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Brosol (Albuterol)
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Brosol

Brosol is a medication that opens up the medium and large airways in the lungs. It is used to treat asthma, including asthma attacks, exercise-induced bronchoconstriction, and chronic obstructive pulmonary disease (COPD). It was approved for medical use in the United States in 1982.

Other names for this medication:
Accuneb, Aerocort, Aerotaz, Aerotide, Alernyl, Ancoril, Asmanil, Asthalin, Avasth, Benylin, Brolax, Bronchosol, Broncof, Bronkotab, Bronsim, Brorex, Brosol, Budesal, Derihaler, Derivent, Eascof, Esmasol, Exporil, Lebasma, Ophyl, Pencolin, Pherin, Proventil, Pulmovent, Respisol, Rivoryl, Salbair, Salbrosin, Servent, Shwas, Silicof, Somavent, Suprivent, Swicof, Ventorlin, Ventosol, Viscof, Vospire

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Also known as: Albuterol

Description

Albuterol is used to treat bronchospasm or wheezing in patients with reversible obstructive airway disease, such as asthma.

Albuterol belongs to the family of medicines known as adrenergic bronchodilators. Adrenergic bronchodilators are medicines that open up the bronchial tubes (air passages) in the lungs. They relieve cough, wheezing, shortness of breath, and troubled breathing by increasing the flow of air through the bronchial tubes.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain albuterol. It may not be specific to Brosol Nebules P.F.. Please read with care.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine or any asthma medicine without telling your doctor. To do so may increase the chance for breathing problems.

The albuterol inhalation solution (eg, Accuneb®) should be used with a jet nebulizer that is connected to an air compressor with good air flow. The inhalation solution and nebulizer will come with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

To use the inhalation solution in the nebulizer:

Use one container of solution or mix the exact amount of solution using the dropper provided for each dose. Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine. Connect the nebulizer to the face mask or mouthpiece. Use the face mask or mouthpiece to breathe in the medicine. Use the nebulizer for about 5 to 15 minutes, or until the medicine in the nebulizer cup is gone. Clean all the parts of the nebulizer after each use.

The albuterol inhalation aerosol (eg, ProAir® HFA, Proventil® HFA) and albuterol inhalation powder (eg, ProAir® Digihaler™, ProAir® Respiclick®) are used with a special inhaler that comes with patient instructions. Read the directions carefully before using this medicine. If you or your child do not understand the directions or are not sure how to use the inhaler, ask your doctor to show you what to do. Also, ask your doctor to check regularly how you or your child use the inhaler to make sure you are using it properly.

To use the inhalation aerosol:

The inhaler should be at room temperature before you use it. Insert the metal canister firmly and fully into the actuator. This actuator should not be used with other inhaled medicines. Remove the cap and look at the mouthpiece to make sure it is clean. Point the inhaler away from your face. Shake the inhaler well and test spray it in the air 3 times for ProAir® HFA or 4 times for Proventil® HFA before using it for the first time or if the inhaler has not been used for more than 2 weeks. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece just in front of your mouth with the canister upright. Open your mouth and breathe in slowly and deeply (like yawning), and at the same time firmly press down once on the top of the canister. Hold your breath for about 10 seconds, then breathe out slowly. If you are supposed to use more than one puff, wait 1 minute before inhaling the second puff. Repeat these steps for the second puff, starting with shaking the inhaler. When you have finished all of your doses, rinse your mouth with water and spit the water out. Clean the inhaler mouthpiece at least once a week with warm running water for 30 seconds, and air dry it completely. If you need to use the inhaler before it is completely dry, shake off the excess water, replace the canister, and spray it 2 times in the air away from the face. Use your regular dose. After using the inhaler, wash the mouthpiece again and dry it completely. If the mouthpiece becomes blocked, washing it will help. The Proventil® HFA inhaler has a window that shows the number of doses remaining. This tells you when you are getting low on medicine. The counter will turn red when there are only 20 doses left, to remind you to refill your prescription.

