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Plavix (Clopidogrel)
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Plavix

Plavix is an antiplatelet medication. It works by preventing platelets from sticking together, thereby decreasing the formation of harmful blood clots. This lowers the chance of heart attack or stroke.

Other names for this medication:
Anticog, Antiplar, Antiplatt, Aptogrel, Asicom, Asogrel, Atormac, Cenoza, Clodrel, Clopigrel, Clopitab, Clopivas, Clopiwa, Clotnil, Compivas, Deplatt, Grelet, Kabitrol, Locric, Orawis, Pidgrel, Platfree, Plodrel, Psygrel, Rozanex, Thinrin, Welgrel, Zeter, Zoclop

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Also known as: Clopidogrel

Description

{name} (clopidogrel) prevents platelets in your blood from sticking together to form an unwanted blood clot that could block an artery.

{name} is used to lower your risk of having a stroke, blood clot, or serious heart problem after you've had a heart attack, severe chest pain (angina), or circulation problems.

Dosage

Usual Adult Dose for Acute Coronary Syndrome:

Unstable Angina (UA)/Non-ST-Elevation Myocardial Infarction (NSTEMI): -Loading dose: 300 mg orally once -Maintenance dose: 75 mg orally once a day -Duration of therapy: Optimal duration unknown. ST-Elevation Myocardial Infarction (STEMI): -Loading dose: 300 mg orally once (OPTIONAL) -Maintenance dose: 75 mg orally once a day, with or without thrombolytics -Duration of therapy: Optimal duration unknown. Comments: -Administer this drug in combination with aspirin 75 mg to 325 mg orally once a day. -The benefit of this drug for patients who undergo primary percutaneous coronary intervention is unknown. Uses: Prevention of atherothrombotic events in patients with non-ST-segment elevation acute coronary syndrome (UA, NSTEMI, those who are to be managed medically, those who are to be managed with coronary revascularization) and STEMI.

Usual Adult Dose for Ischemic Stroke:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Myocardial Infarction:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Usual Adult Dose for Peripheral Arterial Disease:

75 mg orally once a day Uses: Prevention of atherothrombotic events in patients with a history of recent myocardial infarction, recent stroke, or established peripheral arterial disease.

Detailed Plavix dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose can cause excessive bleeding.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Plavix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Plavix if you are allergic to Plavix components. Do not take Plavix if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Plavix if you suffer from or have a history of stroke, stomach ulcer or ulcerative colitis; liver or kidney disease, hemophilia. Be careful with Plavix if you are taking such medicines as aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs such as naproxen (Aleve, Naprosyn), diclofenac (Voltaren), diflunisal (Dolobid), etodolac (Lodine), flurbiprofen (Ansaid), indomethacin (Indocin), ibuprofen (Motrin, Advil), (Toradol), ketoprofen (Orudis), nabumetone (Relafen), piroxicam (Feldene), ketorolac mefenamic acid (Ponstel), meloxicam (Mobic) and the others), phenytoin (such as Dilantin); torsemide (such as Demadex); medication used to prevent blood clots (alteplase (such as Activase), anistreplase (such as Eminase), dipyridamole (such as Persantine), streptokinase (such as Kabikinase, Streptase), ticlopidine (Ticlid) and urokinase (such as Abbokinase); fluvastatin (such as Lescol); a blood thinner (warfarin (such as Coumadin), heparin, ardeparin (such as Normiflo), dalteparin (such as Fragmin), danaparoid (such as Orgaran), enoxaparin (such as Lovenox), or tinzaparin (such as Innohep); tamoxifen (such as Nolvadex); tolbutamide (such as Orinase). It is not recommended to do sport while taking Plavix because it can cause bleeding or bruising injury. If you are going to have a surgery you should stop taking Plavix for 5 days before the surgery. Do not use potassium supplements or salt substitutes. If you want to achieve most effective results without any side effects it is better to avoid alcohol. Do not stop taking Plavix suddenly.

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Defective decapentaplegic signaling results in heart overgrowth and reduced cardiac output in Drosophila. The induction of tachycardia was dependent on a critical AH interval. We can postulate that nafoxidine induces an increase in TIMP-1, which has antiangiogenic activity in the late stages of tube formation, independent of its capacity to inhibit MMPs. The most prevalent form of HF in Galicia was HF with preserved systolic function, which was mostly associated with high blood pressure due to poor control. The analysis of the overall genomic pattern, which probably unravels particular genomic instability mechanisms rather than the analysis of individual markers, is essential to predict relapse in NB patients. Catalytic oxidative cleavage of catechol by a non-heme iron(III) complex as a green route to dimethyl adipate.

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Primary cultures of Kupffer cells have a very limited life span, tend to de-differentiate and become senescent, and therefore are not suitable for cell signaling studies. The results showed that AIT-082 not only effectively inhibited the tremor induced by arecoline or oxotremorine, but also alleviated the tremor intensity and significantly shortened the tremor durations. 3DAP analysis of (Ga,Mn)As diluted magnetic semiconductor thin film. More recent literature suggests that infants with apparent life-threatening events frequently present without signs or symptoms of illness. Transient expression of an AtOCT1::GFP fusion protein in onion epidermal cells and Arabidopsis protoplasts supported localization in the plasmalemma. Validation of the Chinese Version of the Cognitive Symptom Checklist-Work-21 in Breast Cancer Survivors.

