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Brutiz (Ibuprofen)

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Brutiz is a non-steroidal anti-inflammatory drug (NSAID). It blocks proteins in your body that cause pain, swelling, and fever. Brutiz is available both over-the-counter (OTC) and by prescription. The OTC strength is 200 mg, and the prescription strengths include 400 mg, 600 mg, and 800 mg.

Other names for this medication:
Actimol, Addaprin, Arthophen, Avibru, Brutex, Brutiz, Bruzen, Cipgesic, Combidin, Dexorin, Diclospas, Diplodac, Dolgesic, Elbugesic, Febrilix, Flamizone, Ibruvon, Ibubid, Ibuclin, Ibucon, Ibuflamar, Ibulite, Ibuprofen, Iburic, Ibuspa, Ibutos, Ipecee, Lumbril, Mebufen, Methopar, Methoriv, Neurophen, Norswel, Nuprin, Oxydin, Procold, Profon, Proxigesic, Pyrofen, Saleto, Subdu, Tidifen, Tizapam, Treza, Tricofen, Ultraprin, Zupar

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Temovate, Furadantin, Ceclor, Starlix, Ultram, Zyprexa, Albenza

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Also known as: Ibuprofen


Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat mild to moderate pain, and helps to relieve symptoms of arthritis (osteoarthritis, rheumatoid arthritis, or juvenile arthritis), such as inflammation, swelling, stiffness, and joint pain. This medicine does not cure arthritis and will help you only as long as you continue to take it .

In addition, ibuprofen can be used to treat fever, menstrual cramps, and other conditions as determined by your doctor .

This medicine is available both over-the-counter (OTC) and with your doctor's prescription .


This section provides information on the proper use of a number of products that contain ibuprofen. It may not be specific to Brutiz. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients .

When used for severe or continuing arthritis, this medicine must be taken regularly as ordered by your doctor in order for it to help you. This medicine usually begins to work within one week, but in severe cases up to two weeks or even longer may pass before you begin to feel better. Also, several weeks may pass before you feel the full effects of this medicine .

To lessen stomach upset, you may take this medicine with food or milk .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets and suspension): For fever: Children over 2 years of age—Use and dose must be determined by your doctor. Children 6 months of age up to 2 years—Dose is based on body weight and body temperature, and must be determined by your doctor. For fever lower than 102.5 °F (39.2 °C), the dose usually is 5 milligrams (mg) per kilogram (kg) (about 2.2 mg per pound) of body weight. For higher fever, the dose usually is 10 mg per kg (about 4.5 mg per pound) of body weight. The medicine may be given every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For menstrual cramps: Adults—400 milligrams (mg) every four hours, as needed. Children—Use and dose must be determined by your doctor . For mild to moderate pain: Adults and teenagers—400 milligrams (mg) every four to six hours, as needed. Children over 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose usually is 10 milligrams (mg) per kilogram (kg) of body weight every six to eight hours, as needed, up to 40 mg per kg per day. Infants younger than 6 months of age—Use and dose must be determined by your doctor . For osteoarthritis and rheumatoid arthritis: Adults and teenagers—1200 milligrams (mg) up to 3200 mg per day divided into three or four equal doses. Children—Dose is based on body weight and must be determined by your doctor. The dose usually is 30 milligrams (mg) to 40 mg per kilogram (kg) of body weight per day, divided into three or four doses. Infants younger than 6 months of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Brutiz Childrens dosage information

Side effects

The most common side effects associated with Brutiz are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Brutiz if you are allergic to Brutiz components or to aspirin. Try to be careful when use Brutiz while you are pregnant or have nurseling. Brutiz can't be used by patients under 2 years. Do not use Brutiz before or after CABG (heart bypass surgery). Try to be careful with Brutiz in case of using such medication as glyburide (Micronase, DiaBeta); cyclosporine (Gengraf, Neoral, Sandimmune); steroids (prednisone); aspirin or other NSAIDs as naproxen (Aleve, Naprosyn), ibuprofen (Advil, Brutiz), ketoprofen (Orudis), indomethacin (Indocin), diclofenac (Voltaren), etodolac (Lodine); ACE inhibitor as ramipril (Altace), moexipril (Univasc), perindopril (Aceon), enalapril (Vasotec), fosinopril (Monopril), benazepril (Lotensin), quinapril (Accupril), captopril (Capoten), trandolapril (Mavik), lisinopril (Zestril, Prinivil); methotrexate (Rheumatrex, Trexall); diuretics as furosemide (Lasix); lithium (Eskalith, Lithobid); blood thinner as warfarin (Coumadin). Try to be careful with Brutiz in case of having high blood pressure, kidney, heart or liver disease, asthma, congestive heart failure, blood clot, stomach ulcers, stroke, nose polyps, bowel problems, bleeding, diverticulosis. Avoid alcohol. Use Brutiz with great care in case you want to undergo an operation (dental or any other). Try to be careful with Brutiz in case of having phenylketonuria. Try to avoid aspirin usage. Brutiz can be not safety for elderly people. Try to be careful with sunbeams. Brutiz makes skin sensitive to sunlight. Protect skin from the sun. It can be dangerous to stop Brutiz taking suddenly.

