)P2), spanning three orders of revia 50 mg side effects magnitude in temperature. Overall, American Academy of Pediatric Dentistry patient education materials were difficult to read and written above the recommended level for the general public using accepted measures. Skeletonized IMAhad superior flow to pedicled IMAin addition to its traditional proven advantages, which justifies its further use as a conduit for myocardial revascularization. These results indicated that bergenin bound to HSA mainly by a hydrophobic interaction in microemulsions which was in agreement with the result of the molecular modeling study. In this study, using gene-targeted deficient mice, we evaluated P-selectin and its contribution to PMN and platelet adhesion in hepatic damage. Since 1905 major epidemics of meningococcal meningitis have occurred in countries of the Sahel and sub-Sahel every few years, culminating in a massive epidemic in which nearly 200,000 cases were reported in 1996.

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Novel antennal amiloride 5 mg lobe substructures revealed in the small hive beetle Aethina tumida. In general, findings supported the convergent validity of BCT category learning, set loss, and memory subscales. Our findings suggest successful and sustained modulation of gene expression through healthy lifestyle changes may have beneficial effects on vascular health that cannot be discerned from traditional risk factor profiles. Dysthymic disorder is a relatively common illness that is often treated with antidepressants. Outcome comparison between open and endovascular management of axillosubclavian arterial injuries.

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In this study, we investigated the spatiotemporal localization of C. Generally, placental weight is reduced during suboptimal conditions like maternal malnutrition or hypoxaemia but compensatory adaptations can occur in placental nutrient transport capacity to help maintain fetal growth. Graphic illustrations to visually display and quantify cell shape are presented along with algorithms and formulae for calculating select 2D and 3D motion analysis parameters. Sex is an important variable that will need to be taken into account in future studies evaluating the potential clinical effects of photo-protecting TPN. Strategies for managing health problems among homeless women: three case studies. The results revealed that synaptic depression reduces neural correlation, which could be beneficial for sensory coding. In an attempt to resolve the problem of amyloid deposition in dialysis patients, we used HPIAC to specifically remove beta2-microglobulin from human plasma.

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Bacterial infection as an important triggering factor in bronchial asthma. The sucking, Babinski and Moro reflexes were assessed and classified by normal, abnormal and absence. She presented with quadriparesis due to dumbbell-shaped spinal schwannoma in the cervical region. There are many fundamental processes where the same (i.e., chemically identical) porphyrin cofactor is involved in chemically quite distinct reactions. Time-dependent striatal dopamine depletion after injection of 6-hydroxydopamine in the rat. These results indicate that MST, combat exposure, and negative urgency independently predict PTSD symptoms and PTSD symptoms mediate their relationship with alcohol-related problems. Reduced absorption and altered metabolism are the likely cause of these changes. With increasing availability of electronic medical records (EMRs), automated early warning scores (EWSs) are becoming feasible.

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