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Biozyl (Metronidazole)

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Biozyl is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Aldezol, Aldezole, Aminidazole, Anamet, Anazol, Asuzol, Biozyl, Deflamon, Dequazol, Filmet, Ginerella, Medamet, Metrofusin, Metrogyl, Metronidazol, Metronidazole, Metronour, Metrosept, Metrosil, Metrozine, Metrozole, Metryl, Micogyl, Minegyl, Negazole, Nizole, Onida, Padet, Perilox, Pharmaflex, Protogyl, Protozol, Repligen, Rosazol, Rosiced, Rozacrme, Rozamet, Rozex, Rupezol, Servizol, Taremis, Tolbin, Trichostatic, Trichozole, Tricodazol, Vandazole, Vertisal

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Also known as: Metronidazole


{name} (metronidazole) is an antibiotic that is used to treat bacterial infections of the vagina, stomach, liver, skin, joints, brain and spinal cord, lungs, heart, or bloodstream.

{name} is also used to treat trichomoniasis, a sexually transmitted disease caused by a parasite. Usually both sexual partners are treated at the same time, even if one has no symptoms.

Do not use {name} to treat any condition that has not been checked by your doctor.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Biozyl ER. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.


If you overdose Generic Biozyl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Biozyl overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Biozyl ER dosage information

Side effects

The most common side effects associated with Biozyl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Biozyl if you are allergic to metronidazole, secnidazole, or tinidazole, or if:

you recently drank alcohol; or you took disulfiram (Antabuse) within the past 14 days.

Do not take metronidazole during the first trimester of pregnancy. This medicine can harm an unborn baby. Tell your doctor if you are pregnant.

To make sure Biozyl is safe for you, tell your doctor if you have ever had:

liver disease; kidney disease (or if you are on dialysis); a heart rhythm disorder; Cockayne syndrome (a rare genetic disorder); a stomach or intestinal disease such as Crohn's disease; a blood cell disorder such as anemia (lack of red blood cells) or low white blood cell (WBC) counts; a fungal infection anywhere in your body; or a nerve disorder.

In animal studies, metronidazole caused certain types of tumors, some of which were cancerous. However, it is not known whether these effects would occur in humans. Ask your doctor about your risk.

You should not breastfeed within 24 hours after using Biozyl. If you use a breast pump during this time, throw out any milk you collect. Do not feed it to your baby.

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Taken together, these results implicate the CDK-pRb/E2F/DP pathway as a required element in the neuronal death evoked by DNA damage. Neurologic sequelae of neonatal hypoglycemia in Kayseri, Turkey. Special attention should be paid to women and more obese patients due to higher incidence of depression in these groups. Difficulties and errors in the parasitologic diagnosis of malaria. These results, in conjunction with the documented in vitro biological activities of the arachidonate epoxygenase metabolites, suggest a role for them in renal function. The present experiments investigated the validity and utility of measuring the habituation of a nose-poke response to assess memory in mice. This article discusses the principles, methods, and benefits of CT scans and 3-D imaging for the custom design of facial implants for aesthetic and reconstructive surgery. Various authors suggest that programmed cell death (PCD) is attenuated in cancer cells due to a reduced activity of DNase-I. To investigate the challenges of the New Zealand healthcare disaster preparedness prior to the Canterbury earthquakes.

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The phenotype of antigen-specific suppressor T cells generated in human mixed leucocyte culture depends on the nature of the major histocompatibility regions recognized. Breast scanning is recommended in cases in which mammography alone is of limited value, including dense fibrocystic breasts in women at high risk, follow-up in breast cancer patients after breast conserving therapy, in patients with silastic implants and in the follow-up of breasts with huge scars due to multiple biopsies. Identification of iPhone and iPad applications for obstetrics and gynecology providers. To investigate the in vitro effects of NPY with DPP-IV inhibition in isolated abdominal subcutaneous (AbdSc) adipocytes on fat metabolism, and assessment of NPY receptor and DPP-IV expression in adipose tissue (AT). Among the many determinants of nucleosome positioning, the DNA sequence has been proposed to have a major role.

