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Lopressor (Metoprolol)

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Lopressor is a beta-blocker used to treat chest pain (angina), heart failure, and high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This drug works by blocking the action of certain natural chemicals in your body (such as epinephrine) that affect the heart and blood vessels. This lowers heart rate, blood pressure, and strain on the heart.

Other names for this medication:
Actiblok, Actocard, Asoprol, Betaloc, Betaone, Blumeta, Dutoprol, Intramet, Macsart, Mepol, Metapro, Metin, Metocare, Metolar, Metomac, Metozest, Metpure, Metscore, Nexovas, Powermet, Sitelol, Supermet, Telidin, Teliprolol, Toprol, Translol, Vasomet, Vinicor, Vivalol

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Duricef, Lamisil, Albenza, Antabuse, Xalatan

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Also known as: Metoprolol


Metoprolol injection is used to reduce the risk of death from an acute heart attack. It is given to people who have already had a heart attack.

This medicine is a beta-blocker. It works by affecting the response to nerve impulses in certain parts of the body, like the heart. As a result, the heart beats slower and decreases the blood pressure. When the blood pressure is lowered, the amount of blood and oxygen is increased to the heart.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metoprolol. It may not be specific to Lopressor. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Your dose may need to be changed several times in order to find out what works best for you.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of food you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should first check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, strokes, or kidney disease.

Swallow the extended-release capsule and tablet whole. Do not crush, break, or chew them.

If you cannot swallow the extended-release capsule:

You may open it and sprinkle the contents over a small amount (teaspoonful) of soft food (including applesauce, pudding, or yogurt). Swallow the mixture within 60 minutes. Do not store for later use. You may also use a nasogastric tube to give the medicine. Mix the contents of the opened capsule with water into a syringe. Gently shake the mixture for about 10 seconds, then flush it through the tube. Rinse the tube with water until all of the medicine is washed out.

Take the tablet or extended-release tablet with a meal or just after you eat. You may break the extended-release tablet into two pieces, but swallow the two pieces whole and do not crush or chew them.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For acute heart attack or heart failure: For oral dosage form (extended-release capsules): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. Your doctor may adjust your dose as needed. However, the dose is usually not more than 200 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 milligrams (mg) once a day for 2 weeks. In patients with severe heart failure, the starting dose is 12.5 mg once a day. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 50 milligrams (mg) every 6 hours for 2 days. Then, 100 mg 2 times a day. The medicine will be started in the hospital. Children—Use and dose must be determined by your doctor. For chest pain: For oral dosage form (extended-release capsules): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given in two divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children—Use and dose must be determined by your doctor. For high blood pressure: For oral dosage form (extended-release capsules): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight once a day. The first dose should not be more than 50 mg once a day. Your doctor may adjust your dose as needed. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 25 to 100 milligrams (mg) once a day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 400 mg per day. Children 6 years of age and older—Dose is based on body weight and must be determined by your doctor. The dose is usually 1 milligram (mg) per kilogram (kg) of body weight per day, given as a single dose. The first dose should not be more than 50 mg per day. Children younger than 6 years of age—Use and dose must be determined by your doctor. For oral dosage form (tablets): Adults—At first, 100 milligrams (mg) per day, given as a single dose or in divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 450 mg per day. Children—Use and dose must be determined by your doctor. .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heart rate, trouble breathing, or fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Lopressor dosage information

Side effects

The most common side effects associated with Lopressor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Gd-EOB-DTPA-Enhanced MR Imaging of the Liver: The Effect on T2 Relaxation Times and Apparent Diffusion Coefficient (ADC). Completion of the mitochondrial genome sequence of onion (Allium cepa L.) containing the CMS-S male-sterile cytoplasm and identification of an independent event of the ccmF N gene split. Current-induced effects on growth and adhesion properties of Streptococcus mutans in vitro. Reduced expression of muscle-specific microRNA (myomiRs) in quadriceps muscle in patients with COPD is associated with skeletal muscle weakness and changes in muscle fibre composition. Using SNPlex application and corroboration from the sequencing analysis, the informativeness of SNP markers from the heterozygous grape cultivar Pinot Noir was validated in V.

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For patients with severe, refractory disease, methotrexate may be most effective while cyclosporine may be most valuable for patients needing rapid, short-term improvement. Acutely, both 1 and 5 mg/kg propranolol immediately decreased heart rate (HR) and cardiac output (CO). Clinical practice guidelines, technology assessments, systematic reviews and randomized controlled trials addressing systemic therapy for women with recurrent ovarian cancer were eligible. As activation of the ETB receptor has an opposing effect, inducing cell death by apoptosis, a rationale exists for specific antagonism of the ETA receptor as a treatment strategy for cancer. Novel TGFBI mutation p.(Leu558Arg) in a lattice corneal dystrophy patient.

