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Xenical is a medicine used in the treatment of obesity. It helps the body in blocking the absorption of fats from the small intestines and stomach. Xenical should be taken along with food in the dose and duration as per prescription.

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Cobese, Lipophage, Nipocut, Obelit, Obfree, Obilix, Obitrol, Olisat, Orlica, Orlimac, Orlistat, Orlitroy, Reeshape, Slimfast, Troyslim, Vyfat, Zerofat

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Also known as: Orlistat


Xenical capsules are manufactured by Roche. The active component of Xenical is Orlistat (also known as tetrahydrolipstatin) – a gastrointestinal lipase inhibitor. Xenical is recommended to control obesity in patients with the BMI greater or equal to 30 kg/m² (or with BMI greater or equal to 28 kg/m² with associated risk factors). Taking Xenical helps to lose weight, keeps from gaining it back and thus reduces many health risks that come with obesity, including heart disease, diabetes, high blood pressure etc.


Xenical is taken orally 3 times a day during the main meal or up to 1 hour after the meal. The diet of the patient should include three main meals, containing the daily dose of fat, carbohydrate, and protein. The daily intake of fat should be no more than 30% of your total daily caloric intake (e.g., eating 1200 calories per day, no more than 360 of those calories should be in the form of fat). The dose of Xenical should be omitted if a meal is missed or does not contain fat. Treatment with Xenical should not continue for more than 6 months and should be stopped after 12 weeks if patient has been unable to lose at least 5 % of the body weight. If you lose enough weight for your BMI to fall below 28 kg/m², Xenical can no longer be supplied.


If an overdose occurs and you are not feeling well, you should seek emergency medical attention or contact your healthcare provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) and away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Xenical if you are allergic to Orlistat or to other ingredients. Do not take Xenical if you're pregnant, plan to have a baby or breastfeeding. Do not take Xenical usage in case of having anorexia or bulimia, diabetes, chronic malabsorption syndrome, cholestasis (liver disorder), gallbladder disease, kidney disease (kidney stones). Do not take Xenical if you are taking other medications for weight loss, antidiabetes drugs, medications aimed to lower cholesterol like pravastatin (Pravachol), vitamins A/E and K, cyclosporine (Sandimmune, Neoral), beta-carotene, anticoagulants (e.g. warfarin), ciclosporin (immunosuppressant for organ transplantation), iodine salts and/or levothyroxine, amiodarone (for arrhythmia), drugs to treat HIV, antidepressants. Avoid high-fat meals while taking Xenical.

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