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Brufen (Ibuprofen)

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Brufen works well for treating fever, inflammation, and a variety of mild to moderate pain conditions, but it doesn't last as long as other medications like it. It is available both over-the-counter and at higher strengths with a prescription.

Other names for this medication:
Advil, Answell, Artigesic, Brudex, Bruffen, Brustin, Brutex, Cypaflam, Dexorin, Diclospas, Ibifon, Ibruvon, Ibugard, Ibular, Ibulite, Ibumol, Iburic, Ibuspa, Ibusynth, Ibutos, Infen, Inflapen, Maxofen, Mortrin, Neurophen, Norswel, Nuprin, Nuren, Ospidyne, Proxigesic, Pyrofen, Romet, Rufen, Spinach, Sugafen, Tidifen, Tizafen, Tizapam, Tizidal, Ultraprin

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Also known as: Ibuprofen


Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will help you only as long as you continue to take it .

In addition, ibuprofen can be used to treat fever, menstrual cramps, and other conditions as determined by your doctor .

This medicine is available both over-the-counter (OTC) and with your doctor's prescription .


This section provides information on the proper use of a number of products that contain ibuprofen. It may not be specific to Brufen. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine .

To lessen stomach upset, you may take this medicine with food or milk .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets and suspension): For fever: Children over 2 years of age—Use and dose must be determined by your doctor. Children 6 months of age up to 2 years—Dose is based on body weight and body temperature, and must be determined by your doctor. For fever lower than 102.5 °F (39.2 °C), the dose usually is 5 milligrams (mg) per kilogram (kg) (about 2.2 mg per pound) of body weight. For higher fever, the dose usually is 10 mg per kg (about 4.5 mg per pound) of body weight. The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor . For mild to moderate pain: Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For osteoarthritis and rheumatoid arthritis: Adults and teenagers—1200 milligrams (mg) up to 3200 mg per day divided into three or four equal doses. Children—Dose is based on body weight and must be determined by your doctor. The dose usually is 30 milligrams (mg) to 40 mg per kilogram (kg) of body weight per day, divided into three or four doses. Infants younger than 6 months of age—Use and dose must be determined by your doctor .


If you overdose Brufen and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Brufen overdosage: uncontrolled eye movements, blue color around lips, mouth, and nose, slow breathing, feeling lightheaded.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Brufen dosage information

Side effects

The most common side effects associated with Brufen are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Effect of testosterone replacement therapy on arterial stiffness in older hypogonadal men. Antibiotic resistance spectra of MRSA vary from that of enteric bacteria typically seen in perianal abscesses. Analysis of Dll4 regulation reveals a combinatorial role for Sox and Notch in arterial development. We classified the grades of sensory disturbance in patients with cervical myelopathy into 3 categories in combination with the findings of DSSEPs and the value of Biothesiometer and SW. The present meta-analysis suggests that the STK15 F31I polymorphism is a strong predisposing risk factor for breast cancer, but no significant association existed between the STK15 V57I polymorphism and the risk of breast cancer. Development of neutralizing interferon antibodies after treatment with recombinant interferon-alpha 2b in patients with malignant carcinoid tumors. Nitrotyrosine residues, which are a marker of peroxynitrite formation and action, are found in placental vessels of preeclamptic and diabetic pregnancies, indicating oxidative stress. Our results support that the healing of the edge defects controls both the crystalline order and the growth lifetime. Effectiveness of a Feedback-Based Brief Intervention to Reduce Alcohol Use in Community Substance Use Disorders. This is a safe drug for long-term topical use in this condition.

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