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To assess the use of unenhanced spiral computed tomography (CT) as the primary investigation of choice for suspected acute renal colic in clinical urological practice. We examined the positive predictive values (PPVs) of hospital ICD-9-CM diagnoses in identifying SALI among health plan members in the Mini-Sentinel Distributed Database (MSDD) for patients without liver/biliary disease and for those with chronic liver disease (CLD). However, recent studies have shown that in some face-to face collaborative situations, or when recipients express their desires, children at much younger ages choose equal allocations. An important, and usually neglected, aspect of the use of the system is illustrated by the presentation of some quantitative data from the review of a dental care program. Therapeutical use of anti-inflammatory nutraceuticals directly targeting MC activation could be of interest for afflicted patients. Adults in psychiatric outpatient care frequently reported stigma experiences related to aspects of their sexual lives. It is possible to use our estimates to obtain a confidence range for true heritability when we have information about approximate location of threshold and estimates of heritability obtained by linear model. The remaining cell types have short dendrites which branch for three or four generations and follow a tortuous course. Scientific medical information and its role in the activities of paramedical workers. Recent criminal acts in the United Kingdom, United States and other countries have demonstrated the dangers to public safety from the criminal use of improvised explosives on a large scale.

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Using the NTP database to assess the value of rodent carcinogenicity studies for determining human cancer risk. The investigation and comparison of some features of the internal structure of brachial plexus cords gave interesting results, which are collected in this paper. A report of a further hospital outbreak caused by a multi-resistant Acinetobacter anitratus. Relationship between the integrity of the pelvic floor muscles and early recovery of continence after radical prostatectomy. Biochemical fractionation reveals that both CRD1 and CTH1 are localized to chloroplast envelope as well as thylakoid membranes. Most of all, BrSARS-N proteins were expressed as a highly phosphorylated form with a molecular mass of 48kDa, but ErSARS-N was a nonphosphorylated protein. In Japan, the mortality from CVD, especially stroke, has declined continuously from the 1960s to the 2000s, which has contributed to making Japan into the top-ranking country for longevity in the world.

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This study provides empirical and practical evidence from nurses who perform novel clinical interventions that specifically promote independent living. In our study 6 patients with end-stage renal disease on RHT, underwent, daily and for ten days, two-hours hemoperfusion, in order to obtain lower levels of toxic metabolites such as creatinine (less than 6 mg/dl.). In this study, the effect of the Arbuscular Mycorrhizal fungus Glomus etunicatum on the physiological growth parameters of tomato (Lycopersycium esculentum Mill) plants on the toxicity level of copper was investigated. Correlation between the measurements was examined by regression analysis. Patients expect effective pain relief after surgery, without side effects, and this may not always be possible when more complicated procedures are performed in ambulatory settings. He had a past history of acute lymphoblastic leukemia (ALL), which subsided in response to chemotherapy at 3 years of age.

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These results suggest that introspective estimates of time spent on a task tightly correlate with the period of availability of central processing resources. Inhibition of MAP kinase activity with PD98059, a specific inhibitor of MAPKK-1, or by transfection of a dominant-negative MAPKK-1 mutant antagonized the antiapoptotic effect of ET-1, suggesting the involvement of MAP kinase in the antiapoptotic effect. Although low numbers of verb contexts made it difficult to evaluate the linguistic variables, there was evidence of their influence, especially for verb regularity and negation. The methodology is valuable for identifying main and secondary responses associated with the experimental factors and spotting relevant experimental conditions. Food allergy knowledge among parents of food allergic children from the Netherlands is suboptimal when compared with their counterparts from the USA, although these parents tend to be more optimistic toward food allergy than parents from the USA. The purpose of this study was to identify knowledge deficits concerning nosocomial pneumonia (NP) prevention among critical care nurses. Fatal latrogenic exsanguination from pleural drain insertion into the inferior cava. We have previously demonstrated that a high proportion of CSF plasma cells of NMO patients produce antibody to the extracellular domains of the AQP4 protein and that recombinant IgG (rAb) derived from these cells recapitulate pathogenic features of disease.

