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Lodine (Etodolac)

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Lodine is used to relieve pain from various conditions. It also reduces pain, swelling, and joint stiffness from arthritis. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body's production of certain natural substances that cause inflammation.

Other names for this medication:
Etios, Etobest, Etodolac, Etofree, Etogesic, Etomax, Etoron, Etosafe, Etova, Etura, Freeup, Penalgon, Proxym, Setolac, Toldin

Similar Products:
Cordarone, Tenormin, Furadantin, Theolair, Intagra

Also known as: Etodolac


{name} (etodolac) is a nonsteroidal anti-inflammatory drug (NSAID). It works by reducing hormones that cause inflammation and pain in the body.

{name} is used to treat mild to moderate pain, osteoarthritis, or rheumatoid arthritis.


This section provides information on the proper use of a number of products that contain etodolac. It may not be specific to Lodine XL. Please read with care.

For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than ordered by your doctor. Taking too much of this medicine may increase the chance of unwanted effects, especially in elderly patients.

This medicine should come with a Medication Guide. It is very important that you read and understand this information. Be sure to ask your doctor about anything you do not understand.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute pain: For oral dosage form (capsules or tablets): Adults—200 to 400 milligrams (mg) every 6 to 8 hours. However, the dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor.

For osteoarthritis and rheumatoid arthritis: For oral dosage form (capsules or tablets): Adults—300 milligrams (mg) 2 to 3 times a day, or 400 or 500 mg 2 times a day. Your doctor may lower your dose to 600 mg once a day. The dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—400 to 1000 milligrams (mg) once a day. Children 6 to 16 years of age—Dose is based on body weight and must be determined by your doctor. Children younger than 6 years of age—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, vomiting, stomach pain, or stomach bleeding.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Lodine XL dosage information

Side effects

The most common side effects associated with Lodine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of etodolac capsules and tablets in the pediatric population and extended-release tablets in children younger than 6 years of age. Safety and efficacy have not been established.

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Deciphering the role of phosphatidylinositol 3-kinase mutations in human epidermal growth factor receptor 2-positive breast cancer. Cases of AMI were identified between 1 January 1993 and 31 December 2000. Traumatic injuries to the rectum although uncommon can result in virulent complications and even death. Photoprotective role of metallothionein in UV-injury - metallothionein-null mouse exhibits reduced tolerance against ultraviolet-B. Prick by prick with fresh pine nuts and RAST with pine nut and pine pollen extracts showed that the patient had high levels of specific IgE against both extracts.

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To investigate the relationship between protein aggregation and cellular toxicity, we have characterized and compared the effects of two GFP-fusion proteins that form aggregates in Saccharomyces cerevisiae, one with a polyasparagine repeat (GFP(N104)) and one without (GFP(C)). In summary, we demonstrated that high-throughput RT-qPCR with pre-amplification step had increased sensitivity cost of zyrtec 10 mg and can be achieved with accuracy and high reproducibility through stringent experimental controls. Asthma management in New York City schools: A classroom teacher perspective. A safe, effective, and easy to use warfarin initiation dosing nomogram for post-joint arthroplasty patients. Identification of human estrogen-inducible transcripts that potentially mediate the apoptotic response in breast cancer. An increase in the percentage of unsaturated fatty acids in heat- or salt-acclimated cells correlated with a decrease in the induction of a general stress-response-promoter-element (STRE)-driven reporter gene by either stress. The decreased expression and activities of early enzymes in the pathway could be explained by a feedback-controlled mechanism in response to lower Mg-chelatase activity. The relationship of anatomical and functional connectivity to resting-state connectivity in primate somatosensory cortex.

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A 1.2-Mb bacterial-artificial-chromosome (BAC)/P1 contig was constructed, bounded by the marker D3S3691 distally and by the gene ATP2B2 proximally. Potential nutraceutical properties of hydrophilic antioxidants in fruits of tomato landraces collected in Andean valleys were characterised. Features of Variable Number of Tandem Repeats in Yersinia pestis and the Development of a Hierarchical Genotyping Scheme. BSN down-regulated STAT3-regulated gene products, inhibited proliferation, invasion, as well as induced apoptosis. The addition of exisulind to a standard regimen of carboplatin and etoposide did not improve outcomes compared with historic controls treated with chemotherapy alone. The selected optimised formulations were compared with marketed preparation for in vivo ocular irritation in healthy rabbits and for in vivo pharmacodynamic efficacy on alpha-chymotrypsin-induced glaucomatous rabbits. Our data show no association between the five evaluated variants and POAG in the Brazilian population. An experimental study is conducted in this paper to evaluate the difference between the ray-driven and pixel-driven implementations of the 3D weighting from the perspective of image quality, while their computational complexity is analyzed theoretically.

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Latex agglutination and indirect hemagglutination tests were insensitive for detection of T gondii antibodies in ovine fetal sera. In addition, dog rods may support the discrimination of flicker at much higher rates than can human rods. PDSS2 was downregulated in poorly differentiated cancer samples compared with well-differentiated tumor samples, and the expression level was markedly lower in HCC tissues than in histologically normal tissue adjacent to the cancer. All lesions presented as multicystic presacral masses and all were surgically resected. When the subjects evaluated puffs of smoke with high and low nicotine content, mecamylamine caused a dose-related decrease in the self-rated strength and harshness of the high nicotine dose level smoke. MRI is not officially incorporated in the International Federation of Gynecology and Obstetrics (FIGO) staging system, but is already widely accepted as the most reliable imaging technique for the diagnosis, staging, treatment planning, and follow-up of both endometrial and cervical cancer. From May 2003 through March 2006, all previously untreated HCV-infected patients were enrolled in this study. An increased accumulation zyloprim 300 mg precio farmacia san pablo of fat in the intraabdominal cavity, termed visceral adiposity, is highly correlated with an adverse coronary risk profile. Patients with leukoaraiosis have a negative prognosis in terms of death, stroke, and myocardial infarction.

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