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RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. The neurons responded to more than one kind of noxious stimuli by increasing or decreasing its firing rate. Routine Coronary Arteriography Following Thrombolytic Therapy for Acute Myocardial Infarction: An Unsettled Controversy. These cases should be thoroughly studied so that patients may be accurately informed of the recurrence risk. This study assessed differences in beliefs (from the Health Belief Model) by stage of screening behavior adoption (based on the Transtheoretical Model of Change) as a foundation for intervention development. The aim of the present study is to produce standards of weight for age and to analyse the effects of seasonal variation and of infectious disease on the rate of growth in weight of Central African babies. They can also be signs of emotional, social, family and behavioral problems. Cellular genes that are homologous to the transforming genes of certain RNA tumor viruses are suspected to play a functional role during normal developmental processes.

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Immune-related late-onset how much does lipitor cost without insurance hemorrhagic cystitis post allogeneic hematopoietic stem cell transplantation. Our aim was to investigate whether a nasopharyngeal sample, obtained in routine medical practice, could yield information about the aetiology of a long-standing cough in patients with a respiratory tract infection. These services include drinking water supply (DWS), wastewater and sewage treatment (WST), and municipal solid waste management (MSW). These studies demonstrate that high levels of arsenic may inhibit NF-kappaB-mediated gene transcription by specifically blocking IKK activity, thereby limiting the phosphorylation and subsequent degradation of the NF-kappaB inhibitor, IkappaBalpha. This heterogeneity generated by reconstitution post secretion must be considered in studies of populations of mast cells in vivo. aureus (MRSA) infections, knowing the resistance to these antibiotics is imperative.

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Purified free canine cTnI was diluted to 5 known concentrations to assess linearity and recovery. The chronic pathological changes in vascular walls of hypertension may exert destructive effects on multiple organ systems. Risky driving and hazardous drinking are associated with significant human and economic costs. Furthermore, risedronate/ZnHA drug formulation showed higher values of calcium/phosphorous ratio and zinc content. Cell lines derived from central nervous system atypical teratoid rhabdoid tumor (AT/RT) (BT12, BT16 and KCCF1), sarcoma (143B, HOS, RD and RH30), and neuroblastoma (SKNAS, SKNBE2, IMR-5 and IMR-32) were examined for vvDD mediated cytotoxicity defined by virus expansion followed by loss of tumor cell viability. Careful assessment for the need for intubation should be emphasized. Diffusion coefficient of salicylic acid (SA) and gatifloxacin, a fourth generation fluoroquinolone, through the membrane was determined.

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Beta-catenin can function as an oncogene when it is translocated to the nucleus, binds to T cell factor or lymphoid enhancer factor family members, and transactivates its target genes. Mutation of F239, which together can you overdose on glucophage with F126 is thought to form an extracytosolic gate to the conductance channel, abolished both ammonium uptake and Mep2p-dependent filament formation, despite proper localization of the protein. Flattened Golgi saccules or early eosinophils stained weakly or not at all with the PA-TCH-SP method. The lactic acid, glucose, and tumor necrosis factor alpha contents in the priming solution and perioperative blood samples were significantly lower in the PZM group compared with the CM group. Pancreatitis-associated protein inhibits human pancreatic stellate cell MMP-1 and -2, TIMP-1 and -2 secretion and RECK expression. High macrophage-colony stimulating factor levels in synovial fluid of loose artificial hip joints. Although the revisions have largely corrected the shortcomings of the 1985 version, some controversies persist. We identified previously unreported VC underdosing in over two-thirds of our patients, with most of these patients having volumes of undistended VC that received less than half of the prescription dose.

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The amplitude spectra are approximated by power law functions and their parameters are read as an underlying signature of the system dynamics. The alphavirus Sindbis virus (SINV) causes encephalomyelitis in mice by infecting neurons of the brain and spinal cord. Study of the role of nuclear factor-kappa B in preterm birth with subclinical chorioamnionitis. Resting UES pressure was analyzed up to 5 min before 10 5-ml water swallows. Five patients received immunosuppressive therapy: cyclophosphamide (two patients), methotrexate (two patients), azathioprine (one patient), mycophenolate mofetyl (one patient), with an inconstant benefit.

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Determination of silencing potency of synthetic and RNase III-generated siRNA using a secreted luciferase assay. A potent uveitopathogenic agent for the induction of experimental autoimmune uveitis. These results taken together suggest that YGGFMRF released in the perfusate of the arachnoidal space by substance P is metabolized by both dipeptidyl carboxypeptidase and aminopeptidase. These properties can positively or negatively influence the vascular system. PAF receptor (PAFR) may be expressed on cellular and nuclear membranes of various cell types, especially leukocytes, platelets, endothelial cells, neuronal cells and microglia. This report aims to feldene mg review the available evidence concerning the use of second-generation antipsychotics depot in bipolar disorder and specify the typology of patients that could be eligible for this formulation. High prevalence of gluten sensitivity in a cohort of patients with undifferentiated connective tissue disease. This subtype of diabetes is characterized by maternal transmission, young age at onset and bilateral hearing impairment. A roundtable discussion: elevating the value and importance of risk management in healthcare technology. Research progress on carbon sink function of agroforestry system under climate change.

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