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The specific expression and distribution of S100P in human placenta throughout gestation suggested that S100P function might vary with its location in the placenta. Here we report that S100B significantly increases the activity of ERK in primary cultures of astrocytes, a result which may be related to previous observations of the effect of this protein on glial proliferation. A new synthetic procedure is described for the preparation of poly(organo)phosphazenes with star-branched and star dendritic molecular brush type structures, thus describing the first time it has been possible to prepare controlled, highly branched architectures for this type of polymer. Evolution of the HCV viral population from a patient with S282T detected at relapse after sofosbuvir monotherapy. The aim of this study was to analyze the rate of clinically inapparent common bile duct (CBD) stones, the predictive value of elevated liver enzymes for CBD stones, and the influence of the radiological results on the perioperative management. To evaluate how IFN-gamma production in the upper and lower airway is associated with localized bacterial sinusitis.

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A recombinant Charon 4 bacteriophage has been isolated on the basis of RNAs which are enriched in the head of the adult Drosophila melanogaster and hence are likely to be of neural origin. Influence of bench angle on upper extremity muscular activation during bench press exercise. In this study we determined the capacity of ST3GAL3 and ST3GAL4 sialyltransferases to synthesize the SLe(x) antigen in MKN45 gastric carcinoma cells and evaluated the effect of SLe(x) overexpression in cancer cell behavior both in vitro and in vivo using the chicken chorioallantoic membrane (CAM) model. We investigated the effects of chronic ethanol consumption on the cavernosal smooth muscle (CSM) reactivity to endothelin-1 (ET-1) and the expression of ET system components in this tissue. Femoral marrow was either cultured as a single cell suspension immediately following collection from the donor mouse or following 4 day incubation in vitro of the whole marrow shaft. Rapamycin and CTLA4Ig synergize to induce stable mixed chimerism without the need for CD40 blockade. The management of behavioural and psychological symptoms of dementia in the acute general medical hospital: a longitudinal cohort study. However, cardiac failure may occur later in life due to progressive enlargement of the fistula. Bleomycin pulmonary toxicity: its relationship to renal dysfunction. Promoting patient-centered preventive care using a wellness portal: preliminary findings.

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Each had an enlarged, contrast-enhancing pituitary gland by computed tomographic scan and a markedly supranormal serum concentration of glycoprotein alpha subunit. Expression of PA system mRNAs was analysed by cDNA microarrays and real-time quantitative RT-PCR. Mucosal microcirculation was assessed using pCLE in the stomach, duodenum, terminal ileum, and rectum. Suppression by tetrandrine of human platelet aggregation induced by platelet-activating factor and other stimulants. Parathyroidectomy (PTX) is often performed in dialysis patients when medical treatment fails to control secondary hyperparathyroidism (SHPT). The rate of recurrence at the surgical margin was low and a positive margin was not associated with an increased risk of recurrence either at the surgical margin or elsewhere. Recently, peripherally inserted central venous catheters (PICCs) have been widely used for venous access. Physical activity was assessed using heart rate monitoring over four days. We present plausible assignments for this state as a guide for future experimental work. Atrial fibrillation (AF) is the most common cardiac arrhythmia, with a projected number of 1 million affected subjects in Germany.

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Patients were classified according to American Diabetes Association guidelines for target HbA1c levels per age group. Simple options for improving signal detection in antidepressant clinical trials. Oxygen availability and spreading depolarizations provide complementary prognostic information in neuromonitoring of aneurysmal subarachnoid hemorrhage patients. Each country reported isolations of H5N2 virus from poultry and the large-scale use of inactivated and recombinant H5 vaccines in their AI control programs. From 2001 to 2014, the total number of cases of occupational diseases was 958. Survey of clinical doses from computed tomography examinations in the Canadian province of Manitoba. The fellowship: Gilbert, Bacon, Harvey, Wren, Newton, and the story of a scientific revolution.

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Protease inhibitor suppression of influenza virus replication in the lungs of infected mice. Technical refinements in the surgical treatment of gynecomastia. To investigate the effects of depside salts from Salvia miltiorrhiza on myocardial microperfusion and systemic hemodynamics in open-chest anaesthetized Sprague-Dawley rats. Recombination in diverse maize is stable, predictable, and associated with genetic load. HCWs were observed conducting lipitor 20mg tab venous and capillary blood collections, and pre- and posttests were offered during HCW training. This chiral stationary phase was applied to the enantioselective and diastereoselective separation of five pyrethroid insecticides by HPLC under normal phase condition. In mammals, endothelial nitric oxide synthase (eNOS) has the weakest activity, being one-tenth and one-sixth as active as the inducible NOS (iNOS) and the neuronal NOS (nNOS), respectively. Isolated choroid plexus cysts, cardiac defects not requiring treatment, mild ventriculomegaly, and mild renal pelviectasis in second trimester were not included. The metabolic pathways in apicoplasts of human malaria parasites are promising drug targets. The metastatic lymph nodes around the superior mesenteric arterial root macroscopically remained.

