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Bifosa (Alendronate)
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Bifosa

Bifosa is used to prevent and treat certain types of bone loss (osteoporosis) in adults. Osteoporosis causes bones to become thinner and break more easily. Your chance of developing osteoporosis increases as you age, after menopause, or if you are taking corticosteroid medications (such as prednisone) for a long time.

Other names for this medication:
Alant, Alendix, Alendronate, Alenost, Bifosa, Denfos, Osteofos, Ostogee, Poronil, Ralenost, Restofos, Zophost

Similar Products:
Dulcolax, Aristocort, Thorazine, Depakote, Dramamine, Calan, Ovral, Vasotec, Naprosyn

Also known as: Alendronate

Description

Generic Bifosa is a drug which helps to fight with postmenopausal osteoporosis, steroid-induced osteoporosis, Pagets disease of bone. Generic Bifosa is a medicine which belongs to the group of medicines called bisphosphonates. Bifosa is also known as Alendronic acid, Alendronate sodium, Ostofos. Generic Bifosa works by preventing bone breakdown and increasing bone density (thickness). Generic name of Generic Bifosa is Alendronate. Brand name of Generic Bifosa is Bifosa.

Dosage

Take Bifosa exactly as prescribed by your doctor. Bifosa is taken either once daily or once per week. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended.

Take Bifosa first thing in the morning, at least 30 minutes before you eat or drink anything or take any other medicine. If you take this medicine only once per week, take it on the same day each week and always first thing in the morning.

Take with a full glass (6 to 8 ounces) of plain water. Do not use coffee, tea, soda, juice, or mineral water. Do not eat or drink anything other than plain water.

Do not crush, chew, or suck on an Bifosa tablet. Swallow the tablet whole.

For at least 30 minutes after taking Bifosa:

Do not lie down or recline. Do not take any other medicine including vitamins, calcium, or antacids.

Pay special attention to your dental hygiene while taking Bifosa. Brush and floss your teeth regularly. If you need to have any dental work (especially surgery), tell the dentist ahead of time that you are using alendronate.

Bifosa is only part of a complete program of treatment that may also include diet changes, exercise, bone mineral density testing, and taking calcium and vitamin supplements. Follow your doctor's instructions very closely.

Store at room temperature away from moisture and heat.

Your doctor will determine how long to treat you with this medicine. Bifosa is often given for only 3 to 5 years.

Detailed Bifosa dosage information

Overdose

Drink a full glass of milk and seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not make yourself vomit and do not lie down.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bifosa are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not take Bifosa Plus D if you have low levels of calcium in your blood (hypocalcemia), or a problem with the movement of muscles in your esophagus.

Do not take a Bifosa Plus D tablet if you cannot sit upright or stand for at least 30 minutes. Alendronate can cause serious problems in the stomach or esophagus (the tube that connects your mouth and stomach). You will need to stay upright for at least 30 minutes after taking Bifosa Plus D.

To make sure Bifosa Plus D is safe for you, tell your doctor if you have:

low blood calcium (hypocalcemia); a cancer such as sarcoidosis, leukemia, lymphoma; a vitamin D deficiency; kidney disease; or an ulcer in your stomach or esophagus.

In rare cases, this medicine may cause bone loss (osteonecrosis) in the jaw. Symptoms include jaw pain or numbness, red or swollen gums, loose teeth, or slow healing after dental work. The longer you use Bifosa Plus D, the more likely you are to develop this condition.

Osteonecrosis of the jaw may be more likely if you have cancer or received chemotherapy, radiation, or steroids. Other risk factors include blood clotting disorders, anemia (low red blood cells), and a pre existing dental problem.

Talk with your doctor about the risks and benefits of using this medication.

It is not known whether Bifosa Plus D will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication.