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The aim of our prospective designed study was to confirm the intra-observer agreement of assessments of the hydronephrosis index (HI) with a sonographic technique that potentially provides additional information in patients with acute renal colic (ARC). Subsequently, skin biopsies were analysed (immuno) histologically over 10 days, for expression of IFNalpha-induced MxA, numbers of plasmacytoid dendritic cells (pDC), and expression of endothelial cell adhesion molecules, namely E-selectin, ICAM-1, and L-selectin ligand. Is recipient priming with graft foreign antigen a prerequisite for the blood transfusion effect?. Within 62 days of diagnosis, decreasing waiting times from diagnosis to surgery had little impact on survival from localised breast cancer. Hybrid-PLEMO is zopiclone type of drug a compact, low-cost rehabilitation system for upper limbs with high safety by using ER brakes or ER actuators. Cells stably underexpressing calreticulin had elevated expression of calmodulin, activated CaMK II, activated ERK and activated c-src. The major findings are the relative robustness over time of the parameters which characterize the distribution of birthweight within countries, and the marked and consistent differences between these distributions in different countries. To study the effects of systemic inflammatory response syndrome (SIRS) on polymorhonuclear neutrophil (PMN) function and phenotype by comparing neutrophils from critically ill patients with SIRS against those from healthy blood donors.

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We describe a case of cutaneous leishmaniasis with lymphadenopathy due to Leishmania donovani, which was successfully treated with oral miltefosine. To understand how these factors induce pluripotency, we carried out genome-wide analyses of their promoter binding and expression in iPS and partially reprogrammed cells. Therefore, we aimed to investigate the clinicopathological significance of miR-431 in HCC. Hypothalamic pathways involved in what do generic zyrtec pills look like metabolic regulatory functions, as identified by track-tracing methods. Although many investigators reported the diagnostic and therapeutic value of bronchoscopy in the early stage of inhalation injury, few findings in the late stage of inhalation injury have been reported.

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This suggests that interferon itself may not be the cause of general symptoms during a virus illness. Development and characterization of recombinant antibody fragments that recognize and neutralize in vitro Stx2 toxin from Shiga toxin-producing Escherichia coli. These findings correlate the clinical observation of an increased incidence of multisystem injury, including adult respiratory distress syndrome (ARDS), after cryoablation but not RFA. IMGN901 has anti-tumor activity against some CD56 expressing pediatric cancer models. New colored and fluorescent amine substrates for activated fibrin stabilizing factor (Factor XIIIa) and for transglutaminase. Compared to citrate-capped AuNPs, Tween 20-capped AuNPs exhibit the ability to disperse in a highly saline solution and selectively extract aminothiols through the formation of Au-S bonds. Cultivation from the auto-inoculation after the 48 hours was positive for herpes simplex virus type 2. The respirometer signal controls the two membrane pumps and delivers the respiration volume. One-day post-exposure to quartz, elevations in biomarkers of cytotoxicity in BALf, increases in lung and tracheobronchial lymph node weight and histopathological lung changes were minimal.

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Many compounds showed equal affinity for both alpha(1a) and alpha(1d) subtypes with good selectivity versus the alpha(1b) subtype. sp J were found in the warmer localities at 1,010 m-1,280 m altitudes. Both the organization and cellular composition of the RMS and the differentiation of the newly generated neurons in the OB were studied using specific markers of glial cells, neuroblasts, and mature neurons. 1-Amido-1-phenyl-3-piperidinylbutanes - CCR5 antagonists for the treatment of HIV. Clinical evaluation of trimethoprim-containing ophthalmic solutions in humans.

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To prospectively evaluate the long-term impact of valproate (VPA) versus carbamazepine (CBZ) on anthropometric, hormonal, and metabolic parameters in young male patients treated for epilepsy. Taken together, the present results suggest that by binding to P0 through its tail domain and by using its motor activity, KIF4 is involved in the anterograde trafficking of ribosomal constituents to axons and that by means of its Ezrin-Radixin-Moesin-like domain interacts and transports L1. This case report describes a unique variant of a duodenal duplication cyst in an 8-year-old boy who had recurrent episodes of upper abdominal pain. Oxygenation parameters and hypoxemia improved rapidly after treatment. Acoustic dysfunction and microcirculation in patients with diabetes mellitus. A Multicenter, Rater-Blinded, Randomized Controlled Study of Auditory Processing-Focused Cognitive Remediation Combined With Open-Label Lurasidone in Patients With Schizophrenia and Schizoaffective Disorder. Risk factors for non-curative resection of early gastric neoplasms with endoscopic submucosal dissection: Analysis of 1,123 lesions. The clinical findings of 37 eyes with ocular syphilis demonstrated a broad spectrum of clinical manifestations.

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