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Glucophage (Metformin)

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Glucophage is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain and is taken by mouth.

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Theolair, Avapro, Arcoxia, Effexor, Zyrtec, Chloromycetin, Periactin, Prevacid

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Also known as: Metformin


{name} (metformin) is an oral diabetes medicine that helps control blood sugar levels.

{name} is used together with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus.

{name} is sometimes used together with insulin or other medications, but metformin is not for treating type 1 diabetes.


Glucophage can be taken in form of pills and extended-release pills which should be taken by mouth. It is better to take Glucophage every day at the same time with meal or without it. Usual Glucophage dosage is taken 2-3 times a day with meals. Glucophage XR (extended-release tablets) is taken once a day with evening meal. Take Glucophage and remember that its dosage depends on patient's health state. Glucophage can't be used by patients under 10 years. Glucophage XR (extended-release tablets) can't be used by patients under 17 years. It can be dangerous to stop Glucophage taking suddenly.


Do not take Glucophage tablets in large quantities. In case of Glucophage overdosage, you need to visit doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Glucophage are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use MetFORMIN (Eqv-Glucophage XR) if you are allergic to it, or if you have:

severe kidney disease; or metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking MetFORMIN (Eqv-Glucophage XR). Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine); high ketone levels in your blood or urine; heart disease, congestive heart failure; liver disease; or if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

MetFORMIN (Eqv-Glucophage XR) may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

MetFORMIN (Eqv-Glucophage XR) should not be given to a child younger than 10 years old. Some forms of MetFORMIN (Eqv-Glucophage XR) are not approved for use by anyone younger than 18 years old.

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Single infection significantly impaired tracheal relaxation to isoproterenol doses from 1.0 X 10(-7) to 5.0 X 10(-4) M, and double infection significantly impaired tissue responses at drug doses from 1.0 X 10(-7) to 1 X 10(-4) M. Highly purified human IFN derived from lymphoblastoid cells (HuIFN alpha-Namalwa) strongly inhibited the growth of a human breast cancer growing as a xenograft in nude mice. The results glucophage 500 mg price in pakistan showed that NP9EO could be rapidly biodegraded under three different reductive conditions. The distribution of motoneurons in the lumbosacral spinal cord of the turtle Pseudemys scripta elegans was studied by using the technique of retrograde transport of horseradish peroxidase. Our study aimed to demonstrate the characteristics of electrical injury in construction workers among one of the largest Iranian population at a burn care hospital. Genetic variation among Mediterranean populations of Sesamia nonagrioides (Lepidoptera: Noctuidae) as revealed by RFLP mtDNA analysis. Fasudil in large doses dilates the neonatal ductus completely, but is associated with fatal side effects, including respiratory depression. Its complexity, together with the appearance of new methods of diagnosis and new alternatives for treatment, mean that the approach to this disease is an important challenge for ophthalmologists.

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Interaction between lumefantrine and monodesbutyl-benflumetol in Plasmodium falciparum in vitro. Various monochloramine concentrations were used, and some animals were pretreated with taurine, a monochloramine scavenger, via the gastrostomy. These findings suggest that NGF signaling may be important in human kidney and glomerular response to injury, though to understand the precise functional significance of these NGF elements in the human kidney, further studies need to be done. Phosphoamino acid analysis revealed that CPTP1 was phosphorylated on both serine and threonine residues by CKII, and tyrosine residue by p56lck. These improvements range from better treatment of local pathologies to improved drug bioavailability and controlled release to enhanced patient compliance. Effects of changing salt and water balance on renal kallikrein, kininogen and kinin. Both public and private hospitals employ standard methods for disposing of healthcare waste. His symptoms resolved and his creatine kinase level dropped down to 256 IU/L 3 weeks after finasteride discontinuation. During the forward digit span, ADHD participants exhibited greater activation of LH linguistic processing areas and increased activation of right frontal and parietal cortices. The study supports the use of DDS to indicate inadequate intakes of micronutrients by breast-fed infants in different seasons.

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Multiparous pregnant women showed positive LAI responses to cancer extracts but not to extracts from normal tissues of the same organ. Characterization of iris pattern stretches and application to the measurement of roll axis eye movements. Computed tomography (CT) generates detailed information on tissue densities, and lung density by CT has the potential of being both more sensitive and specific for monitoring emphysema in clinical trials than more traditional outcome measures such as pulmonary function tests. Nowadays general anesthesia is maintained using as the controller the human intervention, relying only on the quick and certain response of the anesthesiologist to the surrounding conditions, in order to provide the adequate state of anesthesia for the three main components - hypnosis, analgesia and paralysis. Lymphokine production in response to EBV antigens was also initiated during the acute phase. These findings suggest the need to consider strengthening the training related to IPPs as a separate entity in the existing curriculum. We tested the hypothesis that stress responses mediated by the Nrf2-antioxidant responsive element (ARE) pathway are involved in the initiation of retinal neuroprotection provided by bright-cyclic-light rearing. Using the numerical model of Scheutjens and Fleer we investigated, on a self-consistent field level, the equilibrium structure of the neurofilament brush formed by the projection domains of NF-H, NF-M, and NF-L proteins. For this reason, a number of chimeric genes have been developed for recombinant AMP production in prokaryotes.

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