To use the inhalation powder:

Take the inhaler from the foil pouch before you use it for the first time. The inhaler provides about 200 inhalations. The dose counter will change to red when there are "20" doses left. Call your doctor or pharmacist for a refill of prescription or medicine. Make sure the cap is closed before using this medicine. Do not open the cap unless you are going to use it. Hold the inhaler upright as you open the cap fully until you hear a "click". Your inhaler is now ready to use. To inhale this medicine, breathe out fully, trying to get as much air out of the lungs as possible. Put the mouthpiece fully into your mouth and close your lips around it. Breathe in through your mouth as deeply as you can until you have taken a full deep breath. Do not block the vent above the mouthpiece with your lips or fingers. Hold your breath for about 10 seconds or as long as you comfortably can. Remove the inhaler from your mouth and check the dose counter to make sure you received the medicine. Close the cap firmly over the mouthpiece after using the inhaler. Always close the cap after each use. If you are supposed to use more than one puff, repeat these steps for the second puff, starting with opening the cap fully. Do not use a spacer or volume holding chamber together with the ProAir® Digihaler™. Keep the inhaler clean and dry at all times. Do not wash or put any part of the inhaler in water. Replace the ProAir® Digihaler™ if it has been washed or placed in water. If you need to clean the mouthpiece, wipe it gently with a dry cloth or tissue.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation aerosol dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation powder dosage form (inhaler): For treatment or prevention of bronchospasm: Adults and children 4 years of age and older—Two puffs every 4 to 6 hours as needed. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For prevention of exercise-induced bronchospasm: Adults and children 4 years of age and older—Two puffs taken 15 to 30 minutes before exercise. Children younger than 4 years of age—Use and dose must be determined by your child's doctor. For inhalation solution dosage form (used with a nebulizer): For prevention of bronchospasm: Adults and children older than 12 years of age—2.5 milligrams (mg) in the nebulizer 3 or 4 times per day as needed. Children 2 to 12 years of age—0.63 to 1.25 mg in the nebulizer 3 or 4 times per day as needed. Children younger than 2 years of age—Use and dose must be determined by your child's doctor.

Overdose

If you overdose Brosol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Keep the medicine in the foil pouch until you are ready to use it. Store at room temperature, away from heat and direct light. Do not freeze.

Store unopened vials of this medicine at room temperature, away from heat and direct light. Do not freeze. An open vial of medicine must be used right away.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Store Proventil® HFA inhaler with the mouthpiece down.

Throw away the ProAir® Digihaler™ or ProAir® Respiclick® 13 months after opening the foil pouch, when the dose counter reaches "0", or after the expiration date, whichever comes first.

Detailed Brosol dosage information

Side effects

The most common side effects associated with Brosol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of albuterol inhalation aerosol (eg, ProAir® HFA, Proventil® HFA) in children 4 years of age and older, albuterol inhalation powder (eg, ProAir® Digihaler™, ProAir® Respiclick®) in children 4 years of age and older, and albuterol inhalation solution (eg, Accuneb®) in children 2 years of age and older. However, safety and efficacy have not been established for the albuterol inhalation aerosol and albuterol inhalation powder in children younger than 4 years of age, and albuterol inhalation solution in children younger than 2 years of age.

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The apoptotic index in colonocytes of rats fed diet B was higher than that measured in rats fed diet A. nasutus, present in all genotypes collected from the original collection site, but in only two individuals from 34 other M. We conclude that variational regularization allows for an increase in the number of free parameters in our model which enables development of more-advanced parameter reconstruction algorithms. No damage to leads was associated with the oversensing of myopotentials. Here we show that five putative PEX11 genes (OsPEX11-1-5) present in rice genome and each contain three conserved motifs. We retrospectively analyzed the data of 13 patients operated on for a SSS by middle meatal antrostomy, with the aid of neuronavigation in 7 cases. Two clones from each time point had identical V3 region nucleotide sequences, utilized CCR5 but not CXCR4 for cell entry, and had similar reactivities with reference sera. These observations indicate that PLTP may restore the antioxidant potential of plasma LDL at an early stage of the oxidation cascade that subsequently leads to cellular damages. Lastly, with the recent demonstration of StAR being present in the brain, determining if StAR has a role in the synthesis of neurosteroids should prove to be of great importance. In vitro, type I collagen-, type IV collagen-, or laminin-coated 96-well plates were glycated by glucose-phosphate.

