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Sustiva (Efavirenz)
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Sustiva

Sustiva belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It helps to control HIV infection so your immune system can work better.

Other names for this medication:
Cytocom, Duovir, Efavir, Efavirenz, Efcure, Efferven, Emduo, Estiva, Evirenz, Lamivir, Lazid, Odivir, Retrodel, Revenz, Tenola, Trioday, Trustiva, Viraday, Viranz, Virocmb, Virolis, Vonavir, Zidolam

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Also known as: Efavirenz

Description

Sustiva is used to treat HIV infection in combination with other anti-HIV medications. If Sustiva is the only drug you take to treat HIV infection, it may stop working. Sustiva is an oral medication that is used for the treatment of infections with the human immunodeficiency virus (HIV). It is similar to nevirapine (Viramune) and delavirdine (Rescriptor). Sustiva is also known as Efavirenz, Stocrin. Sustiva is in a class of drugs called reverse transcriptase inhibitors which also includes zalcitabine (Hivid), zidovudine (Retrovir), didanosine (Videx), and lamivudine (Epivir). During infection with HIV, the HIV virus multiplies within the body's cells. The newly-formed viruses then are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection continually spreads to new, uninfected cells that the body is continually producing, and HIV infection is perpetuated. When producing new viruses, the HIV virus must manufacture new DNA for each virus. Reverse transcriptase is the enzyme that the virus uses to form this new DNA. Sustiva directly inhibits the activity of reverse transcriptase and blocks the production of DNA and new viruses. Unlike zidovudine, efavirenz does not need to be converted to an active form. Sustiva does not kill existing HIV virus and it is not a cure for HIV.

Dosage

Take this drug by mouth, generally once daily as directed. Take on an empty stomach with a glass of water. Taking Sustiva with food, especially a high-fat meal can lead to increased blood levels of the drug and increase your risk of having side effects. Best taken at bedtime during the first month of use. Using this drug regularly at bedtime may decrease certain side effects. Use this medication regularly in order to get the most benefit from it. To help you remember, use it at the same time each day. Do not take more or less of this drug than prescribed, or stop taking it unless directed to do so by your doctor. Read the patient information leaflet provided by your pharmacist. If you want to achieve most effective results do not stop taking Sustiva suddenly.

Overdose

If you overdose Sustiva and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Sustiva are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired.

Drinking alcohol can increase certain side effects of efavirenz.

Using this medicine will not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.

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