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Leukeran (Chlorambucil)
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Leukeran

Leukeran is a prescription medicine used to treat the symptoms of Chronic Lymphatic (Lymphocytic) Leukemia and Hodgkin’s Lymphoma. Leukeran may be used alone or with other medications. Leukeran belongs to a class of drugs called Antineoplastics, Alkylating.

Other names for this medication:
Chloramax, Chlorambucil

Similar Products:
Aldara, Cipro, Periactin, Colospa, Panadol, Valtrex

Also known as: Chlorambucil

Description

{name} is used to treat several types of cancer, including Hodgkin's disease and certain types of leukemia or lymphoma.

Dosage

You must remain under the care of a doctor while you are using Leukeran.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Leukeran is usually taken for 3 to 6 weeks. Follow your doctor's dosing instructions very carefully.

Leukeran can increase your risk of bleeding or infection. You will need frequent medical tests. Your cancer treatments may be delayed based on the results.

Store Leukeran tablets in the refrigerator.

Detailed Leukeran dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include agitation, fast heartbeats, skin rash, bruising, bleeding gums, nosebleeds, trouble breathing, or signs of infection (fever, chills, weakness).

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Leukeran are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

There haven’t been any interactions reported between Leukeran and other medications, herbs, supplements, or foods.

However, taking Leukeran with other drugs that cause similar side effects may increase your risk of those side effects. And doing so may also make the side effects worse for you. (For more information about the possible side effects of Leukeran, see the section “Leukeran side effects” above.)

To help avoid possible drug interactions, talk with your doctor and pharmacist before starting Leukeran. Tell them about all prescription, over-the-counter, and other drugs you take. Also tell them about any vitamins, herbs, and supplements you use. Sharing this information can help you avoid potential interactions.

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Spiritual/Religious experiences and in-treatment outcome in an inner-city program for heroin and cocaine dependence. For better predicting the occurrence of thrombotic events, an International Prognostic Score of Thrombosis for ET (IPSET-Thrombosis) was recently developed. Are ratings of psychomotor retardation correlated with neuropsychological measurements?. Amino acid limitation induces down-regulation of WNT5a at transcriptional level. Equivalent current dipoles (ECDs) were calculated for epileptic spikes on MEG according to the single dipole model. Outside the CACs solitary endothelial cells occasionally exhibited ring-like formations. However, it is yet to be determined whether the administration of a mucolytic has an effect on the transport rate of antibiotics across the airway epithelial cells. Manipulating construal level in a number of different ways and examining a variety of probability judgments, we found that participants led to adopt a high-level-construal mind-set made lower probability assessments than did those led to adopt a low-level-construal mind-set. The aim of the present study was to assess the sarcopenia prevalence and its association with the functionality in elderly inpatient. Binding of warfarin, phenylbutazone, azapropazone, diazepam, digitoxin and cholic acid.

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Structural and dynamic study of the tetramerization region of non-erythroid alpha-spectrin: a frayed helix revealed by site-directed spin labeling electron paramagnetic resonance. Measurement of multiple intraluminal impedance via esophageal catheter in addition to esophageal pH has enhanced our understanding of GER, although it also did not demonstrate a causal relationship between apnea and GER. The essential clinical features of eight cases of carotidynia are outlined. Assessment of CoW configuration on MRA may be helpful to understand the appearance of unilateral thalamic stroke independent from stroke etiology. Haemodynamic changes in gestational proteinuric hypertension: the effects of rapid volume expansion and vasodilator therapy. The B7 family of immunoregulatory receptors: a comparative and evolutionary perspective. Capillarity ion concentration polarization as spontaneous desalting mechanism.

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Two populations were studied: 55 patients retrospectively and 82 subjects prospectively. The neurodevelopmental hypothesis of schizophrenia suggests that, at least in part, events occurring within the intrauterine or perinatal environment at critical times of brain development underlies emergence of the psychosis observed during adulthood, and brain pathologies that are hypothesized to be from birth. Autogenic repair techniques, including osteochondral plug transplantation, chondrocyte implantation, and microfracture, are the most widely accepted clinical treatment options due to the lack of immunogenic reactions, but only moderate graft success rates have been reported. To determine if there is a variation in the ischemic burden post-acute myocardial infarction (AMI), as assessed by myocardial perfusion imaging (MPI), between different populations in different geographic locations and to see if this variation is associated with different clinical outcomes. The rise in blood sugar in hemorrhagic shock increases with the amount of blood withdrawn per unit of time. Nitroakridin 3582: a fluorescent nitroacridine stain for identifying hypoxic cells. Effects of secondary interactions on the kinetics of peptide and peptide ester hydrolysis by tissue kallikrein and trypsin. Subtotal median sternotomy (SMS) was developed to overcome such limitations. We investigated whether or not the opioid analgesic buprenorphine could be used in rabbits without compromising the myxoma virus virulence assay and on the presumption that animals may suffer pain during the course of the disease. Diagnostic accuracy of shoulder ultrasound performed by a single operator.