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Average levels of attainment in primary and secondary schools in England in 2010 and 2011 are positively associated with changes in average school lunch take up between 2008-2009 and 2010-2011. The aim of this study is to assess the influence of TRG in ypT3 rectal cancer patients who received neoadjuvant chemoradiation. These results indicate that FR172516 has a potent long-lasting antihypertensive effect without activating sympathetic tone by calcium channel-blocking and beta-adrenoceptor-blocking actions. The response to a booster dose of vaccine is instead comparable in both groups. Patients were divided into two groups based on the occurrence (174 patients) or absence (1367 patients) of postoperative intra-abdominal infectious complications. Infections with Chlamydia pneumoniae, Helicobacter pylori or cytomegalovirus and atherosclerosis. Similarly, in hippocampal primary neurons PS distributed in the inner leaflet of plasma membranes of cell body and dendrites, and in the nuclear envelope. Four themes emerged: (i) contribution, (ii) inclusion, (iii) equal opportunity, and (iv) a barrier-free context. Peroral endoscopic myotomy (POEM) has been introduced as a novel endoscopic treatment for achalasia.

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Secondary cultures have now been established using a splenic stromal cell layer overlaid with cells from different lymphoid sites. The crystal structure of the RVP domain sheds light on a putative substrate recognition site involving a conserved loop. The effect of adjunctive brivaracetam on health-related quality of life (HRQoL) was assessed in a post-hoc analysis using pooled data from three randomized, double-blind, placebo-controlled Phase III studies in patients with refractory focal seizures (NCT00490035, NCT00464269, and NCT01261325). Pharmacoeconomic analysis of using mirabegron to treat overactive bladder in the setting of the Russian Federation health care. In addition, the potency of CuE on OS cells growth inhibition was assessed in vivo. Use of vetrazine in naprosyn tablets experimental exclusion of the heart from blood circulation. Four of the five sets of target genes for these individual miRNAs overlap in MYC oncogene.

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The pathological hallmark is the presence of a number of trichilemmomas. Our results showed that CASC2 was significantly downregulated in human GC tissues and cell lines by quantitative RT-PCR. Whole transcriptome microarrays identify long non-coding RNAs associated with cardiac hypertrophy. Implicit beliefs about ideal body image predict body image dissatisfaction. Multi-component reaction systems are particularly valued because several elements of diversity can be introduced in a single transformation thereby expanding the diversity of compound libraries. Selective sacral neuromodulation may fail after fluoroscopically guided lead placement because of malpositioning.

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In NF1 patients, larger left putamen volume and larger total white matter volume were associated with more social problems and poorer executive functioning, larger right amygdala volume with poorer executive functioning and autistic mannerisms, and smaller precentral gyrus gray matter density was associated with more social problems. Serial changes in plasma fibrinogen concentration and fibrinolytic activity in African women on oral contraceptive pills. The crystal packing was controlled by homomeric intermolecular oxime...oxime H-bond interactions for 6 and lamivudine dosing cooperative oxime...N(pyridyl) and CH/pi interactions for 7 and 9. We show that the critical temperature for condensation is lowered at extremely low magnetic fields, when the spin degree of freedom is thermally activated. Subsequent analysis showed that GM-CSF transiently increased MT1-MMP mRNA in endothelial cells in a MEK-dependent mechanism, which led to increased surface levels of MT1-MMP. Rwandan-described challenges related to 4 domains: physical resources, human resources, overall systems support, and communication/language. We conclude that chemically rescued CFTR associates with a specific set of HSP70 family proteins that mark therapeutic interactions and can be useful to correct both ion transport and inflammatory phenotypes in CF subjects. Relative significances of pH and substrate starch level to roles of Streptococcus bovis S1 in rumen acidosis. To test this model, and to map the interface between RecA and its substrates, we carried out alanine-scanning mutagenesis of RecA.

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A prospective multicenter trial evaluating diagnostic validity of multivariate analysis and individual serum marker in differential diagnosis of pancreatic cancer from benign pancreatic diseases. Placental weight and neurologic outcome in the infant: a review. The results are compared with the data obtained invasively during a cardiac catheterization. This article describes a method of in-office fabrication of an occlusal device for treatment of bruxism patients seeking a less costly alternative to laboratory-processed splints. We found that all milk products modulated the invasion of Campylobacter species into the Caco-2 cells in a dose-dependent manner. The polymorphism of the angiotensin II antagonist agent MK-996 was studied, with particular emphasis on crystal form stability, singulair drug action solubility, and reproducible crystallization of the drug.

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