It is not known whether alendronate and cholecalciferol passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

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Density-functional theory (DFT) and ab initio calculations have been used to investigate the effect of a complexed lithium cation on the radical-clock rearrangement of the 2-norcaranyl radical to the 3-cyclohexenylmethyl radical. Transient expression of B19 parvovirus gene products in COS-7 cells transfected with B19-SV40 hybrid vectors. In the adherens junction beta-catenin and plakoglobin serve to link classical cadherins to the actin-based cytoskeleton. The Malay and English versions of the ADDQoL questionnaire were administered to patients attending routine outpatient visits in three primary hospitals and a public clinic. This contribution addresses the problem of solute dispersion in a free convection electrophoretic cell for the batch mode of operation, caused by the Joule heating generation. There was no relationship between the density of each endocrine cell type and fetal age, but there was a significant increase in the relative density (percentage total endocrine cells) of D cells from 10-20 weeks (p less than 0.01). Moreover, cytotoxicity of the released vancomycin was assessed using osteoblast cultures, and after 14 days of culture in the presence of vancomycin, cells were able to remain viable, increasing their metabolic activity and colonizing the granules, as observed by scanning electron microscopy and confocal laser scanning microscopy. Dihydrate birefringent calcium oxalate or Weddellite calcification. To discover genetic polymorphisms among these varieties, five loci within the nuclear and chloroplast genomes were screened.

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In a Dutch sib pair, a shared 9-Mb homozygous region was found on 11q13.1-q13.5 that encompasses the CABP4 gene, previously implicated in autosomal recessive incomplete congenital stationary night blindness (CSNB2) in two small families. This original case report may benefit both gynecologic oncologists and female pelvic surgeons and reconstructive surgeons to keep urethral diverticulum in the differential diagnosis when faced with a bleeding midline anterior vaginal mass. Chemical modification of the amino groups and the guanido groups in cranberry bean alpha-amylase inhibitor molecule resulted in rapid loss of the inhibitory activity, respectively. Chikungunya: a paradigm of emergence and globalization of vector-borne diseases. Sleep curtailment is accompanied by increased intake of calories from snacks. It is unclear whether these abscesses differ in presentation or other characteristics from their non-MRSA counterparts. Aryl Hydrocarbon Receptor Activation Down-Regulates IL-7 and Reduces Inflammation in a Mouse Model of DSS-Induced Colitis. NTCP was calculated for seven organs by postulating a dose distribution of maximum nonuniformity. jostii, showed TDG degradation activity only when grown in the presence of TDG as the sole sulfur source.

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Adjuvant activity of naturally occurring monophosphoryl lipopolysaccharide preparations from mucosa-associated bacteria. Animal research versus humane use: the struggle to sustain our research advances. Detailed knowledge regarding the acquisition and transmission of infectious agents facilitates a more comprehensive approach toward prevention. Considerable effort is needed by key players to bring current vaccine candidates through phase III clinical trials and there is a clear need to develop a roadmap for future development of current and new candidates. The average third of the left uterine horn was removed, 4mm x 4mm patches in liquid environment were made, and self-transplanted in the rat mesenterium with a single stitch, and the endometrial surface of the endometriotic implant facing the lumen of the peritoneal cavity. Diagnosis may be easily established in the light of clinical history, which can be aided by imaging studies to pinpoint the exact location. Optical section retinal images, generated in normal human eyes using a modified slit-lamp biomicroscope, were analyzed to derive the double-pass LSF by plotting the intensity distribution of laser light reflected/ scattered from the vitreoretinal interface.

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Tumor cells express TF and spontaneously release TF-positive microparticles (MPs) into the blood. The extent of the induction inversely correlated with the severity of mucosal lesions, suggesting an important role of HSP70 in gastric mucosal defence. Total thyroidectomy is the accepted standard treatment for benign goitrous enlargements. Multi-institutional prospective studies may better identify patients at high risk. Inconsistent with other cross-sectional studies mostly conducted in industrialized countries, our study indicates that exposure to animals may increase the occurrence of respiratory symptoms and diseases in children, and the associations with respiratory symptoms strengthened with higher levels of animal exposure parental atopy did modify the effect of pet exposure on persistent phlegm but not on doctor-diagnosed asthma. However, it was also found to be actively secreted by both mf and adult worms. A current and charge conserving scattering theory is presented that accounts for this observation with a relaxation time given by the electronic transit time in the circuit. Both TDF and SRM are safe and effective analgesics for the management of chronic cancer pain. Changes in KIT scores by treatment group showed numerically greater and more often statistically significant improvements from baseline to each assessment for children receiving romiplostim versus placebo. Effect of interleukin-1-beta and tumor necrosis factor-alpha on cartilage proteoglycan metabolism in vitro.

