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Prometrium (Progesterone)

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Prometrium is a natural female sex hormone, progesterone. It is used to treat menstrual and pregnancy-related issues that are caused due to hormonal imbalance. Prometrium is also prescribed along with estrogen as a part of hormonal replacement therapy for preventing endometrial hyperplasia (thickening of the lining of the uterus).

Other names for this medication:
Algest, Belgest, Corion, Crinone, Cygest, Durbagest, Durogest, Egeria, Endogest, Endometrin, Evagest, Gemgest, Gestmate, Gestorin, Gestovin, Hilgestrone, Lutacare, Lutamax, Macgest, Minagest, Miprogen, Namgem, Naturone, Nidagen, Npton, Ornapro, Pgfast, Powergest, Preglon, Pregzed, Progesterone, Promyzz, Rigest, Rimgest, Strone, Sugest, Theragest, Truegest, Vageston

Similar Products:
Omnicef, Ultram, Zyprexa, Aygestin, Prilosec, Lioresal, Thorazine, Duphaston

Also known as: Progesterone


Progesterone is used to help prevent changes in the uterus (womb) in women who are taking conjugated estrogens after menopause. It is also used to properly regulate the menstrual cycle and treat unusual stopping of menstrual periods (amenorrhea) in women who are still menstruating.

This medicine is available only with your doctor's prescription.


Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Take the Prometrium capsule with a full glass of water. It is best to take the medicine at night because this medicine can make you dizzy or drowsy.

Apply Prometrium cream to the skin as directed by your doctor.

Prometrium is sometimes used for only a short time, such as 10 to 12 days during each menstrual cycle. Follow your doctor's dosing instructions very carefully.

Have regular physical exams and self-examine your breasts for lumps on a monthly basis while using Prometrium.

If you need surgery or medical tests or if you will be on bed rest, you may need to stop using this medicine for a short time. Any doctor or surgeon who treats you should know that you are using Prometrium.

Store at room temperature away from moisture, heat, and light.

Detailed Prometrium dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Prometrium dosage information

Side effects

The most common side effects associated with Prometrium are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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