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Bigomet (Metformin)

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Bigomet is used with a proper diet and exercise program and possibly with other medications to control high blood sugar. It is used in patients with type 2 diabetes. Bigomet works by helping to restore your body's proper response to the insulin you naturally produce. It also decreases the amount of sugar that your liver makes and that your stomach/intestines absorb.

Other names for this medication:
Bemet, Chromet, Dibimet, Dokmet, Etformin, Exmet, Forminal, Fortamet, Glumetza, Glycirest, Matce, Mesite, Metforise, Metmin, Metsig, Mintide, Nilconorm, Ovinom, Pioglar, Piokap, Risicon, Rosizon, Tenliptin, Triglucored, Voglinorm, Walaphage, Zetfor

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Also known as: Metformin


{name} (metformin) is an oral diabetes medicine that helps control blood sugar levels.

{name} is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

{name} is sometimes used together with insulin or other medications, but metformin is not for treating type 1 diabetes.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Take Bigomet XR with a meal, unless your doctor tells you otherwise. Some forms of metformin are taken only once daily with the evening meal. Follow your doctor's instructions.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

Measure liquid medicine carefully. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).

Some tablets are made with a shell that is not absorbed or melted in the body. Part of this shell may appear in your stool. This is normal and will not make the medicine less effective.

You may have low blood sugar (hypoglycemia) and feel very hungry, dizzy, irritable, confused, anxious, or shaky. To quickly treat hypoglycemia, eat or drink a fast-acting source of sugar (fruit juice, hard candy, crackers, raisins, or non-diet soda).

Your doctor may prescribe a glucagon injection kit in case you have severe hypoglycemia. Be sure your family or close friends know how to give you this injection in an emergency.

Blood sugar levels can be affected by stress, illness, surgery, exercise, alcohol use, or skipping meals. Ask your doctor before changing your dose or medication schedule.

Bigomet XR is only part of a complete treatment program that may also include diet, exercise, weight control, blood sugar testing, and special medical care. Follow your doctor's instructions very closely.

Store at room temperature away from moisture, heat, and light.

Your doctor may have you take extra vitamin B12 while you are taking Bigomet XR. Take only the amount of vitamin B12 that your doctor has prescribed.

Detailed Bigomet XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Bigomet are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use MetFORMIN (Eqv-Bigomet XR) if you are allergic to it, or if you have:

severe kidney disease; or metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking MetFORMIN (Eqv-Bigomet XR). Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine); high ketone levels in your blood or urine; heart disease, congestive heart failure; liver disease; or if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

MetFORMIN (Eqv-Bigomet XR) may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

MetFORMIN (Eqv-Bigomet XR) should not be given to a child younger than 10 years old. Some forms of MetFORMIN (Eqv-Bigomet XR) are not approved for use by anyone younger than 18 years old.

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Cytological studies in precancerous and cancerous processes and adenomas of the stomach. We conclude that the requirements for appreciable metabolism by 5-HEDH include a chain length of at least 16 carbons, a free alpha-carboxyl group, and a hydrophobic group at the omega-end of the molecule. mansoni, rather than the distribution of hookworm, and that temperature, elevation and distance to large water bodies are reliable predictors of the spatial large-scale distribution of co-infection. A novel steroid, (7 alpha,17 alpha)-17-hydroxy-7-methyl-19-norpregn-5(10)-en-yn-3-one (code name Org OD 14), was found to possess concomitant weak oestrogenic, androgenic and progestational activities. Crude incidence and mortality rates of esophageal cancer were estimated. Outcomes and Resource Utilization of Endoscopic Mass-Closure Technique for Laryngeal Clefts. In plants that utilize the less common single cell C4 system, Rubisco accumulates only within one type of dimorphic chloroplasts localized to a specific region of leaf chlorenchyma cells. 9-h), number of early morning shifts, number of midnight shifts, and schedule preference. Fifty patients requiring thigh donor-site split skin grafts were prospectively randomized to receive either a self-adhesive fabric dressing alone or fibrin sealant plus the self-adhesive fabric dressing as primary donor-site dressings.

