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Trandate (Labetalol)
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Trandate

Trandate is an alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome. Trandate injections are indicated to control blood pressure in severe hypertension. Trandate tablets are indicated alone or in combination with antihypertensives like thiazides and loop diuretics to manage hypertension.

Other names for this medication:
Albetol, Ascool, Biascor, Hybloc, Ibidomide, Ipolab, Labetalol, Labetaloli, Labetalolo, Labetalolum, Normadate, Normodyne, Normozide, Presolol, Resporito

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Also known as: Labetalol

Description

Trandate is a drug which is used for treating high blood pressure. It is related to carvedilol (Coreg). Nerves that are part of the adrenergic nervous system travel to most arteries where they release an adrenergic chemical norepinephrine. The norepinephrine attaches to receptors on the muscles of the arteries and causes the muscles to contract, narrowing the arteries, and increasing the blood pressure. Trandate blocks receptors of the adrenergic nervous system. When Trandate attaches to and blocks the receptors, the arterial muscles relax, and the arteries expand, resulting in a fall in blood pressure. Generic name of Trandate is Labetalol. Trandate is also known as Labetalol, Normodyne. Brand name of Trandate is Trandate.

Dosage

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

Trandate oral is taken by mouth.

Trandate injection is given in a vein by a healthcare provider when hypertension is severe. After the injection you may need to remain lying down for up to 3 hours. You may feel light-headed when you first stand up.

Your blood pressure will need to be checked often, and you may need other medical tests. If you have diabetes, check your blood sugar regularly.

Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms.

Trandate can cause false results with certain lab tests of the urine, including a drug-screening urine test. Tell the laboratory staff that you use this medicine.

Tell your doctor if you have a planned surgery.

You should not stop using Trandate suddenly. Stopping suddenly may make your condition worse.

Store at room temperature away from moisture and heat.

Detailed Trandate dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include slow heart rate, wheezing, chest tightness, trouble breathing, extreme dizziness, seizure, or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Trandate are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use Trandate if you are allergic to it, or if you have:

asthma; "AV block" (2nd or 3rd degree); uncontrolled heart failure; very low blood pressure; slow heartbeats that have caused you to faint; or if your heart cannot pump blood properly.

Tell your doctor if you have ever had:

congestive heart failure; angina (chest pain); liver disease; emphysema, chronic bronchitis, or other breathing problems; pheochromocytoma (tumor of the adrenal gland); diabetes; coronary artery bypass surgery (sometimes called "CABG"); kidney disease; or allergies.

Trandate can affect your pupils. If you need eye surgery, tell the surgeon about your use of Trandate, even if you no longer take it.

Trandate may cause low blood pressure, low blood sugar, slow heartbeats, or breathing problems in a newborn if the mother uses this medicine during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using this medicine.

Not approved for use by anyone younger than 18 years old.

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