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Retrospective analysis of extended gastrectomy and lymphadenectomy in early gastric cancer patients. How prevalent are potentially illegal questions during residency interviews?. Chronic evolution after drug-induced liver injury (DILI) has been reported. It is estimated that approximately 1 out of every 20 hospitalized patients will contract an HCAI. To investigate the possible relationships between plasma bilirubin levels and concentrations of nitric oxide (NO), malondialdehyde (MDA), and erythrocyte antioxidant enzyme activities in newborn infants with hyperbilirubinemia. Here we present two different cases of APS with anopthalmia/microphthalmia, cleft palate, low set ears, ventriculomegaly and one of which had intestinal non-fixation anomaly not described in the literature before.

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Estimating population prevalence of human immunodeficiency virus infection in urban areas with high rates of intravenous drug use: a model of the Bronx in 1988. Unusual cause of obstructive jaundice revealed by endoscopic ultrasound guided fine-needle aspiration of mediastinal lymph node. Non-esterified fatty acids in brush border membrane may thus provide a physiological mechanism of mucosal Fe uptake. Interventions consisting of 8 sessions or more had the greatest treatment efficacy. A cesarean section dehiscence with utero-peritoneal fistula was diagnosed by transvaginal ultrasound. Use of the pneumococcal serovar 3 erythrocyte antibody diagnostic agent for analyzing polysaccharide-containing preparations. After removal of duplicates and review of publications, 6 were deemed relevant. Other assessments did not demonstrate a statistical significance between the two groups.

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Using routine cell stains, the output from fluorescence, Raman and SERRS is quantified at four wavelengths of excitation, demonstrating the potential at longer biologically compatible wavelengths of using nanoparticles with cell stains for superior cell mapping. These strong electrophiles combine covalently and non-enzymatically with nucleophilic sites in DNAs, RNAs, proteins, and small molecules in target tissues. We showed that, unlike mature endothelial cells, CB-ECFCs expressed genes involved in the maintenance of embryonic stem cell properties such as DNMT3B, GDF3 or SOX2. The formation and maturation of the outer epithelial layer is essential for maximal alphafetoprotein (AFP) production during differentiation of F9 embryoid bodies in the presence of 5 X 10(-8) M retinoic acid (Grover et al., 1983. Tight regulation of hematopoietic stem cell (HSC) homeostasis ensures lifelong hematopoiesis and prevents blood cancers.

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The role of HSP70 on ENPP1 expression and insulin-receptor activation. We used four MPM cell lines (MS589, H28, H2052, JMN), a normal mesothelial cell line (HM3), and a lung cancer cell line (H23) in survival studies utilizing bortezomib, cisplatin, and pemetrexed alone and in combination by administering concurrently or by varying the order of administration. Future time perspective and positive health practices among young adolescents: a further extension. The appearance on CT scan may help in distinguishing ameloblastoma from KOT by looking at bone expansion and high density areas, although the gold standard diagnostic test remains open biopsy. The aim of this study was to quantify the medial soft tissue contributions to stability following constrained condylar (CC) total knee arthroplasty (TKA) and determine whether a medial reconstruction could restore stability to a soft tissue-deficient, CC-TKA knee. Correspondingly, the rate of appearance of 3H-dextran in the anaphylactoid target organs such as the footpad was faster in reactive rats, approximately three times as much radioactivity being located in their footpads, 30 min after injection. Nineteen Trisomy 21 patients (17 to 37 years of age) contributed subgingival samples from molar and bicuspid teeth presenting interproximal periodontitis lesions (probing depths, 5 to 8 mm) and from shallow periodontal sites (probing depths, 1 to 3 mm).

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