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Wellbutrin (Bupropion)

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Wellbutrin is a norepinephrine and dopamine reuptake inhibitor used in the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation. Wellbutrin is indicated for the treatment of major depressive disorder (MDD), seasonal affective disorder (SAD), and as an aid to smoking cessation.

Other names for this medication:
Aplenzin, Budeprion, Bupdep, Bupraset, Bupron, Bupropion, Ession, Nicotex, Smoquit, Unidep, Zyban

Similar Products:
Seroquel, Precose, Feldene, Azulfidine, Risperdal, Nizoral, Aricept, Colospa

Also known as: Bupropion


{name} XL is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.


Take Wellbutrin exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Too much of this medicine can increase your risk of a seizure.

Do not crush, chew, or break an extended-release tablet. Swallow it whole.

You should not change your dose or stop using Wellbutrin suddenly, unless you have a seizure while taking this medicine. Stopping suddenly can cause unpleasant withdrawal symptoms.

Do not stop using Wellbutrin suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using this medicine.

Some people taking Wellbutrin have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum). Your blood pressure may need to be checked before and during treatment with bupropion.

This medicine can cause you to have a false positive drug screening test. If you provide a urine sample for drug screening, tell the laboratory staff that you are taking bupropion.

Store at room temperature away from moisture and heat.

Detailed Wellbutrin dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of Wellbutrin XL can be fatal. Overdose symptoms may include muscle stiffness, hallucinations, fast or uneven heartbeat, shallow breathing, or fainting.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Wellbutrin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use Wellbutrin if you have used an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others.

You should not take Wellbutrin if you are allergic to bupropion, or if you have:

a seizure disorder; an eating disorder such as anorexia or bulimia; or if you have suddenly stopped using alcohol, seizure medications, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).

Do not use an MAO inhibitor within 14 days before or 14 days after you take bupropion. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Do not take Wellbutrin to treat more than one condition at a time. If you take bupropion for depression, do not also take this medicine to quit smoking.

Wellbutrin may cause seizures, especially if you have certain medical conditions or use certain drugs. Tell your doctor about all of your medical conditions and the drugs you use.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

a head injury, seizures, or brain or spinal cord tumor; narrow-angle glaucoma; heart disease, high blood pressure, or a heart attack; diabetes; kidney or liver disease (especially cirrhosis); or depression, bipolar disorder or other mental illness; or if you drink alcohol.

Some young people have thoughts about suicide when first taking an antidepressant. Your doctor will need to check your progress at regular visits while you are using Wellbutrin. Your family or other caregivers should also be alert to changes in your mood or symptoms.

Ask your doctor about taking Wellbutrin if you are pregnant. It is not known whether bupropion will harm an unborn baby. However, you may have a relapse of depression if you stop taking your antidepressant. Tell your doctor right away if you become pregnant. Do not start or stop taking bupropion without your doctor's advice.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of bupropion on the baby.

It may not be safe to breastfeed while using Wellbutrin. Ask your doctor about any risk.

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Fractionated opiate withdrawal with tiapride and naloxone, a new treatment approach. This study was conducted to estimate the prevalence of smoking among pregnant women living in Japan and to analyze the factors associated with their smoking behavior. We assessed the accuracy of self-collected human papillomavirus (HPV) specimens in men compared with clinician-collected specimens from men in British Columbia and determined the prevalence of HPV subtypes at different male genital sites. The nematode, Caenorhabditis elegans, has become an expedient model for studying neurotransmission. Frontal bandeau reconstruction with a fibula flap in a patient with Freeman-Sheldon syndrome. We reviewed clinical data from 217 patients with advanced BTA who were treated with S-1 monotherapy between August 2004 and September 2007. The subjects were evaluated by each threshold strategy on two separate sessions within 14 days in a randomized block design.

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The threat of hospital-acquired infections persists despite advances in the health care system. A versatile multivariate image analysis pipeline reveals features of Xenopus extract spindles. Patients with SD reported that their vocal dysfunction caused a significant negative effect on work productivity and increase in activity impairment. To maximize the chances of success and minimize the possibility of unintended consequences, the appropriate culture and structure of our health care institutions first must be in place. Review of the factors affecting bioavailability of soy isoflavones in humans. Ascitic fluids from patients with congestive heart failure showed no suppressive effects. Times from activation of the aeromedical team to arrival in the emergency department and the operating room for patients with liver or spleen injury were analysed to identify factors that delayed laparotomy. Peritoneal seeding was not found and peritoneal washing cytology was negative. This initial event requires recognition of the junction between the stem and the flanking single-stranded RNA of the pri-miRNA hairpin by DGCR8 followed by recruitment of DROSHA, which cleaves the RNA duplex to yield the pre-miRNA product. The accumulated burden of migraine caused slight alterations in the physiology of the visual cortex.

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Cytokine-mediated inflammation and coagulopathy may occur after cardiac surgery. Individual client care and public health policy: the dual challenges for public health nurses. aeruginosa, and blocking of RSV with heparin eliminated the effect on increased adherence. Experiments are conducted for PP and PE sheets with different thicknesses. Time series analysis has been shown to provide a useful, readily available tool for predicting emergency department workload that can be used to plan staff roster and resource planning.

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We conclude that understanding seagrass meadows as a coupled social-ecological system is crucial in carving pathways for social and ecological resilience in light of current patterns of local to global environmental change. The recognition performance using LDA of IC features has been compared to other approaches including Principle Component Analysis (PCA), LDA of PC, and ICA. Additionally, distalization and expansion of the other teeth and the degrees of molar rotation were measured in group PH and group TD and compared between the two groups. In some types of skin diseases (pustulosis palmaris et plantaris and atopic eczema) an improvement could be demonstrated during the fast. The limiting effect of PI3K on TNF-alpha production from activated monocytes depended on the decrease of GSK-3beta activity, which significantly reduced the transactivation of NF-kappaB. Diagnosis of infection is usually based on an in-practice ELISA for faecal antigen or zinc sulphate flotation of several pooled faecal samples. These results demonstrate that CBG induces a dose-related inhibition of PRL secretion in normal women as well as in puerperal and hyperprolactinemic women. Costs were estimated using data from Medicare, the US Bureau of Labor Statistics, and the Nationwide Inpatient Sample.