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Proteomic profiling was utilized to identify nodal hubs of the Trop-2 cancer growth-driving network. Full implementation of the system on an Nd:yttrium lithium fluoride actively mode-locked laser is presented. Strong CL can also be triggered, and at the same levels, when the various polyelectrolytes are simply mixed with the bacteria or zymosan and added to the leukocyte suspensions. These changes are central not only in the development of atherosclerosis but also in the evolution of both stable and unstable ischemic syndromes. Overexpression of Cbl, but not Cbl-G306E, in Jurkat T cells led to a decrease in the TCR-induced NF-AT luciferase reporter activity. Chronic inflammation in the respiratory system may participate in CNT-induced carcinogenesis. Susceptibility of amphibians to chytridiomycosis is associated with MHC class II conformation.

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Numerous examples of human diseases and model systems suggest that mitochondrial iron homeostasis is coordinated through transcriptional remodeling. Male apical radii were longer than those of females but the p-values were the same. However, increasing GSH levels by overexpression of genes for GSH biosynthesis (GSH1 and GLR1) or by the exogenous addition of GSH to the culture medium enhanced tolerance to furfural but not to HMF. There was little difference in health-adjusted life expectancy between smokers who quit all tobacco and smokers who switch to snus (difference of 0.1-0.3 years for men and 0.1-0.4 years for women). This study did show a modest reduction in some aspects of bowel morbidity when patients had a preoperative bowel preparation before scoliosis surgery.

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Expression of arylamine N-acetyltransferases in pre-term placentas and in human pre-implantation embryos. Inherent physical characteristics and gene expression differences between alveolar and basal bones. However, lymphocytes sensitive to the immunizing antigen and the P2 protein were present. Further significant differences were found in the plasma concentrations of calcium, total lipids, and aldosterone (Table 3), in the somatic indices of fat body and gonads, in the glycogen and protein content of the liver (Table 4), and in the activities of glucose-6-phosphate dehydrogenase, fructose-1,6-diphosphatase, and phosphoenolpyruvate carboxykinase in the liver (Table 5). Women who underwent first trimester screening for chromosomal abnormalities between January and November 2011 were included in the study, and a side effects of tetracycline antibiotics sample of maternal serum was obtained. Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development. The studies reported epigenetic regulation of 34 metabolic genes (involved in fetal growth, glucose and lipid metabolism, inflammation, atherosclerosis and oxidative stress) in blood cells to be related with CVD.

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Characterization of genetic alterations in primary human melanomas carrying BRAF or NRAS mutation. Blood samples were obtained every 6 h to characterize the midcycle LH surge. Alternatively, draining LNC were removed and challenged in vitro with either haptenated protein or haptenated, irradiated, syngeneic spleen cells to induce lymphotoxin (LT) production or proliferation. Experimental evolution of olfactory memory in Drosophila melanogaster. Their advantages and disadvantages are discussed and potential use in biosensing systems, rather than in computing devices, is suggested.

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Subjective symptoms of schizophrenia in research and the clinic: the basic symptom concept. There is limited evidence to support the hypothesis that CHD mortality rates in younger age groups in the member states of the EU have been more likely to plateau than in older age groups. The anonymization guidelines of 13 respected journals were reviewed for adequacy in accordance to facial recognition literature. Commuting routes were modelled based on the shortest street network distance between home and work, with enalapril brand name uk exposure (counts of food outlets) that accounted for travel mode and frequency. Immunological function of monocytes in pregnancy and the puerperium. Characteristics of biochemical processes of the liver in rats with various types of open-field behavior. Effects of crude oil on the air-breathing organs of the striped gourami, Colisa fasciatus: a SEM study. The technical aspects of manual total hip arthroplasty are briefly described. Obesity can act as a significant risk factor in progression of periodontitis.

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