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Quantitative assessment of marine sponge cells in vitro: development of improved growth medium. Notably, the use of a preorganized zinc source led to drastic changes in the formation rate of ZIF-8. This technique has been applied to the study of RNA synthesis in the course of regeneration. Colonoscopic localization accuracy for colorectal resections in the laparoscopic era. In contrast to native Wld(S) mutants, distal axon stumps remained continuous and ultrastructurally intact up to 7 weeks after injury and motor nerve terminals were robustly preserved even in older mice, remaining functional for 6 d.

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Semantic differential scores of white and nonwhite respondents favored the receiver-assisted version, indicating that the materials are appropriate for use with a racially mixed target audience. Firm size and occupational injury and illness incidence rates in manufacturing industries. To describe a method for performing computed tomography (CT)-guided hookwire localization using a radial approach for metallic marker clips placed percutaneously after SVAB. To elucidate their structures, metabolites were isolated and analyzed by mass spectrometry and nuclear magnetic resonance spectroscopy. Association of these genes with susceptibility to RA was analyzed both independently and after stratification by one of the genotypes. Aged DBA/2 mice may constitute a useful model for senile unilateral cataract, probably caused by early uveitis. The committee created a database of tests used to diagnose and monitor dry eye, each compiled by an expert in the field (rapporteur) and presented within a standard template. In recent years, it has been shown that glutamate can also be toxic to white matter oligodendrocytes and to myelin by this mechanism.

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Did FDA Decisionmaking Affect Anti-Psychotic Drug Prescribing in Children?: A Time-Trend Analysis. It is concluded that this formulation has no effect on starch digestion in humans. This preferential growth of tumor cells in the presence of tissue specific stroma may be used as an in vitro model for the study of the role of stromal cells in tumor cell spread. This study aimed to determine whether the MS and MV patterns in ME-NBI differ according to the histologic type, invasion depth, and mucin phenotype of early gastric cancers (EGCs). The use of immersion hypothermia on the ipsilesional UE in association with sensory training of the contralesional UE improved motor function and sensitivity in the contralesional UE of individuals with chronic stroke. Cerebellar ataxia with elevated cerebrospinal free sialic acid (CAFSA). The generation of spectral mutants of the green fluorescent protein (GFP) set the stage for multiple-color imaging in living cells.

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Interestingly, pre-treatment of experimental animals with zymosan boosted strong immunological memory as compared to archaeosome encapsulated Rv3203 as well as BCG vaccine. We also found that subjects with Jewish ancestry were slightly more heterozygous than the subjects with no Jewish ancestry, suggesting that the genetic distinction between Jews and non-Jews may be more attributable to a Near-Eastern origin for Jewish populations than to population bottlenecks. Airborne contamination associated with in-use air-fluidized beds: a descriptive study. Preclinical evaluation was performed in a subcutaneous murine human glioma xenograft (U87MG). The results show significant slowing of the EEG in people with neuropathic pain, consistent with the presence of thalamocortical dysrhythmia (TCD). The use of a contrast agent significantly improved perfusion characterization. Adherence to treatment guidelines for ovarian cancer as a measure of quality care. Fertility outcome after ectopic pregnancy and use of an intrauterine device at the time of the index ectopic pregnancy. The goal of treatment is to eradicate the infection when possible, although chronic suppression may be adequate for patients with AIDS and other serious immunosuppressive disorders.

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