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Here, we affinity purified mitochondria and used quantitative mass spectrometry to determine how the mitochondrial proteome changes upon HCMV infection. Immunostimulatory AdCD40L gene therapy combined with low-dose cyclophosphamide in metastatic melanoma patients. Impulse attack free double-random-phase encryption scheme with randomized lens-phase functions. A longitudinal study of craniofacial growth in idiopathic short stature and growth hormone-deficient boys treated with growth hormone. An evidence-based dentistry challenge: treating patients on warfarin (Coumadin).

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For example, when we estimate T lymphocyte chemotaxis, we collected nylon-wool nonadherent peripheral blood lymphocytes (PBL) and confirmed their purity by sheep erythrocytes rosette formation assay. To place the process of synthesising the research literature into context, the article explores the critiquing process by breaking it down into seven sequential steps. Initial in silico analysis of the Tasmanian devil genome and experimental screening in the seven marsupial orders revealed 20 informative transposable element insertions for resolving the inter- and intraordinal relationships of Australian and South American protonix medication type orders. Nonetheless, several preliminary evidences suggest that new antibodies, cancer vaccines and adoptive transfer of lymphocytes, genetically engineered to acquire NB specificity, may result in clinical benefit, and clinical studies are currently ongoing. Renewable dehydrogenase-based interfaces for bioelectronic applications. The aim of this review is to analyze the gradients present in the OC interface from the early stage of embryonic life up to the adult organism, and give an overview of the studies, which involved gradient scaffolds for its regeneration. Here, we review the molecular regulation of T cell exhaustion, placing recent findings on PD-1 blockade therapies in cancer in the context of the broader understanding of the roles of the PD-1:PD-L1 pathway in T cell exhaustion during chronic infection. The conformational epitopes recognized by mAbs with neutralizing activity against both PCV1 and PCV2 were detected in transfected PK-15 and the residues 231-233 also participated in the formation of conformational epitopes. Selective lymph node dissection in patients with intermediate thickness melanoma: our experience.

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A survey among members of the American Association for Pediatric Ophthalmology and Strabismus yielded five patients who received cycloplegic eye drops between 1998 and 2010 and who consequently developed a seizure. After persantine dosing statistically controlling for alcohol and tobacco use and adequacy of prenatal care, physicians had a 1.86 (1.00, 3.46) relative risk of an adverse pregnancy outcome. The reference group consisted of patients with haemoptysis or suspected of having bronchial carcinoma. Indecision in the clinical practice of anticoagulation for brief atrial arrhythmias after cryptogenic stroke. We performed ultrasound biomicroscopy in supine and prone positions for eight directions and specular microscopy for nine directions. METHODS: The authors have reviewed data on recent and active phase I and phase II trials of several new agents and combinations.

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Dialectical behavior therapy for high suicide risk in individuals with borderline personality disorder: a randomized clinical trial and component analysis. This truncated form of PKCzeta enhanced JNK and caspase-3 activation. In addition, new opportunities in mucosal immunity via nasal vaccination as well as the elusive nose to brain uptake continue to drive innovation. Twenty patients who underwent endovascular treatment for acute complicated aortic dissection were evaluated for computed tomographic (CT) findings of the aorta and affected end organs. activation by pinacidil, inhibition by glibenclamide and activation by intracellular UDP. Our terazosin 1 mg capsule data strongly suggests that HDACi induce apoptosis primarily through inactivation of anti-apoptotic Bcl-2 family members by increases in Bim and Noxa and highlights these increases as a potential clinical target for CLL/lymphoma therapy. Immunohistochemical staining of CD3 was performed to assess the number of tumor infiltrating T lymphocytes (TILs) in thyroid cancers. This practice causes more frequent transgene silencing due to a high degree of sequence homology and a greater chance of rearrangement among repeatedly used promoter sequences.

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