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Immune-mediated limbic encephalitis-tip of the iceberg in childhood autoimmune epilepsy. The indirect secondary electron contrast (ISEC) condition of the scanning electron microscopy (SEM) produces high contrast detection with minimal damage of unstained biological samples mounted under a thin carbon film. Thermo-responsive chitosan microbubbles were developed as new therapeutic device for vehiculating gases to tissues concomitantly to hyperthermic treatments. Ready or not, here they come: randomized trials evaluating new endovascular aneurysm therapies. Binding properties of human anti-DNA antibodies to cloned human DNA fragments. These cells are available from the American Type Culture Collection as ATCC CRL 2523. The similar activity of beta-agonists in these tests and the ability of T3 to potentiate the effect of clenbuterol agree with the hypothesis that T3 can induce beta-adrenergic hypersensitivity. The detectors in this study consist of an active layer and a polyvinylidene fluoride (PVDF) blocking layer, which are sandwiched by an aluminum and an indium tin oxide (ITO) electrode.

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This report characterizes a spontaneously arising TIGR4 mutant exhibiting a reduced capsule, caused by a 6-nucleotide duplication in cpsE which results in duplication of Ala and Ile at positions 45 and 46. When the release recorded in the presence of the steroid is plotted against the release recorded in its absence, the data points of several experiments fit a regression line characterized by two parameters: its slope and its intercept with the abscissa. The aim of this study is to evaluate radiation exposure resulting from the comprehensive health examinations of selected university hospital programs and to present basic data for research and management strategies on the health effects of medical radiation exposure. Assessment of a real-time PCR test to diagnose syphilis from diverse biological samples. However, methods to capture cells for functional downstream analyses are limited due to inaccessibility of the captured sample or labeling techniques that may be prohibitive to cell function. The predicted structures are compared with those postulated from NMR spectroscopy in relation to the formation of a cation-binding site. The mechanism of assembly of Acanthamoeba myosin-II minifilaments: minifilaments assemble by three successive dimerization steps. Despite mounting evidence supporting fecal transplantation (FT) as a treatment for recurrent Clostridium difficile infection (CDI), adoption into clinical practice has been slow.

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Interobserver variability in CT scan interpretation for suspected acute appendicitis. This review defines terms such as accuracy, validity, and reliability, which are used to describe the quality of methods for taking x-rays and for analyzing digital images. Clinical significance and effects of foreign body embolism during the use of central venous catheters. It had good microsomal stability when incubated with rat and human liver microsomes and showed no significant cytochrome P450 (CYP) inhibition. An electric field built tenormin 25 mg dosage inside a crystal was proposed to enhance photoinduced carrier separation for improving photocatalytic property of semiconductor photocatalysts. The risk factors with statistical significance in conditional logistic regression analysis were exposure time of smelting, time of underground drilling, and age of beginning mining underground.

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Functional analysis of the molecular interactions of TATA box-containing genes and essential genes. Development of a certified reference material for genetically modified potato with altered starch composition. Although the limitations of implementing the mitigation hierarchy have been widely discussed in scientific literature, these studies have drawn mainly on feedback concerning terrestrial ecosystems. Gingival sulcular epithelium--which in primates normally does not keratinize--can be induced to undergo keratinization by prolonged intensive antibacterial therapy. In the present study we investigated the mechanism by which GT reduces NO production. Vascular endothelial growth factor and its relationship to inflammatory mediators. Here, we established receptor and cell signalling profiles of 17 therapy-relevant factors and propose a molecular diagnostic algorithm for SGC. Separate groups of rats were given 30 pairings of a light (conditioned stimulus, CS) and 500-ms shock (unconditioned stimulus, US) at CS-US intervals of 0, 25, 50, 100, 200, 800, 3,200, 12,800, or 51,200 ms.

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