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This study found a strong association of change in pain severity and physical functioning with change in baseline level of affective health and coping during the first outpatient management period after inpatient rehabilitation. By screening NDI patients for mutations within the AVPR2 gene we have identified three novel (I46K, F105V, I130F) and four recurrent (D85N, R106C, R113W, Q225X) mutations. Biomimetic MRI contrast agent for imaging of inflammation in atherosclerotic plaque of ApoE-/- mice: a pilot study. Ambulation after femoral sheath removal in percutaneous coronary intervention: a prospective comparison of early vs. Biomantling and bioturbation by colonies of the Florida harvester ant, Pogonomyrmex badius.

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Two new Daphniphyllum alkaloids from the stems and leaves of Daphniphyllum calycinum. This led to the development of USDA Human Nutrition Research Centers at Universities. Electrical probe characteristic recovery by measuring only one time-dependent parameter. As long as the mobility of the fixed bridge does not increase and the patient can function and feel comfortable with it, a successful therapy can be concluded. We establish the unique marker database for human and rat gene index databases using the hash table algorithm. Our results show that, while levels of mRNA correlate with patterns of TNF-alpha and TNF-beta secretion by lymphocytes and macrophages, the transcriptional levels of the corresponding genes do not. The findings with respect to S100 protein favor a neural (Schwann cell) origin of the adult granular cell tumor, but not the congenital form.

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Kinetic method of determining urea concentration in biological media. Spatio-temporal upwelling trends along the Canary Upwelling System (1967-2006). Colonic manometric patterns were subdivided into high-amplitude propagating contractions, low-amplitude propagating contractions, absence of contractions, and low-amplitude simultaneous contractions. Therefore, it is highly relevant to understand how IAV interacts with and infects mature DCs. Insulin-resistant adipocytes, characterized by low liposynthetic capacity and high lipolytic capacity, cause increased release of free fatty acids (FFA).

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Abstracts from the 62nd scientific sessions: American Heart Association. The interrelationship between serotonin and lipid peroxidation products during experimental wound healing. The natural history of caliceal diverticula in children is unknown. Tools that are better suited for the present dynamic populations are needed and the Internet presents a powerful alternative for the collection of data with several intrinsic features still unexplored. Finally, the strengths/weaknesses of global 3D-QSAR descriptors over local CoMFA-like methods, as well as the main differences between WHIM-based and autocorrelation-based vectors, are discussed.

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To evaluate the efficacy of epithelial-disruption collagen crosslinking (CXL) for progressive keratoconus using a corneal disruptor device and a riboflavin solution designed for a transepithelial technique. The effect of CTGF on Smad7 expression and its role in the regulation of Smad7 induced by TGF-beta1 in renal tubular cells is unknown. This article reviews data from a number of clinical trials, presentations, and abstracts indicating the importance of the DPP-4 inhibitors sitagliptin, vildagliptin, and alogliptin both alone and in combination with insulin sensitizers in the treatment of type 2 diabetes. Protective effect of fish consumption on colorectal cancer risk. To correlate the pathophysiology of intracranial hypotension syndrome with abnormalities in the brain and spine found through magnetic resonance imaging. Nevertheless, several components of this hypothesis, including the role of generalist herbivores, remain relatively unexplored.

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Improving periodontal outcomes: merging clinical and behavioral science. of 3 alpha-diol DP per week for 2 weeks also induced basal cell proliferation. The patients were divided into two groups that were treated with volar plates or orthogonal plates. The macrophages were the direct target of this inhibition as shown by pretreating T cells and macrophages separately with CsA. Psychoeducational intervention has shown to be effective in reducing postconcussive symptoms in studies done with acute civilian samples, but the efficacy of psychoeducational interventions with individuals who served in combat or have chronic complaints remains unclear. Detergent fractionation with subsequent subtractive suppression hybridization as a tool for identifying genes coding for plasma membrane proteins. To evaluate the performance of the SoftPerm contact lens in patients with irregular astigmatism caused by keratoconus.

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Wendler glottoplasty: an effective pitch raising surgery in male-to-female transsexuals. In the second experiment two groups of researchers, from Ancona and Kuopio, measured one field from five different samples of transitional cell tumours (including the case of grade II carcinoma). We searched Ovid MEDLINE, the Cochrane Central Register of Controlled Trials, and Google Scholar databases and also the reference lists of relevant publications for eligible studies. The maps are available to the public on the Internet and through the activities of Iowa Consortium for Comprehensive Cancer Control partners. The results of early active and passive motion, measured at 6 months, were comparable to those from static splinting. This article describes a novel genome-wide statistical approach to the detection of specific DNA sequence motifs based on similarities between the promoters of similarly expressed genes.

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The effect of hyperthermia on liver histology, oxidative stress and disease resistance of the Wuchang bream, Megalobrama amblycephala. High utilization of health care services by fibromyalgia patients. Counseling relating to birth preparedness is an essential component of the WHO Focused Antenatal Care model. Occurrence of estrogenic mycotoxin - Zearalenone in aqueous environmental samples with various NOM content. Alternatively, reagents containing azo functionalities are collisionally activated to yield radical sites on either side of the azo group. At high concentrations, N-LF stimulated cell proliferation in immature Caco-2 cells, as judged by 3H-thymidine incorporation.

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